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Embryonal Tumor: Molecular Characterization

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Tumors of the Central Nervous System, Volume 13

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 13))

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Abstract

Central Nervous System (CNS) embryonal tumors are malignant neoplasms that share the predilection for the pediatric age, the tendency to early disseminate throughout the CNS via the cerebro spinal fluid, the high mortality and the significant long-term morbidity for survivors.

The pathological diagnose of these tumors on the basis of the morphological analysis may be sometimes difficult, and also not all of these tumors, with an equal stage and treatment, have the same behavior. The application of basic research findings to clinical oncology has led to new approaches to the diagnosis, prognosis, and treatment of these tumors. In this chapter we discuss the molecular biology of the CNS embryonal tumor with particular emphasis on that aspects having clinical impact.

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Author information

Authors and Affiliations

  1. Pathology Unit, Meyer Hospital, Florence, Italy

    Anna Maria Buccoliero

  2. Department of Biomedicine, Careggi Hospital, Florence, Italy

    Francesca Castiglione, Duccio Rossi Degl’Innocenti, Daniela Moncini, Milena Paglierani, Gianna Baroni, Antonella Simoni & Gian Luigi Taddei

  3. Neurosurgery Unit, Meyer Hospital, Florence, Italy

    Lorenzo Genitori

Authors
  1. Anna Maria Buccoliero
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  2. Francesca Castiglione
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  3. Duccio Rossi Degl’Innocenti
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  4. Daniela Moncini
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  5. Milena Paglierani
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  6. Gianna Baroni
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  7. Antonella Simoni
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  8. Lorenzo Genitori
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  9. Gian Luigi Taddei
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Corresponding author

Correspondence to Anna Maria Buccoliero .

Editor information

Editors and Affiliations

  1. Department of Biological Sciences, Kean University, Room 213, Library Building, Union, New Jersey, USA

    M.A. Hayat

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Buccoliero, A.M. et al. (2014). Embryonal Tumor: Molecular Characterization. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 13. Tumors of the Central Nervous System, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7602-9_1

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  • DOI: https://doi.org/10.1007/978-94-007-7602-9_1

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-7601-2

  • Online ISBN: 978-94-007-7602-9

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