Abstract
Deep vein thrombosis (DVT) can be seen in almost all races and age groups. Although many of the risk factors have been identified and several agents are currently used in its management and prevention, still it is not possible to predict accurately its development, symptoms, and progression to pulmonary embolism (PE) in a particular setting. Every year, at least 100,000 individuals die of DVT and PE in the USA. DVT is a complication usually occurring after hip fractures of the elderly or surgery for total joint replacement or spinal stenosis and mostly affecting elderly and bedridden patients. But, the frequency of DVT is quite high among athletes and professional sport players. In general, DVT risk is 85% greater among athletes when compared to normal population due to the specific risk factors of sports. DVT and PE may be seen in athletes actively taking part in sportive activities, traveling, exposing to sportive trauma, or undergoing surgery for any reason, even at a relatively young age. In this chapter, the risk factors, diagnosis, prevention, and treatment of DVT and PE in athletes are discussed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ali, M.S., Kutty, M.S., Corea, J.R.: Deep vein thrombosis in a jogger. Am. J. Sports Med. 12, 169 (1984)
Altintas, F.: Thromboembolism in hip and knee arthroplasties. Acta Orthop. Traumatol. Turc. 34, 100–109 (2000)
Altintas, F., Gurbuz, H., Erdemli, B., Atilla, B., Ustaoglu, R.G., Ozic, U., et al.: Venous thromboembolism prophylaxis in major orthopaedic surgery: a multicenter, prospective, observational study. Acta Orthop. Traumatol. Turc. 42, 322–327 (2008)
Arfvidsson, B., Eklof, B., Kistner, R.L., Ogawa, T., Parsi, K.: A prospective evaluation of the risk for venous leg thrombosis associated with prolonged air travel: a pilot study. Cardiovasc. Surg. 9, 455–457 (2001)
Arko, F.R., Harris, E.J., Zarins, C.K., Olcott, C.: Vascular complications in high-performance athletes. J. Vasc. Surg. 33, 935–942 (2001)
Barritt, D.W., Jordan, S.C.: Anticoagulant drugs in the treatment of pulmonary embolism. a controlled trial. Lancet 1, 1309–1312 (1960)
Beksac, B., Gonzalez Della Valle, A., Salvati, E.A.: Thromboembolic disease after total hip arthroplasty: who is at risk? Clin. Orthop. Relat. Res. 453, 211–224 (2006)
Buller, H.R., Agnelli, G., Hull, R.D., Hyers, T.M., Prins, M.H., Raskob, G.E.: Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126, 401S–428S (2004)
Buller, H.R., Sohne, M., Middeldorp, S.: Treatment of venous thromboembolism. J. Thromb. Haemost. 3, 1554–1560 (2005)
Bushnell, B.D., Horton, J.K., McDonald, M.F., Robertson, P.G.: Perioperative medical comorbidities in the orthopaedic patient. J. Am. Acad. Orthop. Surg. 16, 216–227 (2008)
Cashman, J.D., McCredie, J., Henry, D.A.: Intravenous contrast media: use and associated mortality. Med. J. Aust. 155, 618–623 (1991)
Collins, J.: Thromboembolic disease related to air travel: what you need to know. Semin. Roentgenol. 40, 1–2 (2005)
de Valois, J.C., van Schaik, C.C., Verzijlbergen, F., van Ramshorst, B., Eikelboom, B.C., Meuwissen, O.J.: Contrast venography: from gold standard to ‘golden backup’ in clinically suspected deep vein thrombosis. Eur. J. Radiol. 11, 131–137 (1990)
Dulicek, P., Maly, J., Pecka, M., Beranek, M., Cermakova, E., Maly, R.: Venous thromboembolism in young female while on oral contraceptives: high frequency of inherited thrombophilia and analysis of thrombotic events in 400 Czech women. Clin. Appl. Thromb. Hemost. 15, 567–573 (2009)
Echlin, P.S., Upshur, R.E., McKeag, D.B., Jayatilake, H.P.: Traumatic deep vein thrombosis in a soccer player: a case study. Thromb. J. 2, 8 (2004)
Fink, M.L., Stoneman, P.D.: Deep vein thrombosis in an athletic military cadet. J. Orthop. Sports Phys. Ther. 36, 686–697 (2006)
Fraser, D.G., Moody, A.R., Morgan, P.S., Martel, A.L., Davidson, I.: Diagnosis of lower-limb deep venous thrombosis: a prospective blinded study of magnetic resonance direct thrombus imaging. Ann. Intern. Med. 136, 89–98 (2002)
Fremont, B., Pacouret, G., De Labriolle, A., Magdelaine, B., Puglisi, R., Charbonnier, B.: Exercise deep venous thrombosis: myth or reality? About three cases of pulmonary embolism in long-distance runners. Arch. Mal. Coeur Vaiss. 100, 519–523 (2007)
Geerts, W.H., Pineo, G.F., Heit, J.A., Bergqvist, D., Lassen, M.R., Colwell, C.W., et al.: Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126, 338S–400S (2004)
Goodacre, S., Sampson, F., Thomas, S., van Beek, E., Sutton, A.: Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis. BMC Med. Imaging 5, 6 (2005)
Hariri, A., Nourissat, G., Dumontier, C., Doursounian, L.: Pulmonary embolism following thrombosis of the brachial vein after shoulder arthroscopy. a case report. Rev. Chir. Orthop. Reparatrice Appar. Mot. 95, 377–379 (2009)
Hilberg, T., Jeschke, D., Gabriel, H.H.: Hereditary thrombophilia in elite athletes. Med. Sci. Sports Exerc. 34, 218–221 (2002)
Hirsh, J., Guyatt, G., Albers, G.W., Harrington, R., Schunemann, H.J.: Executive summary: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133, 71S–109S (2008)
Hirsh, J., Hoak, J.: Management of deep vein thrombosis and pulmonary embolism. A statement for healthcare professionals. Council on Thrombosis (in consultation with the Council on Cardiovascular Radiology), American Heart Association. Circulation 93, 2212–2245 (1996)
Holzheimer, R.G., Stautner-Bruckmann, C.: Calf pain in runners may be caused by venous insufficiency. Eur. J. Med. Res. 13, 218–220 (2008)
Howell, M.D., Geraci, J.M., Knowlton, A.A.: Congestive heart failure and outpatient risk of venous thromboembolism: a retrospective, case-control study. J. Clin. Epidemiol. 54, 810–816 (2001)
Hughes, D.G., Dixon, P.M.: Pool players’ thrombosis. Br. Med. J. (Clin. Res. Ed.) 295, 1652 (1987)
Hull, R., Hirsh, J., Sackett, D.L., Taylor, D.W., Carter, C., Turpie, A.G., et al.: Clinical validity of a negative venogram in patients with clinically suspected venous thrombosis. Circulation 64, 622–625 (1981)
Hurley, W.L., Comins, S.A., Green, R.M., Canizzaro, J.: Atraumatic subclavian vein thrombosis in a collegiate baseball player: a case report. J. Athl. Train. 41, 198–200 (2006)
Ilahi, O.A., Reddy, J., Ahmad, I.: Deep venous thrombosis after knee arthroscopy: a meta-analysis. Arthroscopy 21, 727–730 (2005)
Kahn, S.R., Ginsberg, J.S.: The post-thrombotic syndrome: current knowledge, controversies, and directions for future research. Blood Rev. 16, 155–165 (2002)
Kearon, C.: Natural history of venous thromboembolism. Circulation 107, I22–I30 (2003)
Kiens, B., Essen-Gustavsson, B., Christensen, N.J., Saltin, B.: Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training. J. Physiol. 469, 459–478 (1993)
Lapostolle, F., Surget, V., Borron, S.W., Desmaizieres, M., Sordelet, D., Lapandry, C., et al.: Severe pulmonary embolism associated with air travel. N. Engl. J. Med. 345, 779–783 (2001)
Liljeqvist, S., Hellden, A., Bergman, U., Soderberg, M.: Pulmonary embolism associated with the use of anabolic steroids. Eur. J. Intern. Med. 19, 214–215 (2008)
McCaffrey, R., Bishop, M., Adonis-Rizzo, M., Williamson, E., McPherson, M., Cruikshank, A., et al.: Development and testing of a DVT risk assessment tool: providing evidence of validity and reliability. Worldviews Evid. Based Nurs. 4, 14–20 (2007)
Merlen, J.F., Coget, J.M., Sarteel, A.M.: True or false varicose veins in sportsmen? (Result of a survey). Phlebologie 33, 501–506 (1980)
Meyering, C., Howard, T.: Hypercoagulability in athletes. Curr. Sports Med. Rep. 3, 77–83 (2004)
Molz, A.B., Heyduck, B., Lill, H., Spanuth, E., Rocker, L.: The effect of different exercise intensities on the fibrinolytic system. Eur. J. Appl. Physiol. Occup. Physiol. 67, 298–304 (1993)
Nordstrom, M., Lindblad, B., Bergqvist, D., Kjellstrom, T.: A prospective study of the incidence of deep-vein thrombosis within a defined urban population. J. Intern. Med. 232, 155–160 (1992)
Oger, E., Mottier, D.: Current status of anticoagulants. Presse Méd. 29, 1079–1082 (2000)
Pell, RFt, Khanuja, H.S., Cooley, G.R.: Leg pain in the running athlete. J. Am. Acad. Orthop. Surg. 12, 396–404 (2004)
Polzhofer, G.K., Petersen, W., Hassenpflug, J.: Thromboembolic complication after arthroscopic shoulder surgery. Arthroscopy 19, E129–E132 (2003)
Rathbun, S.: Cardiology patient pages. The surgeon general’s call to action to prevent deep vein thrombosis and pulmonary embolism. Circulation 119, e480–e482 (2009)
Reinharez, D.: Varices in athletes. Phlebologie 22, 263–269 (1969)
Reinharez, D.: Fitness and competitive sports in venous pathology. Phlebologie 33, 513–521 (1980)
Reinharez, D., Monsonego, J.: Veins and contraception. Contracept Fertil. Sex (Paris) 13, 131–136 (1985)
Rhodes, J.M., Cho, J.S., Gloviczki, P., Mozes, G., Rolle, R., Miller, V.M.: Thrombolysis for experimental deep venous thrombosis maintains valvular competence and vasoreactivity. J. Vasc. Surg. 31, 1193–1205 (2000)
Ribeiro, J., Almeida-Dias, A., Ascensao, A., Magalhaes, J., Oliveira, A.R., Carlson, J., et al.: Hemostatic response to acute physical exercise in healthy adolescents. J. Sci. Med. Sport 10, 164–169 (2007)
Roberts, W.O., Christie Jr., D.M.: Return to training and competition after deep venous calf thrombosis. Med. Sci. Sports Exerc. 24, 2–5 (1992)
Samama, M.M., Dahl, O.E., Quinlan, D.J., Mismetti, P., Rosencher, N.: Quantification of risk factors for venous thromboembolism: a preliminary study for the development of a risk assessment tool. Haematologica 88, 1410–1421 (2003)
Scarvelis, D., Wells, P.S.: Diagnosis and treatment of deep-vein thrombosis. CMAJ 175, 1087–1092 (2006)
Schrecengost, J.E., LeGallo, R.D., Boyd, J.C., Moons, K.G., Gonias, S.L., Rose Jr., C.E., et al.: Comparison of diagnostic accuracies in outpatients and hospitalized patients of D-dimer testing for the evaluation of suspected pulmonary embolism. Clin. Chem. 49, 1483–1490 (2003)
Shebel, N.D., Marin, A.: Effort thrombosis (Paget-Schroetter syndrome) in active young adults: current concepts in diagnosis and treatment. J. Vasc. Nurs. 24, 116–126 (2006)
Siekierzynska-Czarnecka, A., Polowiec, Z., Kulawinska, M., Rowinska-Zakrzewska, E.: Death caused by pulmonary embolism in a body builder taking anabolic steroids (metanabol). Wiad. Lek. 43, 972–975 (1990)
Slawski, D.P.: Deep venous thrombosis complicating rupture of the medial head of the gastrocnemius muscle. J. Orthop. Trauma 8, 263–264 (1994)
Stein, P.D., Fowler, S.E., Goodman, L.R., Gottschalk, A., Hales, C.A., Hull, R.D., et al.: Multidetector computed tomography for acute pulmonary embolism. N. Engl. J. Med. 354, 2317–2327 (2006)
Tick, L.W., Kramer, M.H., Rosendaal, F.R., Faber, W.R., Doggen, C.J.: Risk factors for post-thrombotic syndrome in patients with a first deep venous thrombosis. J. Thromb. Haemost. 6, 2075–2081 (2008)
Tsai, A.W., Cushman, M., Rosamond, W.D., Heckbert, S.R., Polak, J.F., Folsom, A.R.: Cardiovascular risk factors and venous thromboembolism incidence: the longitudinal investigation of thromboembolism etiology. Arch. Intern. Med. 162, 1182–1189 (2002)
Wells, P.S., Anderson, D.R., Rodger, M., Forgie, M., Kearon, C., Dreyer, J., et al.: Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N. Engl. J. Med. 349, 1227–1235 (2003)
Westerbeek, R.E., Van Rooden, C.J., Tan, M., Van Gils, A.P., Kok, S., De Bats, M.J., et al.: Magnetic resonance direct thrombus imaging of the evolution of acute deep vein thrombosis of the leg. J. Thromb. Haemost. 6, 1087–1092 (2008)
Zimlich, R.H., Fulbright, B.M., Friedman, R.J.: Current status of anticoagulation therapy after total hip and total knee arthroplasty. J. Am. Acad. Orthop. Surg. 4, 54–62 (1996)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Altintaş, F., Uluçay, Ç. (2012). Deep Vein Thrombosis in Athletes: Prevention and Treatment. In: Doral, M. (eds) Sports Injuries. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15630-4_141
Download citation
DOI: https://doi.org/10.1007/978-3-642-15630-4_141
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-15629-8
Online ISBN: 978-3-642-15630-4
eBook Packages: MedicineMedicine (R0)