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Relating Discontinuous Cardiac Electrical Activity to Mesoscale Tissue Structures: Detailed Image Based Modeling

  • Conference paper
Functional Imaging and Modeling of the Heart (FIMH 2007)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 4466))

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Abstract

We relate aspects of discontinuous cardiac activation to the mesoscale myocardial structural feature of interlaminae clefts or cleavage planes. Specialized numerical and computational procedures have been developed for modeling cardiac activation which accounts for detailed myocardial geometric structures derived from specific tissue samples. This modeling allows both study and analysis of the effects of cleavage planes and other structural barriers to myocardial current flow. The results show that mesoscale discontinuities significantly affect the formation of virtual electrodes, and can result in discontinuous activation with midwall pacing.

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Author information

Authors and Affiliations

  1. Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

    Mark L. Trew, Bruce H. Smaill & Andrew J. Pullan

  2. Department of Physiology,  

    Bruce H. Smaill

  3. Department of Engineering Science,  

    Andrew J. Pullan

Authors
  1. Mark L. Trew
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  2. Bruce H. Smaill
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  3. Andrew J. Pullan
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Editor information

Frank B. Sachse Gunnar Seemann

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© 2007 Springer Berlin Heidelberg

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Trew, M.L., Smaill, B.H., Pullan, A.J. (2007). Relating Discontinuous Cardiac Electrical Activity to Mesoscale Tissue Structures: Detailed Image Based Modeling. In: Sachse, F.B., Seemann, G. (eds) Functional Imaging and Modeling of the Heart. FIMH 2007. Lecture Notes in Computer Science, vol 4466. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72907-5_23

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  • DOI: https://doi.org/10.1007/978-3-540-72907-5_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-72906-8

  • Online ISBN: 978-3-540-72907-5

  • eBook Packages: Computer ScienceComputer Science (R0)

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