This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Sallese, M.; Mariggio, S.; Collodel, G.; Moretti, E.; Piomboni, P.; Baccetti, B.; De Blasi, A.: G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells. J. Biol. Chem., 272, 10188–10195 (1997)
Sallese, M.; Lombardi, M.S.; De Blasi, A.: Two isoforms of G protein-coupled receptor kinase 4 identified by molecular cloning. Biochem. Biophys. Res. Commun., 199, 848–854 (1994)
Ambrose, C.; James, M.; Barnes, G.; Lin, C.; Bates, G.; Altherr, M.; Duyao, M.; Groot, N.; Church, D.; Wasmuth, J.J.; et al.: A novel G protein-coupled receptor kinase gene cloned from 4p16.3. Hum. Mol. Genet., 1, 697–703 (1992)
Kunapuli, P.; Benovic, J.L.: Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family. Proc. Natl. Acad. Sci. USA, 90, 5588–5592 (1993)
Premont, R.T.; Koch, W.J.; Inglese, J.; Lefkowitz, R.J.: Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases. J. Biol. Chem., 269, 6832–6841 (1994)
Stoffel, R.H.; Randall, R.R.; Premont, R.T.; Lefkowitz, R.J.; Inglese, J.: Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family. J. Biol. Chem., 269, 27791–27794 (1994)
Benovic, J.L.; Gomez, J.: Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family. J. Biol. Chem., 268, 19521–19527 (1993)
Fehr, C.; Fickova, M.; Hiemke, C.; Reuss, S.; Dahmen, N.: Molecular cloning of rat G-protein-coupled receptor kinase 6 (GRK6) from brain tissue, and its mRNA expression in different brain regions and peripheral tissues. Brain Res. Mol. Brain Res., 49, 278–282 (1997)
Nagayama, Y.; Tanaka, K.; Hara, T.; Namba, H.; Yamashita, S.; Taniyama, K.; Niwa, M.: Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor. J. Biol. Chem., 271, 10143–10148 (1996)
Walker, J.K.; Gainetdinov, R.R.; Feldman, D.S.; McFawn, P.K.; Caron, M.G.; Lefkowitz, R.J.; Premont, R.T.; Fisher, J.T.: G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation. Am. J. Physiol., 286, L312–319 (2004)
Fraga, S.; Jose, P.A.; Soares-da-Silva, P.: Involvement of G protein-coupled receptor kinase 4 and 6 in rapid desensitization of dopamine D1 receptor in rat IEC-6 intestinal epithelial cells. Am. J. Physiol., 287, R772–779 (2004)
Ghadessy, R.S.; Willets, J.M.; Kelly, E.: G protein-coupled receptor kinase 6 (GRK6) selectively regulates endogenous secretin receptor responsiveness in NG108-15 cells. Br. J. Pharmacol., 138, 660–670 (2003)
Penela, P.; Ribas, C.; Mayor, F.: Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cell. Signal., 15, 973–981 (2003)
Oyama, N.; Urasawa, K.; Kaneta, S.; Sakai, H.; Saito, T.; Takagi, C.; Yoshida, I.; Kitabatake, A.; Tsutsui, H.: Chronic β-adrenergic receptor stimulation enhances the expression of G-protein coupled receptor kinases, GRK2 and GRK5, in both the heart and peripheral lymphocytes. Circ. J., 69, 987–990 (2005)
Keys, J.R.; Zhou, R.H.; Harris, D.M.; Druckman, C.A.; Eckhart, A.D.: Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gimediated signaling. Circulation, 112, 1145–1153 (2005)
Simon, V.; Robin, M.T.; Legrand, C.; Cohen-Tannoudji, J.: Endogenous G protein-coupled receptor kinase 6 triggers homologous β-adrenergic receptor desensitization in primary uterine smooth muscle cells. Endocrinology, 144, 3058–3066 (2003)
Voigt, C.; Holzapfel, H.P.; Paschke, R.: Decreased expression of G-protein coupled receptor kinase 2 in cold thyroid nodules. Exp. Clin. Endocrinol. Diabetes, 113, 102–106 (2005)
Vatter, P.; Stoesser, C.; Samel, I.; Gierschik, P.; Moepps, B.: The variable Cterminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain. FEBS J., 272, 6039–6051 (2005)
Picascia, A.; Capobianco, L.; Iacovelli, L.; De Blasi, A.: Analysis of differential modulatory activities of GRK2 and GRK4 on Gaq-coupled receptor signaling. Methods Enzymol., 390, 337–353 (2004)
Kohout, T.A.; Lefkowitz, R.J.: Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol. Pharmacol., 63, 9–18 (2003)
Willets, J.M.; Mistry, R.; Nahorski, S.R.; Challiss, R.A.: Specificity of G protein-coupled receptor kinase 6-mediated phosphorylation and regulation of single-cell M3 muscarinic acetylcholine receptor signaling. Mol. Pharmacol., 64, 1059–1068 (2003)
Neve, K.A.: Novel features of G protein-coupled receptor kinase 4. Mol. Pharmacol., 69, 673–676 (2006)
Zhu, H.; Lu, Y.; Wang, X.; Treiber, F.A.; Harshfield, G.A.; Snieder, H.; Dong, Y.: The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins. Am. J. Hypertens., 19, 61–66 (2006)
Wang, Y.; Li, B.; Zhao, W.; Liu, P.; Zhao, Q.; Chen, S.; Li, H.; Gu, D.: Association study of G protein-coupled receptor kinase 4 gene variants with essential hypertension in northern Han Chinese. Ann. Hum. Genet., 70, 778–783 (2006)
Premont, R.T.; Gainetdinov, R.R.: Physiological roles of G protein-coupled receptor kinases and arrestins. Annu. Rev. Physiol., 69, 511–534 (2007)
Ribas, C.; Penela, P.; Murga, C.; Salcedo, A.; Garcia-Hoz, C.; Jurado-Pueyo, M.; Aymerich, I.; Mayor, F.: The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling. Biochim. Biophys. Acta, 1768, 913–922 (2007)
Fraga, S.; Luo, Y.; Jose, P.; Zandi-Nejad, K.; Mount, D.B.; Soares-da-Silva, P.: Dopamine D1-like receptor-mediated inhibition of Cl/HCO3-exchanger activity in rat intestinal epithelial IEC-6 cells is regulated by G protein-coupled receptor kinase 6 (GRK 6). Cell Physiol. Biochem., 18, 347–360 (2006)
Lodowski, D.T.; Tesmer, V.M.; Benovic, J.L.; Tesmer, J.J.: The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs. J. Biol. Chem., 281, 16785–16793 (2006)
Parameswaran, N.; Pao, C.S.; Leonhard, K.S.; Kang, D.S.; Kratz, M.; Ley, S.C.; Benovic, J.L.: Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFκB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. J. Biol. Chem., 281, 34159–34170 (2006)
rawaka, S.; Wada, M.; Goto, S.; Karube, H.; Sakamoto, M.; Ren, C.H.; Koyama, S.; Nagasawa, H.; Kimura, H.; Kawanami, T.; Kurita, K.; Tajima, K.; Daimon, M.; Baba, M.; Kido, T.; Saino, S.; Goto, K.; Asao, H.; Kitanaka, C.; Takashita, E.; Hongo, S.; Nakamura, T.; Kayama, T.; Suzuki, Y.; Kobayashi, K.; Kat, K.a.t.a.: The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinsons disease. J. Neurosci., 26, 9227–9238 (2006)
Yang, W.; Xia, S.: Mechanisms of regulation and function of G-proteincoupled receptor kinases. World J. Gastroenterol., 12, 7753–7757 (2006)3
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
(2009). G-Protein-coupled receptor kinase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 Transferases. Springer Handbook of Enzymes, vol S3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85699-3_16
Download citation
DOI: https://doi.org/10.1007/978-3-540-85699-3_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-85698-6
Online ISBN: 978-3-540-85699-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)