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Current Topics in Pathology pp 161–220Cite as

The Myothelia (Myoepithelial Cells)

Normal State; Regressive Changes; Hyperplasia; Tumors

  • Conference paper

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 53))

Abstract

The myoepithelial cells are indeed a fascinating type of cell, in that they appear to belong to two widely divergent types of tissues, namely the epithelium and the mesenchyma. This two-sided nature is expressed not only by their position (on the one hand they are connected in typical manner with the secreting epithelium, whereas on the other hand they interact with the stroma and the basal membrane in the same way as smooth muscle fibres), but also by their possession of potentialities of both kinds of tissue, although these potentialities become apparent only under pathological conditions of growth. This concept is the key-note of the following paper, whose purpose is to report a comparative study of the myoepithelia of various organs. Many phenomena that were detectable and detected in only one organ, will be used to elucidate certain otherwise obscure changes in other organs. First we shall examine the normal myoepithelia of various tissues (I), then consider regressive changes (II) and hyperplasia (III), in order to apply the information thus obtained to the problem of tumors (IV, V). To some extent, therefore, this paper constitutes a continuation of my paper from 1939 “On the myothelia of the mammary gland”. Additional material has been collected since then; unfortunately, however, some of the relevant documents were lost during the war and in the post-war period.

With the generous support of the Nordrhein-Westfalen Office for Research. I dedicate this paper in gratitude to my technical assistants, Countess M. Matuschka and M. Haland, and also to all fellow-workers in Vienna, Berlin, Prague, Salzburg, Marburg, Bonn and Bogotá who prepared the necessary sections.

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  1. Patholog. Institute, Bonn University, 5300, (Germ. Fed. Rep.) Postfach, Bonn 1, Germany

    H. Hamperl

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  1. Würzburg, Germany

    H.-W. Altmann

  2. Hanover, Germany

    K. Benirschke  & P. Cohrs  & 

  3. Tübingen, Germany

    A. Bohle

  4. Chapel Hill, USA

    K. M. Brinkhous

  5. Bern, Switzerland

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  6. München, Germany

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  7. Bonn, Germany

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  8. Münster, Germany

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  9. Zürich, Switzerland

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  10. Hiroshima, Japan

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  11. Chicago, USA

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  13. Kiel, Germany

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  14. Düsseldorf, Germany

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  15. Freiburg, Germany

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  16. Hamburg, Germany

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  18. Basel, Switzerland

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Hamperl, H. (1970). The Myothelia (Myoepithelial Cells). In: Altmann, HW., et al. Current Topics in Pathology. Current Topics in Pathology, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-30514-0_3

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