Abstract
Nitric oxide (NO) is a diatomic free radical consisting of one nitrogen and one oxygen atom (Fig. 12.1).
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- 1.
William Harvey (1578–1657), established the heart as the center of the blood system in the seventeenth century.
- 2.
Ascanio Sobrero (1812–1888), an Italian chemist, first synthesized nitric oxide.
- 3.
Alfred Nobel (1833–1896), Swedish chemist, inventor, and engineer. Among others, he was also the inventor of dynamite.
- 4.
William Murrell (1853–1912), physician who used nitroglycerin as a remedy for angina pectoris.
- 5.
Robert Francis Furchgott (1916–2009) discovered the role of the endothelial cell.
- 6.
Louis José Ignarro found that “endothelium-derived relaxing factor” (EDRF) was released by endothelial cells.
- 7.
Ferid Murad discovered that endothelium-derived relaxing factor (EDRF) was nitric oxide (NO).
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Flammer, J., Mozaffarieh, M., Bebie, H. (2013). Nitric Oxide. In: Basic Sciences in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32261-7_12
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DOI: https://doi.org/10.1007/978-3-642-32261-7_12
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