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Identification of Candidates and Selection Criteria

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Book cover Liver Radioembolization with 90Y Microspheres

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

The liver is the most frequent site of metastases as a result of the portal circulation and up to 60%-80% of patients with a history of colorectal carcinoma, pancreas carcinoma, breast cancer or other tumor types will develop metastases within the liver during the follow-up period [1]. There is no doubt that surgical resection of these metastases is the only potential curative option for these patients and is therefore considered as gold standard. However, due to anatomic or technical reasons or simple inoperability, only 20% of patients are suitable candidates for resection

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References

  1. Salem R, Thurston KG (2006) Radioembolization with 90Yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: technical and methodologic considerations. J Vasc Interv Radiol 17:1251–1278

    Article  PubMed  Google Scholar 

  2. Abdalla EK, Vauthey JN, Ellis LM et al (2004) Recurrence and outcomes following hepatic resection, radio-frequency ablation, and combined resection/ablation for colorectal liver metastases. Ann Surg 239:818–825; discussion 825-817

    Article  PubMed  Google Scholar 

  3. Goldberg RM, Hurwitz HI, Fuchs CS (2006) The role of targeted therapy in the treatment of colorectal cancer. Clin Adv Hematol Oncol 4 Suppl 17:1–12

    Google Scholar 

  4. Llovet JM (2005) Updated treatment approach to hepatocellular carcinoma. J Gastroenterol 40:225–235

    Article  PubMed  Google Scholar 

  5. Lewandowski RJ, Thurston KG, Goin JE et al (2005) 90Y microsphere (TheraSphere) treatment for unresectable colorectal cancer metastases of the liver: response to treatment at targeted doses of 135-150 Gy as measured by [18F]fluorodeoxyglucose positron emission tomography and computed tomographic imaging. J Vasc Interv Radiol 16:1641–1651

    PubMed  Google Scholar 

  6. Murthy R, Nunez R, Szklaruk J et al (2005) Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications. Radiographies 25 Suppl l:S41–55

    Article  Google Scholar 

  7. Salem R, Lewandowski RJ, Atassi B et al (2005) Treatment of unresectable hepatocellular carcinoma with use of 90Y microspheres (TheraSphere): safety, tumor response, and survival. J Vasc Interv Radiol 16:1627–1639

    PubMed  Google Scholar 

  8. Goin JE, Salem R, Carr BI et al (2005) Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities. J Vasc Interv Radiol 16:205–213

    PubMed  Google Scholar 

  9. Goin JE, Salem R, Carr BI et al (2005) Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: a risk-stratification analysis. J Vasc Interv Radiol 16:195–203

    PubMed  Google Scholar 

  10. Salem R, Lewandowski R, Roberts C et al (2004) Use of Yttrium-90 glass microspheres (TheraSphere) for the treatment of unresectable hepatocellular carcinoma in patients with portal vein thrombosis. J Vasc Interv Radiol 15:335–345

    PubMed  Google Scholar 

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© 2008 Springer-Verlag Berlin Heidelberg

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Hoffmann, RT., Jakobs, T.F., Reiser, M.F. (2008). Identification of Candidates and Selection Criteria. In: Bilbao, J.I., Reiser, M.F. (eds) Liver Radioembolization with 90Y Microspheres. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35423-9_2

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  • DOI: https://doi.org/10.1007/978-3-540-35423-9_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-35421-5

  • Online ISBN: 978-3-540-35423-9

  • eBook Packages: MedicineMedicine (R0)

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