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Photoplethysmography Imaging and Common Optical Hybrid Imaging Modalities

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Multi-Modality Imaging

Abstract

Due to their obvious advantages, active and passive optoelectronic sensor concepts for monitoring cardiorespiratory vital signs and detection of rhythmical phenomena in dermal blood perfusion are being investigated by various biomedical groups, particularly their camera-based variants. Such methods are noninvasive and contactless, and allow spatially resolved skin perfusion studies.

This chapter presents one of these medical imaging modalities (developed by and clinically tested at RWTH Aachen University), i.e., active photoplethysmography imaging (PPGI) for the mapping of dermal blood perfusion dynamics. PPGI is an enhancement of the classical photoplethysmography and pulse oximetry (SpO2) and describes the remote “opto-electronical measurement of arterial and/or venous blood volume changes”. Approved algorithms from these established methods, e.g., algorithms that extract the heart rate, heart rate variability, respiratory rate, and/or pulse wave form-related stress/pain signals, can easily be adapted to PPGI. This remote monitoring technique allows measurement of body signals without contact (unobtrusive) and with spatial resolution; moreover, it can be adapted to specific measurement scenarios, such as the monitoring of neonates and acquiring vital information from within the area of a wound.

Selected medical applications have been validated by our group using the PPGI technology in a stand-alone or hybrid camera configuration. Although these preliminary results are promising, additional research and development is necessary (especially for the detection and elimination of movement artifacts) before this novel technology can be transferred into a standardized clinical application.

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References

  1. C.H. Cartwright, J. Opt. Soc. Am. 20(2), 81 (1930)

    Article  Google Scholar 

  2. H. Haxthausen, Br. J. Dermatol. 45(12), 506 (1933)

    Article  Google Scholar 

  3. K. Matthes, Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. 179(6), 698 (1935)

    Article  CAS  Google Scholar 

  4. H. Molitor, M. Kniazuk, J. Pharmacol. Exp. Ther. 57(1), 6 (1936)

    Google Scholar 

  5. A.B. Hertzman, C.R. Spealman, Am. J. Physiol. 119, 334 (1937)

    Google Scholar 

  6. A.B. Hertzman, Am. J. Physiol. 124, 329 (1938)

    Google Scholar 

  7. V. Blazek, U. Schultz-Ehrenburg, in Frontiers in Computer-Aided Visualization of Vascular Functions. Proceedings 7th Int. Symposium CNVD ’97, ed. by V. Blazek, U. Schultz-Ehrenburg, chap. 1 (VDI Verlag, Düsseldorf, 1988), pp. 1–5

    Google Scholar 

  8. T. Wu, V. Blazek, H.J. Schmitt, in Proceedings of SPIE, vol. 4163, ed. by A.V. Priezzhev, P.A. Oberg (International Society for Optics and Photonics, Bellingham, 2000), p. 62

    Google Scholar 

  9. V. Blazek, T. Wu, D. Hoelscher, in Proceedings of SPIE, vol. 3923, ed. by A.V. Priezzhev, T. Asakura (International Society for Optics and Photonics, Bellingham, 2000), pp. 2–9

    Google Scholar 

  10. M.Z. Poh, D.J. McDuff, R.W. Picard, IEEE Trans. Biomed. Eng. 58(1), 7 (2011)

    Article  Google Scholar 

  11. L. Tarassenko, M. Villarroel, A. Guazzi, J. Jorge, D.A. Clifton, C. Pugh, Physiol. Meas. 35(5), 807 (2014)

    Article  CAS  Google Scholar 

  12. M. Kumar, A. Veeraraghavan, A. Sabharwal, Biomed. Opt. Express 6(5), 1565 (2015)

    Article  Google Scholar 

  13. M. van Gastel, S. Stuijk, G. de Haan, IEEE Trans. Biomed. Eng. 62(5), 1425 (2015)

    Article  Google Scholar 

  14. D.J. McDuff, J.R. Estepp, A.M. Piasecki, E.B. Blackford, in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), vol. 2015 (IEEE, Piscataway, 2015), pp. 6398–6404

    Google Scholar 

  15. W. Wang, S. Stuijk, G. de Haan, IEEE Trans. Biomed. Eng. 62(2), 415 (2015)

    Article  Google Scholar 

  16. Y. Sun, N. Thakor, IEEE Trans. Biomed. Eng. 63(3), 463 (2016)

    Article  Google Scholar 

  17. A. Trumpp, J. Schell, H. Malberg, S. Zaunseder, Curr. Dir. Biomed. Eng. 2(1), 199 (2016)

    Google Scholar 

  18. A.K. Abbas, K. Heimann, V. Blazek, T. Orlikowsky, S. Leonhardt, Infrared Phys. Technol. 55(6), 538 (2012)

    Article  Google Scholar 

  19. C.B. Pereira, M. Czaplik, N. Blanik, R. Rossaint, V. Blazek, S. Leonhardt, Biomed. Opt. Express 5(4), 1075 (2014)

    Article  Google Scholar 

  20. N. Blanik, K.A. Abbas, B. Venema, V. Blazek, S. Leonhardt, in Innovations and Applications of Monitoring Perfusion, Oxygenation and Ventilation (Yale University, New Haven, 2012)

    Google Scholar 

  21. N. Blanik, A.K. Abbas, B. Venema, V. Blazek, S. Leonhardt, J. Biomed. Opt. 19(1), 016012 (2014)

    Article  Google Scholar 

  22. N. Blanik, M. Paul, V. Blazek, S. Leonhardt, in 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), vol. 2015 (IEEE, Piscataway, 2015), pp. 2383–2386

    Google Scholar 

  23. V. Blazek, U. Schultz-Ehrenburg, Quantitative Photoplethysmography: Basic Facts and Examination Tests for Evaluating Peripheral Vascular Functions (VDI-Verlag, Düsseldorf, 1996)

    Google Scholar 

  24. B. Venema, N. Blanik, V. Blazek, H. Gehring, A. Opp, S. Leonhardt, IEEE Trans. Biomed. Eng. 59(7), 2003 (2012)

    Article  Google Scholar 

  25. M. Huelsbusch, Ein bildgestütztes, funktionelles Verfahren zur optoelektreonischen Erfassung der Hautperfusion (An image-based and functional technik for the optoelectronical assessment of skin perfusion). Ph.D. thesis, RWTH Aachen University, Aachen, 2008

    Google Scholar 

  26. N. Blanik, in Studies in Skin Perfusion Dynamics – Photoplethysmography and Its Applications in Medical Diagnostics, ed. by V. Blazek, V.J. Kumar, S. Leonhardt, M.M. Rao (Springer, New Delhi, 2016)

    Google Scholar 

  27. V. Blazek, Communications 1, 5 (2011)

    Google Scholar 

  28. M.H. Yang, N. Ahuja, Face Detection and Gesture Recognition for Human-Computer Interaction (Springer US, New York, 2001)

    Book  Google Scholar 

  29. B. Jaehne, Digital Image Processing, 6th edn. (Springer, Berlin, 2015)

    Google Scholar 

  30. D. Forsyth, J. Ponce, Computer Vision: A Modern Approach, 2nd edn. (Prentice Hall, Upper Saddle River, 2012)

    Google Scholar 

  31. M. Paul, N. Blanik, V. Blazek, S. Leonhardt, in Proc. of SPIE, vol. 9534, ed. by F. Meriaudeau, O. Aubreton (International Society for Optics and Photonics, Bellingham, 2015), pp. 95340P1–95340P7

    Google Scholar 

  32. F. Massanes, M. Cadennes, J.G. Brankov, J. Electron. Imaging 20(3), 1 (2011)

    Article  Google Scholar 

  33. A. Gyaourova, C. Kamath, S.C. Cheung, Block matching for object tracking. Tech. rep., Lawrence Livermore National Laboratory, 2003

    Google Scholar 

  34. C. Mayntz, J.M. Frahm, T. Aach, G. Schmitz, in Mustererkennung 2000 (Pattern Recognition 2000), ed. by G. Sommer, N. Krueger, C. Perwass (Springer, Berlin, 2000), pp. 123–130

    Chapter  Google Scholar 

  35. G.A. Jones, Comput. Vis. Image Underst. 65(1), 57 (1997)

    Article  Google Scholar 

  36. B. Heisele, Objektdetektion in Straßenverkehrsszenen durch Auswertung von Farbbildfolgen (Analysis of video sequences for object detection in scenes of road traffic). Ph.D. thesis, University Stuttgart, VDI-Verlag, Düsseldorf, 1998

    Google Scholar 

  37. S.g. Wei, L. Yang, Z. Chen, Z.f. Liu, Procedia Eng. 15, 3471 (2011)

    Google Scholar 

  38. B.K.P. Horn, B.G. Schunck, Artif. Intell. 17(1–3), 185 (1981)

    Article  Google Scholar 

  39. B.D. Lucas, T. Kanade, in Proceedings of the 7th International Joint Conference on Artificial Intelligence - Volume 2 (Morgan Kaufmann Publishers, Burlington, 1981), pp. 674–679

    Google Scholar 

  40. C. Tomasi, T. Kanade, Detection and tracking of point features. Tech. rep., College of Engineering, Computing and Applied Sciences, Clemson University, Technical Report CMU-CS-91–132, Clemson, 1991

    Google Scholar 

  41. P. Viola, M. Jones, Int. J. Comput. Vis. 4, 51 (2001)

    Google Scholar 

  42. D.G. Lowe, Method and apparatus for identifying scale invariant features in an image and use of same for locating an object in an image (2000)

    Google Scholar 

  43. H. Bay, T. Tuytelaars, L. Van Gool, in ECCV 2006: Computer Vision – ECCV 2006, ed. by A. Leonardis, H. Bischof, A. Pinz. Lecture Notes in Computer Science (Springer, Berlin, 2006), pp. 404–417

    Google Scholar 

  44. G. Schwarzenberg, Objektverfolgung mit Partikel-Filter (Object tracking with a particle filter). Ph.D. thesis, University Karlsruhe, Karlsruhe, 2005

    Google Scholar 

  45. B. Ristic, S. Arulampalam, N. Gordon, Beyond the Kalman Filter: Particle Filters for Tracking Applications (Artech Print on Demand, Norwood, 2004)

    Google Scholar 

  46. R. Kalman, Trans. ASME J. Basic Eng. 82(Series D), 35 (1960)

    Google Scholar 

  47. E.V. Cuevas, D. Zaldivar, R. Rojas, Kalman filter for vision tracking. Tech. rep., Technical Report B 05-12 FU Berlin, 2005

    Google Scholar 

  48. Y. Cheng, IEEE Trans. Pattern Anal. Mach. Intell. 17(8), 790 (1995)

    Article  Google Scholar 

  49. O.P. Hornstein, G. Heyer, B. Langenstein, Acta Derm. Venereol. Suppl. 144, 146 (1989)

    CAS  Google Scholar 

  50. C. Blazek, V. Blazek, in Studies in Skin Perfusion Dynamics – Photoplethysmography and Its Applications in Medical Diagnostics, ed. by V. Blazek, V.J. Kumar, S. Leonhardt, M.M. Rao (Springer, New Delhi, 2016)

    Google Scholar 

  51. K. Wardell, A. Jakobsson, G. Nilsson, IEEE Trans. Biomed. Eng. 40(4), 309 (1993)

    Article  CAS  Google Scholar 

  52. K.J. Dierolf, Nichtinvasive Methoden zur Differenzierung dermaler melanozyterer Laesionen – klinische ABCD-Regel, Dermatoskopie, Laser-Doppler-Fluxmetrie (Noninvasive methods for differentiation of dermal melanocytic lesions – clinical ABCD rule, dermatoscopy, Laser Do. Ph.D. thesis, University Tuebingen, Tuebingen, 2007

    Google Scholar 

  53. M. Juenger, A. Steins, B. Schlagenhauff, G. Rassner, Hautarzt 50(12), 848 (1999)

    Article  Google Scholar 

  54. N. Blanik, K. Heimann, C. Pereira, M. Paul, V. Blazek, B. Venema, T. Orlikowsky, S. Leonhardt, Biomed. Eng./Biomed. Tech. 61(6), 631 (2016)

    Google Scholar 

  55. V. Blazek, N. Blanik, C.R. Blazek, M. Paul, C. Pereira, M. Koeny, B. Venema, S. Leonhardt, Anesth. Analg. 124(1), 104 (2017)

    Article  Google Scholar 

  56. J.W. Severinghaus, Anesth. Analg. 105(6), S1 (2007)

    Article  Google Scholar 

  57. V. Blazek, M. Hülsbusch, M. Herzog, Biomed. Tech. 52(B), 1 (2007)

    Google Scholar 

  58. N. Blanik, Konzept und Realisierung eines kontaktlosen Messsystems für die ortsaufgelöste Erfassung der Sauerstoffsättigung der Haut (Concept development and implementation of a contactless measurement system for the spatially resolved assessment of oxygen saturation). Ph.D. thesis, RWTH Aachen University, Aachen, 2010

    Google Scholar 

  59. N. Blanik, B. Venema, V. Blazek, S. Leonhardt, Clin. Technol. 44, 5 (2014)

    Google Scholar 

  60. C.H. Blackley, Hay Fever: Its Causes, Treatment and Effective Prevention: Experimental Researches, 2nd edn. (Baillière, Tindall & Cox, London, 1880)

    Google Scholar 

  61. B. Przybilla, K.C. Bergmann, J. Ring, Praktische allergologische Diagnostik (Allergy Diagnostic), 1st edn. (Steinkopff-Verlag, Darmstadt, 2000)

    Google Scholar 

  62. F. Ruëff, K.C. Bergmann, K. Brockow, T. Fuchs, A. Grübl, K. Jung, L. Klimek, H. Müsken, O. Pfaar, B. Przybilla, H. Sitter, W. Wehrmann, German Society for Allergology and Clinical Immunology. Pneumologie 65(08), 484 (2011)

    PubMed  Google Scholar 

  63. H. Pijnenborg, L. Nilsson, S. Dreborg, Allergy 51(11), 782 (1996)

    Article  CAS  Google Scholar 

  64. A.M. Opazo Saez, F. Mosel, J. Nurnberger, U. Rushentsova, M. Gossl, A. Mitchell, R.F. Schafers, T. Philipp, R.R. Wenzel, Br. J. Clin. Pharmacol. 59(5), 511 (2005)

    Article  Google Scholar 

  65. C.F. Clough, A.R. Bennett, M.K. Church, Br. J. Dermatol. 138(5), 806 (1998)

    Article  CAS  Google Scholar 

  66. T.W. Ridler, S. Calvard, IEEE Trans. Syst. Man Cybern. 8, 630 (1978)

    Article  Google Scholar 

  67. C. Janus, Funktionelle Erkennung und Vermessung von Ulcera und allergischen Hautreaktionen in Einzelaufnahmen und PPGI Bildsequenzen (Functional detection and measurement of ulcers and allergic skin reactions in images and PPGI video sequences). Ph.D. thesis, RWTH Aachen University, Aachen, 2008

    Google Scholar 

  68. V. Blazek, in Studies in Skin Perfusion Dynamics – Photoplethysmography and Its Applications in Medical Diagnostics, ed. by V. Blazek, V.J. Kumar, S. Leonhardt, M.M. Rao (Springer, New Delhi, 2016)

    Google Scholar 

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Author information

Authors and Affiliations

  1. Chair for Medical Information Technology, Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany

    Vladimir Blazek, Stephan Dahlmanns, Carina Barbosa Pereira, Xinchi Yu, Nikolai Blanik & Steffen Leonhardt

  2. Czech Institute of Informatics, Robotics and Cybernetics (CIIRC), Czech Technical University in Prague, Prague, Czech Republic

    Vladimir Blazek

  3. The Private Clinic of Dermatology, Haut im Zentrum, Zurich, Switzerland

    Claudia Rosa Blazek

Authors
  1. Vladimir Blazek
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  2. Stephan Dahlmanns
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  3. Carina Barbosa Pereira
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  4. Xinchi Yu
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  5. Nikolai Blanik
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  7. Claudia Rosa Blazek
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Correspondence to Vladimir Blazek .

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Editors and Affiliations

  1. Graduate Program on Health Technology (PPGTS), Pontifical Catholic University of Paraná – PUCPR, Curitiba, Paraná, Brazil

    Mauren Abreu de Souza

  2. Federal University of Technology – Paraná (UTFPR), Curitiba, Paraná, Brazil

    Humberto Remigio Gamba

  3. Institute of Computing, University of Campinas, Campinas, São Paulo, Brazil

    Helio Pedrini

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Blazek, V. et al. (2018). Photoplethysmography Imaging and Common Optical Hybrid Imaging Modalities. In: Abreu de Souza, M., Remigio Gamba, H., Pedrini, H. (eds) Multi-Modality Imaging. Springer, Cham. https://doi.org/10.1007/978-3-319-98974-7_2

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