Skip to main content

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume S7))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hofmeister, A.E.M.; Grabowski, R.; Linder, D.; Buckel, W.: L-Serine and lthreonine dehydratase from Clostridium propionicum. Two enzymes with different prosthetic groups. Eur. J. Biochem., 215, 341–349 (1993)

    Article  CAS  PubMed  Google Scholar 

  2. Laakmann-Ditges, G.; Klemme, J.H.: Amino acid metabolism in the thermophilic phototroph, Chloroflexus aurantiacus: properties and metabolic role of two L-threonine (L-serine) dehydratases. Arch. Microbiol., 149, 249–254 (1988)

    Article  CAS  Google Scholar 

  3. Laakmann-Ditges, G.; Klemme, J.H.: Occurence of two L-threonine (L-serine) dehydratases in thermophile Chloroflexus aurantiacus. Arch. Microbiol., 144, 219–221 (1986)

    Article  CAS  Google Scholar 

  4. Bode, R.; Birnbaum, D.: Threonine dehydratase activity from several yeast species is activated and affected by phosphate. FEMS Microbiol. Lett., 37, 189–192 (1986)

    Article  CAS  Google Scholar 

  5. Bode, R.; Schult, I.; Birnbaum, D.: Purification and some properties of L-threonine dehydratase from Candida maltosa. J. Basic Microbiol., 26, 443–451 (1986)

    Article  CAS  Google Scholar 

  6. Oda, Y.; Nakano, Y.; Kitaoka, S.: Occurence and some properties of two threonine dehydratases in Euglena gracilis. J. Gen. Microbiol., 129, 57–61 (1983)

    CAS  Google Scholar 

  7. Kim, S.S.; Datta, P.: Chemical characterization of biodegradative threonine dehydratases from two enteric bacteria. Biochim. Biophys. Acta, 706, 27–35 (1982)

    CAS  PubMed  Google Scholar 

  8. Yoshida, H.; Hanada, K.; Ohsawa, H.; Kumagai, H.; Yamada, H.: Biosynthetic threonine deaminase from Proteus morganii. Agric. Biol. Chem., 46, 1035–1042 (1982)

    CAS  Google Scholar 

  9. Mak, W.W.N.; Pitot, H.C.: Increase of L-serine dehydratase activity under gluconeogenic conditions in adult-rat hepatocytes cultured on collagen gel/nylon mesh. Biochem. J., 198, 499–504 (1981)

    CAS  PubMed  Google Scholar 

  10. Crout, D.H.G.; Gregorio, M.V.M.; Miller, U.S.; Komatsubara, S.; Kisumi, M.; Chibata, I.: Stereochemistry of the conversions of L-threonine and D-threonine into 2-oxobutanoate by the L-threonine and D-threonine dehydratases of Serratia marcescens. Eur. J. Biochem., 106, 97–105 (1980)

    Article  CAS  PubMed  Google Scholar 

  11. Proteau, G.; Silver, M.: Effects of amino acids on Thiobacillus acidophilus. II. Threonine deaminase. Can. J. Microbiol., 26, 385–388 (1980)

    CAS  PubMed  Google Scholar 

  12. Lam, V.M.S.; Yeung, Y.G.: Properties of threonine deaminase from Pseudomonas aeruginosa. FEMS Microbiol. Lett., 3, 219–221 (1978)

    Article  CAS  Google Scholar 

  13. Sharma, R.K.; Mazumder, R.: Purification, properties, and feedback control of L-threonine dehydratase from spinach. J. Biol. Chem., 245, 3008–3014 (1970)

    CAS  PubMed  Google Scholar 

  14. Kumagai, H.; Nishimura, T.; Yamada, H.: Biodegradative threonine deaminase from Proteus morganii. Agric. Biol. Chem., 42, 613–621 (1978)

    CAS  Google Scholar 

  15. Bell, S.C.; Turner, J.M.: Bacterial catabolism of threonine. Threonine degradation initiated by L-threonine hydro-lyase (deaminating) in a species of Corynebacterium. Biochem. J., 164, 579–587 (1977)

    CAS  PubMed  Google Scholar 

  16. Saeki, Y.; Ito, S.; Shizuta, Y.; Hayaishi, O.; Kagamiyama, H.; Wada, H.: Subunit structure of biodegradative threonine deaminase. J. Biol. Chem., 252, 2206–2208 (1977)

    CAS  PubMed  Google Scholar 

  17. Shizuta, Y.; Hayaishi, O.: Regulation of biodegradative threonine deaminase. Curr. Top. Cell. Regul., 11, 99–146 (1976)

    CAS  PubMed  Google Scholar 

  18. Muramatsu, N.; Nosoh, Y.: Some catalytic and molecular properties of threonine deaminase from Bacillus stearothermophilus. J. Biochem., 80, 485–490 (1996)

    Google Scholar 

  19. Koerner, K.; Rahimi-Laridjani, I.; Grimminger, H.: Purification of biosynthetic threonine deaminase from Escherichia coli. Biochim. Biophys. Acta, 397, 220–230 (1975)

    CAS  PubMed  Google Scholar 

  20. Kagan, Z.S.; Dorozhko, A.I.; Kovaleva, S.V.; Yakovleva, L.I.: Studies of homogeneous biosynthetic L-threonine dehydratase from Escherichia coli K-12. Some kinetic properties and molecular multiplicity. Biochim. Biophys. Acta, 403, 208–220 (1975)

    CAS  PubMed  Google Scholar 

  21. Luginbuhl, G.H.; Hofler, J.G.; Decedue, C.J.; Burns, R.O.: Biodegradative lthreonine deaminase of Salmonella typhimurium. J. Bacteriol., 120, 559–561 (1974)

    CAS  PubMed  Google Scholar 

  22. Doonan, S.; Koerner, D.H.; Schmutzler, W.; Vernon, C.A.: Inducibility and some properties of the threonine dehydratase of sheep liver. Biochem. J., 144, 533–541 (1974)

    CAS  PubMed  Google Scholar 

  23. Cohn, M.S.; Phillips, A.T.: Purification and characterization of a B6-independent threonine dehydratase from Pseudomonas putida. Biochemistry, 13, 1208–1214 (1974)

    Article  CAS  PubMed  Google Scholar 

  24. Calhoun, D.H.; Rimerman, R.A.; Hatfield, G.W.: Threonine deaminase from Escherichia coli. I. Purification and properties. J. Biol. Chem., 248, 3511–3516 (1973)

    CAS  PubMed  Google Scholar 

  25. Calhoun, D.H.; Kuska, J.S.; Hatfield, G.W.: Threonine deaminase from Escherichia coli. II. Maturation and physical properties of the enzyme from a mutant altered in its regulation of gene expression. J. Biol. Chem., 250, 127–131 (1974)

    Google Scholar 

  26. Grimminger, H.; Rahimi-Laridjani, I.; Koerner, K.; Lingens, F.: Purification of threonine deaminase from Escherichia coli. FEBS Lett., 35, 273–275 (1973)

    Article  CAS  PubMed  Google Scholar 

  27. Higa, E.H.; Ramaley, R.F.: Purification and properties of threonine deaminase from the X-1 isolate of the genus Thermus. J. Bacteriol., 114, 556–562 (1973)

    CAS  PubMed  Google Scholar 

  28. Barritt, G.J.; Morrison, J.F.: Purification and properties of threonine dehydratase from Rhodopseudomonas spheroides. Biochim. Biophys. Acta, 284, 508–520 (1972)

    CAS  PubMed  Google Scholar 

  29. Nath, M.; Sanwal, G.G.: Threonine dehydratase from goat liver. Arch. Biochem. Biophys., 151, 420–426 (1972)

    Article  CAS  PubMed  Google Scholar 

  30. Desai, I.D.; Laub, D.; Anita, N.J.: Comparative characterization of L-threonine dehydratase in seven species of unicellular marine algae. Phytochemistry, 11, 277–287 (1972)

    Article  CAS  Google Scholar 

  31. Park, L.S.; Datta, P.: Inhibition of Escherichia coli biodegradative threonine dehydratase by pyruvate. J. Bacteriol., 138, 1026–1028 (1979)

    CAS  PubMed  Google Scholar 

  32. Leoncini, R.; Vannoni, D.; di Pietro, C.; Guerranti, R.; Rosi, F.; Pagani, R.; Marinello, E.: Restoration of rat liver L-threonine dehydratase activity by pyridoxamine 5-phosphate: the half-transaminating activity of L-threonine dehydratase and its regulatory role. Biochim. Biophys. Acta, 1425, 411–418 (1998)

    CAS  PubMed  Google Scholar 

  33. Pagani, R.; Leoncini, R.; Terzuoli, L.; Guerranti, R.; Marinello, E.: In vitro regulation of rat liver L-threonine deaminase by different effectors. Enzyme, 43, 122–128 (1990)

    CAS  PubMed  Google Scholar 

  34. Burns, R.O.; Hofler, J.G.; Luginbuhl, G.H.: Threonine deaminase from Salmonella typhimurium. Substrate-specific patterns of inhibition in an activator site-deficient form of the enzyme. J. Biol. Chem., 254, 1074–1079 (1979)

    CAS  PubMed  Google Scholar 

  35. Pagani, R.; Leoncini, R.; Pizzichini, M.; Vannoni, D.; Tabucchi, A.; Marinello: Properties of rat liver L-threonine deaminase. Enzyme Protein, 48, 90–97 (1994)

    CAS  PubMed  Google Scholar 

  36. Sahm, H.; Eggeling, L.; Eikmanns, B.; Kraemer, R.: Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum. Ann. N.Y. Acad. Sci., 782, 25–39 (1996)

    Article  CAS  PubMed  Google Scholar 

  37. Szamosi, I.; Shaner, D.L.; Singh, B.K.: Identification and characterization of a biodegradative form of threonine dehydratase in senescing tomato (Lycopersicon esculentum) leaf. Plant Physiol., 101, 999–1004 (1993)

    CAS  PubMed  Google Scholar 

  38. Eisenstein, E.: Cloning, expression, purification, and characterization of biosynthetic threonine deaminase from Escherichia coli. J. Biol. Chem., 266, 5801–5807 (1991)

    CAS  PubMed  Google Scholar 

  39. Guillouet, S.; Rodal, A.A.; An, G.H.; Lessard, P.A.; Sinskey, A.J.: Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl. Environ. Microbiol., 65, 3100–3107 (1999)

    CAS  PubMed  Google Scholar 

  40. Hashiguchi, K.; Kojima, H.; Sato, K.; Sano, K.: Effects of an Escherichia coli ilvA mutant gene encoding feedback-resistant threonine deaminase on L-isoleucine production by Brevibacterium flavum. Biosci. Biotechnol. Biochem., 61, 105–108 (1997)

    Article  CAS  PubMed  Google Scholar 

  41. Leoncini, R.; Guerranti, R.; Pagani, R.; Marinello, E.: An improved method for purification of L-threonine deaminase from rat liver. J. Biochem. Biophys. Methods, 20, 97–105 (1990)

    Article  CAS  PubMed  Google Scholar 

  42. Choi, B.B.; Kim, S.S.: Inhibition of the biodegradative threonine dehydratase from Serratia marcescens by α-keto acids and their derivatives. J. Biochem. Mol. Biol., 28, 118–123 (1995)

    CAS  Google Scholar 

  43. Leoncini, R.; Pagani, R.; Marinello, E.; Keleti, T.: Double inhibition of lthreonine dehydratase by aminothiols. Biochim. Biophys. Acta, 994, 52–58 (1989)

    CAS  PubMed  Google Scholar 

  44. Gallagher, D.T.; Gilliland, G.L.; Xiao, G.; Zondlo, J.; Fisher, K.E.; Chinchilla, D.; Eisenstein; E.: Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase. Structure, 6, 465–475 (1998)

    Article  CAS  PubMed  Google Scholar 

  45. Eisenstein, E.: Allosteric regulation of biosynthetic threonine deaminase from Escherichia coli: effects of isoleucine and valine on active-site ligand binding and catalysis. Arch. Biochem. Biophys., 316, 311–318 (1995)

    Article  CAS  PubMed  Google Scholar 

  46. Dougall, D.K.: Threonine deaminase from Paul’s Scarlet rose tissue cultures. Phytochemistry, 9, 959–964 (1979)

    Article  Google Scholar 

  47. Moeckel, B.; Eggeling, L.; Sahm, H.: Functional and structural analyses of threonine dehydratase from Corynebacterium glutamicum. J. Bacteriol., 174, 8065–8072 (1992)

    CAS  Google Scholar 

  48. Morbach, S.; Kelle, R.; Winkels, S.; Sahm, H.; Eggeling, L.: Engineering the homoserine dehydrogenase and threonine dehydratase control points to analyse flux towards L-isoleucine in Corynebacterium glutamicum. Appl. Microbiol. Biotechnol., 45, 612–620 (1996)

    Article  CAS  Google Scholar 

  49. Guillouet, S.; Rodal, A.A.; An, G.H.; Gorret, N.; Lessard, P.A.; Sinskey, A.J.: Metabolic redirection of carbon flow toward isoleucine by expressing a catabolic threonine dehydratase in a threonine-overproducing Corynebacterium glutamicum. Appl. Microbiol. Biotechnol., 57, 667–673 (2001)

    Article  CAS  PubMed  Google Scholar 

  50. Wessel, P.M.; Graciet, E.; Douce, R.; Dumas, R.: Evidence for two distinct effector-binding sites in threonine deaminase by site-directed mutagenesis, kinetic, and binding experiments. Biochemistry, 39, 15136–15143 (2000)

    Article  CAS  PubMed  Google Scholar 

  51. Halgand, F.; Wessel, P.M.; Laprevote, O.; Dumas, R.: Biochemical and mass spectrometric evidence for quaternary structure modifications of plant threonine deaminase induced by isoleucine. Biochemistry, 41, 13767–13773 (2002)

    Article  CAS  PubMed  Google Scholar 

  52. Scarselli, M.; Padula, M.G.; Bernini, A.; Spiga, O.; Ciutti, A.; Leoncini, R.; Vannoni, D.; Marinello, E.; Niccolai, N.: Structure and function correlations between the rat liver threonine deaminase and aminotransferases. Biochim. Biophys. Acta, 1645, 40–48 (2003)

    CAS  PubMed  Google Scholar 

  53. Ebmeier, A.; Allison, L.; Cerutti, H.; Clemente, T.: Evaluation of the Escherichia coli threonine deaminase gene as a selectable marker for plant transformation. Planta, 218, 751–758 (2004)

    Article  CAS  PubMed  Google Scholar 

  54. Akagi, S.; Sato, K.; Ohmori, S.: Threonine metabolism in Japanese quail liver. Amino Acids, 26, 235–242 (2004)

    CAS  PubMed  Google Scholar 

  55. Schmitz, G.; Downs, D.M.: Reduced transaminase B (IlvE) activity caused by the lack of yjgF is dependent on the status of threonine deaminase (IlvA) in Salmonella enterica serovar typhimurium. J. Bacteriol., 186, 803–810 (2004)

    Article  CAS  PubMed  Google Scholar 

  56. Garcia, E.L.; Mourad, G.S.: A site-directed mutagenesis interrogation of the carboxy-terminal end of Arabidopsis thaliana threonine dehydratase/deaminase reveals a synergistic interaction between two effector-binding sites and contributes to the development of a novel selectable marker. Plant Mol. Biol., 55, 121–134 (2004)

    Article  CAS  PubMed  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2010). Threonine ammonia-lyase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 4–6 Lyases, Isomerases, Ligases. Springer Handbook of Enzymes, vol S7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85707-5_75

Download citation

Publish with us

Policies and ethics