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Noncoding RNAs in the Development, Function and Pathologies of the Central Nervous System

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Therapeutic Ribonucleic Acids in Brain Tumors

Abstract

Noncoding RNAs (ncRNAs) are now recognized as important components of regulatory networks governing gene expression in all organisms. In mammals ncRNAs have been shown to regulate many key processes associated with the development and maintenance of specific gene expression profiles. In the nervous system many various classes of ncRNAs play a role in neural cells differentiation and activity. Aberrant expression of noncoding transcripts in the cells of the nervous system is often associated with severe disorders involving neurodegenerative diseases, psychiatric conditions and cancer.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Noskowskiego 12, 61-704, Poznan, Poland

    Maciej Szymański & Jan Barciszewski

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  1. Maciej Szymański
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  2. Jan Barciszewski
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Correspondence to Maciej Szymański .

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Editors and Affiliations

  1. Inst. Chemie und Biochemie, FU Berlin, Thielallee 63, Berlin, 14195, Germany

    Volker A. Erdmann

  2. Inst. Neuropathologie, Universitätsklinikum Düsseldorf, Moorenstr. 5, Düsseldorf, 40225, Germany

    Guido Reifenberger

  3. Inst. Bioorganic Chemistry, PAN Poznan, ul. Z. Noskowskiego 12/14, Poznan, 61-704, Poland

    Jan Barciszewski

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Szymański, M., Barciszewski, J. (2009). Noncoding RNAs in the Development, Function and Pathologies of the Central Nervous System. In: Erdmann, V., Reifenberger, G., Barciszewski, J. (eds) Therapeutic Ribonucleic Acids in Brain Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00475-9_20

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