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Cytoglobin and Neuroglobin in the Human Brainstem and Carotid Body

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Neurobiology of Respiration

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 788))

Abstract

The aim of the present study was to evaluate the presence of Neuroglobin (Ngb) and Cytoglobin (Cygb) in the solitary tract nucleus (STN) and in the carotid body of human subjects. Transverse serial sections of formalin-fixed, paraffin-embedded brainstems, taken from six subjects, were investigated. Ngb and Cygb are expressed in both the structures. Differences in expression of Ngb and Cygb among dorsal and ventral area of the STN may be related to their different functions and different metabolic demands. Because the STN plays an important role in the processing of cardiovascular and respiratory reflex inputs, Ngb and Cygb may play an integrative central modulatory action for the two systems.

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Correspondence to C. Di Giulio .

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Di Giulio, C. et al. (2013). Cytoglobin and Neuroglobin in the Human Brainstem and Carotid Body. In: Pokorski, M. (eds) Neurobiology of Respiration. Advances in Experimental Medicine and Biology, vol 788. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6627-3_9

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