Abstract
The membrane proteins are still the “Wild West” of structural biology. Although more and more membrane proteins structures are determined, their functioning is still difficult to investigate because they are fully functional only in the membranous environments. Several specific methodologies were developed to investigate various aspects of their cellular life but still they are challenging for computational methods. In this chapter we summarize the efforts made on elucidation the structural and dynamical properties of different types of membrane proteins emphasizing on those computational methods which were designed and employed particularly to study membrane proteins including their interactions in complex membranous systems. This chapter was updated in all subsections compared to the 1st edition.
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Latek, D. et al. (2019). Modeling of Membrane Proteins. In: Liwo, A. (eds) Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes. Springer Series on Bio- and Neurosystems, vol 8. Springer, Cham. https://doi.org/10.1007/978-3-319-95843-9_12
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