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Reactionary and Reparative Dentin-Like Structures

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The Dental Pulp

Abstract

Reactionary dentin-like is produced by odontoblasts and Hoehl’s cell after a carious decay, beneath a calciotraumatic line. Five SIBLINGs have been identified, together with the metalloproteinase-2 (MMP-2), whereas SMAD-2 and SMAD-4 are implicated in the synthesis of collagen. Reparative dentin is similar to a bone-like (osteodentin) structure and produced by pulp cells. BMPs, OP-1 or BMP-7, and other growth factors have also been identified in the reparative dentin. A series of SIBLINGs, fibronectin, ameloblastin, MMP-3, and MMP-9 are implicated in the formation of reparative dentin allowing the closure of a pulp exposure.

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Authors and Affiliations

  1. Department of Oral Biology, Institut National de la Santé et de la Recherche Médicale, Université Paris Descartes, 45 Rue des Saints Pères, Paris, 75006, France

    Michel Goldberg DDS, PhD

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  1. Michel Goldberg DDS, PhD
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Correspondence to Michel Goldberg DDS, PhD .

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  1. Department of Oral Biology, Institut National de la Santé et de la, Recherche Médicale, Université Paris Descartes, Paris, Paris, France

    Michel Goldberg

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Goldberg, M. (2014). Reactionary and Reparative Dentin-Like Structures. In: Goldberg, M. (eds) The Dental Pulp. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55160-4_10

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  • DOI: https://doi.org/10.1007/978-3-642-55160-4_10

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-55159-8

  • Online ISBN: 978-3-642-55160-4

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