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The Use and Efficacy of Transcranial Direct Current Stimulation in Individuals with Neurodegenerative Dementias

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Abstract

This chapter reviews existing and ongoing research related to the use of transcranial direct current stimulation (tDCS) as a potential cognitive enhancement intervention in cognitively impaired individuals across a range of neurodegenerative diseases including Alzheimer’s type dementia (DAT), Parkinson’s disease dementia (PDD) or dementia with Lewy bodies (DLB), frontotemporal dementia – behavioral variant (bvFTD), and primary progressive aphasia (PPA). Methodological information, including treatment montage and session structure, efficacy/outcome, and other tDCS related details are provided for each study. While still relatively early in the clinical translation phase, tDCS appears to hold some promise in these clinical samples but considerably more work is needed to identify optimal treatment parameters as well as how these may be affected by disease severity.

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Authors and Affiliations

  1. Department of Mental Health Services, Veterans Affairs Ann Arbor Healthcare Systems, Ann Arbor, MI, USA

    Annalise Rahman-Filipiak, Jaclyn M. Reckow & Benjamin M. Hampstead

  2. Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA

    Annalise Rahman-Filipiak, Jaclyn M. Reckow & Benjamin M. Hampstead

  3. Center for Cognitive Aging and Memory (CAM), McKnight Brain Institute, Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA

    Adam J. Woods

  4. Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany

    Michael A. Nitsche

  5. University Medical Hospital Bergmannsheil, Bochum, Germany

    Michael A. Nitsche

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  1. Annalise Rahman-Filipiak
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  2. Jaclyn M. Reckow
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  3. Adam J. Woods
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Correspondence to Benjamin M. Hampstead .

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Editors and Affiliations

  1. MJHS Institute for Innovation in Palliative Care, New York, NY, USA

    Helena Knotkova

  2. Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany

    Michael A. Nitsche

  3. Department of Biomedical Engineering, The City College of New York, New York, NY, USA

    Marom Bikson

  4. Center for Cognitive Aging and Memory (CAM), McKnight Brain Institute, Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA

    Adam J. Woods

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Rahman-Filipiak, A., Reckow, J.M., Woods, A.J., Nitsche, M.A., Hampstead, B.M. (2019). The Use and Efficacy of Transcranial Direct Current Stimulation in Individuals with Neurodegenerative Dementias. In: Knotkova, H., Nitsche, M., Bikson, M., Woods, A. (eds) Practical Guide to Transcranial Direct Current Stimulation. Springer, Cham. https://doi.org/10.1007/978-3-319-95948-1_16

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