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Ocular Perfusion Pressure as a Risk Factor

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Biophysical Properties in Glaucoma

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Abstract

The contribution of vascular deficits in glaucomatous optic neuropathy is based upon a recent increase in clinical data on vascular dysregulation involved in glaucoma pathology and was reflected by the World Glaucoma Association consensus on ocular blood flow in glaucoma. Inadequate or unstable ocular blood supply causes ischemic damage or reperfusion injury to the optic nerve head and axons. Ocular blood flow is dependent on perfusion pressure in the absence of vascular autoregulation. While in healthy subjects, autoregulation has been to maintain constant blood flow over a wide range of perfusion pressures.

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Authors and Affiliations

  1. Eye Clinic, Lithuanian University of Health Sciences, Kaunas, Lithuania

    Lina Siaudvytyte

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  1. Lina Siaudvytyte
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Correspondence to Lina Siaudvytyte .

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Editors and Affiliations

  1. Lithuanian University of Health Sciences, Kaunas, Lithuania

    Ingrida Januleviciene

  2. Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, USA

    Alon Harris

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Siaudvytyte, L. (2019). Ocular Perfusion Pressure as a Risk Factor. In: Januleviciene, I., Harris, A. (eds) Biophysical Properties in Glaucoma. Springer, Cham. https://doi.org/10.1007/978-3-319-98198-7_3

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  • DOI: https://doi.org/10.1007/978-3-319-98198-7_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98197-0

  • Online ISBN: 978-3-319-98198-7

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