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Coevolutionary Method for Gene Selection and Parameter Optimization in Microarray Data Analysis

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Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 5864))

Abstract

This paper presents a coevolutionary algorithm based personalized modeling (cEAP) for gene selection and parameter optimization for microarray data analysis. The classification of different tumor types is a main application in microarray data analysis and of great importance in cancer diagnosis and drug discovery. However, the construction of an effective classifier involves gene selection and parameter optimization, which poses a big challenge to bioinformatics research. We have explored cEAP algorithm on four benchmark microarray datasets for gene selection and parameter optimization. The experimental results have shown that cEAP is an efficient method for co-evolving complex optimization problems in microarray data analysis.

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Hu, Y., Kasabov, N. (2009). Coevolutionary Method for Gene Selection and Parameter Optimization in Microarray Data Analysis. In: Leung, C.S., Lee, M., Chan, J.H. (eds) Neural Information Processing. ICONIP 2009. Lecture Notes in Computer Science, vol 5864. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-10684-2_54

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  • DOI: https://doi.org/10.1007/978-3-642-10684-2_54

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-10682-8

  • Online ISBN: 978-3-642-10684-2

  • eBook Packages: Computer ScienceComputer Science (R0)

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