Abstract
Adults with congenital heart disease represent a small but growing population of patients presenting for cardiac rehabilitation. An approach to clinical assessment of these patients prior to commencing cardiac rehabilitation is discussed. Methods to evaluate exercise capacity are reviewed. Aerobic capacity is significantly reduced in adult congenital heart disease patients and is related to prognosis. Exercise prescription based on the FITT principle is discussed. Benefits of moderate continuous aerobic training versus high-intensity interval training are compared. Testing muscular strength and endurance are described, and resistance training in congenital heart disease is discussed. Evidence for exercise training on improving exercise capacity in congenital heart disease is reviewed. Spontaneous physical activity is reduced, with most adult congenital patients not achieving the World Health Organization’s (W.H.O.) recommendations for daily physical activity and correspondingly having excessive sedentary time. Comprehensive cardiac rehabilitation programs should include formal exercise training as well as physical activity counseling to improve exercise capacity, reduce the risk of coronary artery disease, and ultimately reduce morbidity and mortality in patients with congenital heart disease.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Pinto NM, Marino BS, Wernovsky G, de Ferranti SD, Walsh AZ, Laronde M, et al. Obesity is a common comorbidity in children with congenital and acquired heart disease. Pediatrics. 2007;120(5):e1157–e64.
Lunt D, Briffa T, Briffa NK, Ramsay J. Physical activity levels of adolescents with congenital heart disease. Aust J Physiother. 2003;49(1):43–50.
Reybrouck T, Mertens L. Physical performance and physical activity in grown-up congenital heart disease. Eur J Cardiovasc Prev Rehabil. 2005;12(5):498–502.
Duppen N, Etnel JR, Spaans L, Takken T, van den Berg-Emons RJ, Boersma E, et al. Does exercise training improve cardiopulmonary fitness and daily physical activity in children and young adults with corrected tetralogy of Fallot or Fontan circulation? A randomized controlled trial. Am Heart J. 2015;170(3):606–14.
Gatzoulis M, Balaji S, Webber S, Siu S, Hokanson J, Poile C, et al. Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study. Lancet. 2000;356:975–81.
Baumgartner H, Bonhoeffer P, De Groot NM, de Haan F, Deanfield JE, Galie N, et al. ESC Guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J. 2010;31(23):2915–57.
Thompson PD, Arena R, Riebe D, Pescatello LS. ACSM’s new preparticipation health screening recommendations from ACSM’s guidelines for exercise testing and prescription. Curr Sports Med Rep. 2013;12(4):215–7.
American College of Sports Medicine. ACSM’s guidelines for exercise testing and prescription. 10th ed. Philadelphia: Lippincott Williams & Wilkins; 2017.
Rhodes J, Tikkanen AU, Jenkins KJ. Exercise testing and training in children with congenital heart disease. Circulation. 2010;122(19):1957–67.
Buber J, Rhodes J. Exercise physiology and testing in adult patients with congenital heart disease. Heart Fail Clin. 2014;10(1):23–33.
Diller G-P, Dimopoulos K, Okonko D, Uebing A, Broberg CS, Babu-Narayan S, et al. Heart rate response during exercise predicts survival in adults with congenital heart disease. J Am Coll Cardiol. 2006;48(6):1250–6.
Kempny A, Dimopoulos K, Uebing A, Moceri P, Swan L, Gatzoulis MA, et al. Reference values for exercise limitations among adults with congenital heart disease. Relation to activities of daily life—single centre experience and review of published data. Eur Heart J. 2011;33(11):1386–96.
Inuzuka R, Diller G-P, Borgia F, Benson L, Tay EL, Alonso-Gonzalez R, et al. Comprehensive use of cardiopulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term. Circulation. 2012;125(2):250–9.
Balady GJ, Arena R, Sietsema K, Myers J, Coke L, Fletcher GF, et al. Clinician’s guide to cardiopulmonary exercise testing in adults. Circulation. 2010;122(2):191–225.
Dempsey JA, Wagner PD. Exercise-induced arterial hypoxemia. J Appl Physiol. 1999;87(6):1997–2006.
Ross R, Blair SN, Arena R, Church TS, Després J-P, Franklin BA, et al. Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association. Circulation. 2016;134:e653.
Diller G, Dimopoulus K, Okonko D, Li W, Babu-Narayan S, Broberg C, et al. Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication. Circulation. 2005;112:828–35.
Giardini A, Specchia S, Tacy TA, Coutsoumbas G, Gargiulo G, Donti A, et al. Usefulness of cardiopulmonary exercise to predict long-term prognosis in adults with repaired tetralogy of Fallot. Am J Cardiol. 2007;99(10):1462–7.
Takken T, Giardini A, Reybrouck T, Gewillig M, Hövels-Gürich H, Longmuir P, et al. Recommendations for physical activity, recreation sport, and exercise training in paediatric patients with congenital heart disease: a report from the Exercise, Basic & Translational Research Section of the European Association of Cardiovascular Prevention and Rehabilitation, the European Congenital Heart and Lung Exercise Group, and the Association for European Paediatric Cardiology. Eur J Prev Cardiol. 2012;19(5):1034–65.
Rhodes J. Serial exercise testing in patients with congenital heart disease. J Cardiol Ther. 2015;2(1):250–4.
Duppen N, Takken T, Hopman M, At H, Dulfer K, Utens E, et al. Systemic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol. 2013;168:1779–87.
Buys R, Cornelissen V, Van De Bruaene A, Stevens A, Coeckelberghs E, Onkelinx S, et al. Measures of exercise capacity in adults with congenital heart disease. Int J Cardiol. 2011;153(1):26–30.
Johnson JT, Yetman AT. Cardiopulmonary exercise testing in adults with congenital heart disease. Prog Pediatr Cardiol. 2012;34(1):47–52.
Müller J, Böhm B, Semsch S, Oberhoffer R, Hess J, Hager A. Currently, children with congenital heart disease are not limited in their submaximal exercise performance. Eur J Cardiothorac Surg. 2013;43(6):1096–100.
Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol. 1986;60(6):2020–7.
Wasserman K. The anaerobic threshold measurement to evaluate exercise performance 1, 2. Am Rev Respir Dis. 1984;129(2P2):S35–40.
Mezzani A, Hamm LF, Jones AM, McBride PE, Moholdt T, Stone JA, et al. Aerobic exercise intensity assessment and prescription in cardiac rehabilitation: a joint position statement of the European Association for Cardiovascular Prevention and Rehabilitation, the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac Rehabilitation. Eur J Prev Cardiol. 2013;20(3):442–67.
Dimopoulos K, Okonko DO, Diller GP, Broberg CS, Salukhe TV, Babu-Narayan SV, et al. Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival. Circulation. 2006;113(24):2796–802.
Arena R, Myers J, Williams MA, Gulati M, Kligfield P, Balady GJ, et al. Assessment of functional capacity in clinical and research settings: a scientific statement from the American Heart Association Committee on Exercise, Rehabilitation, and Prevention of the Council on Clinical Cardiology and the Council on Cardiovascular Nursing. Circulation. 2007;116(3):329–43.
Clark AL, Gatzoulis MA, Redington AN. Ventilatory responses to exercise in adults after repair of tetralogy of Fallot. Br Heart J. 1995;73(5):445–9.
Fletcher GF, Ades PA, Kligfield P, Arena R, Balady GJ, Bittner VA, et al. Exercise standards for testing and training a scientific statement from the American Heart Association. Circulation. 2013;128(8):873–934.
Sutton NJ, Peng L, Lock JE, Lang P, Marx GR, Curran TJ, O’Neill JA, Picard ST, Rhodes J. Effect of pulmonary artery angioplasty on exercise function after repair of tetralogy of Fallot. Am Heart J. 2008;155(1):182–6.
Moalla W, Gauthier R, Maingourd Y, Ahmaidi S. Six-minute walking test to assess exercise tolerance and cardiorespiratory responses during training program in children with congenital heart disease. Int J Sports Med. 2005;26(9):756–62.
American Thoracic Society. ATS statement: guidelines for the six minute walk test. Am J Crit Care Med. 2002;166:111–7.
Rasekaba T, Lee A, Naughton M, Williams T, Holland A. The six-minute walk test: a useful metric for the cardiopulmonary patient. Intern Med J. 2009;39(8):495–501.
Williams MA, Haskell WL, Ades PA, Amsterdam EA, Bittner V, Franklin BA, et al. Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2007;116(5):572–84.
Van De Bruaene A, Claessen G, La Gerche A, Kung E, Marsden A, De Meester P, et al. Effect of respiration on cardiac filling at rest and during exercise in Fontan patients: a clinical and computational modeling study. Int J Cardiol Heart Vasc. 2015;9:100–8.
Kim PS, Mayhew JL, Peterson DF. A modified YMCA bench press test as a predictor of 1 repetition maximum bench press strength. J Strength Cond Res. 2002;16(3):440–5.
Fredriksen PM, Veldtman G, Hechter S, Therrien J, Chen A, Warsi MA, et al. Aerobic capacity in adults with various congenital heart diseases. Am J Cardiol. 2001;87(3):310–4.
Foster E, Graham TP Jr, Driscoll DJ, Reid GJ, Reiss JG, Russell IA, et al. Task force 2: special health care needs of adults with congenital heart disease. J Am Coll Cardiol. 2001;37(5):1176–83.
Deanfield J, Thaulow E, Warnes C, Webb G, Kolbel F, Hoffman A, et al. Management of grown up congenital heart disease. Eur Heart J. 2003;24(11):1035–84.
Reybrouck T, Bisschop A, Dumoulin M, van der Hauwaert LG. Cardiorespiratory exercise capacity after surgical closure of atrial septal defect is influenced by the age at surgery. Am Heart J. 1991;122(4 Pt 1):1073–8.
Winter MM, van der Bom T, de Vries LCS, Balducci A, Bouma BJ, Pieper PG, et al. Exercise training improves exercise capacity in adult patients with a systemic right ventricle: a randomized clinical trial. Eur Heart J. 2012;33(11):1378–85.
Driscoll DJ, Staats BA, Heise CT, Rice MJ, Puga FJ, Danielson GK, et al. Functional single ventricle: cardiorespiratory response to exercise. J Am Coll Cardiol. 1984;4(2):337–42.
Driscoll DJ, Durongpisitkul K. Exercise testing after the Fontan operation. Pediatr Cardiol. 1999;20(1):57–9; discussion 60.
Sietsema KE, Cooper D, Perloff JK, Rosove M, Child J, Canobbio M, et al. Dynamics of oxygen uptake during exercise in adults with cyanotic congenital heart disease. Circulation. 1986;73(6):1137–44.
Sterrett LE, Ebenroth ES, Query C, Ho J, Montgomery GS, Hurwitz RA, et al. Why exercise capacity does not improve after pulmonary valve replacement. Pediatr Cardiol. 2014;35(8):1395–402.
Greutmann M, Le TL, Tobler D, Biaggi P, Oechslin EN, Silversides CK, et al. Generalised muscle weakness in young adults with congenital heart disease. Heart. 2011;97(14):1164–8.
Giardini A, Specchia S, Coutsoumbas G, Donti A, Formigari R, Fattori R, et al. Impact of pulmonary regurgitation and right ventricular dysfunction on oxygen uptake recovery kinetics in repaired tetralogy of Fallot. Eur J Heart Fail. 2006;8(7):736–43.
Mercer-Rosa L, Ingall E, Zhang X, McBride M, Kawut S, Fogel M, et al. The impact of pulmonary insufficiency on the right ventricle: a comparison of isolated valvar pulmonary stenosis and tetralogy of Fallot. Pediatr Cardiol. 2015;36(4):796–801.
Sabate Rotes A, Johnson JN, Burkhart HM, Eidem BW, Allison TG, Driscoll DJ. Cardiorespiratory response to exercise before and after pulmonary valve replacement in patients with repaired tetralogy of Fallot: a retrospective study and systematic review of the literature. Congenit Heart Dis. 2015;10(3):263–70.
Derrick GP, Narang I, White PA, Kelleher A, Bush A, Penny DJ, et al. Failure of stroke volume augmentation during exercise and dobutamine stress is unrelated to load-independent indexes of right ventricular performance after the Mustard operation. Circulation. 2000;102(Suppl 3):Iii-154–9.
Graham TP Jr, Driscoll DJ, Gersony WM, Newburger JW, Rocchini A, Towbin JA. Task force 2: congenital heart disease. J Am Coll Cardiol. 2005;45(8):1326–33.
Driscoll DJ, Danielson GK, Puga FJ, Schaff HV, Heise CT, Staats BA. Exercise tolerance and cardiorespiratory response to exercise after the Fontan operation for tricuspid atresia or functional single ventricle. J Am Coll Cardiol. 1986;7(5):1087–94.
Takken T, Tacken MH, Blank AC, Hulzebos EH, Strengers JL, Helders PJ. Exercise limitation in patients with Fontan circulation: a review. J Cardiovasc Med (Hagerstown). 2007;8(10):775–81.
Paridon SM, Mitchell PD, Colan SD, Williams RV, Blaufox A, Li JS, et al. A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation. J Am Coll Cardiol. 2008;52(2):99–107.
Cordina RL, O'Meagher S, Karmali A, Rae CL, Liess C, Kemp GJ, et al. Resistance training improves cardiac output, exercise capacity and tolerance to positive airway pressure in Fontan physiology. Int J Cardiol. 2013;168(2):780–8.
McCall R, Humphrey R. Exercise training in a young adult late after a fontan procedure to repair single ventricle physiology. J Cardpulm Rehabil. 2001;21(4):227–30.
Minamisawa S, Nakazawa M, Momma K, Imai Y, Satomi G. Effect of aerobic training on exercise performance in patients after the Fontan operation. Am J Cardiol. 2001;88(6):695–8.
Moalla W, Maingourd Y, Gauthier R, Cahalin LP, Tabka Z, Ahmaidi S. Effect of exercise training on respiratory muscle oxygenation in children with congenital heart disease. Eur J Cardiovasc Prev Rehabil. 2006;13(4):604–11.
Opocher F, Varnier M, Sanders SP, Tosoni A, Zaccaria M, Stellin G, et al. Effects of aerobic exercise training in children after the Fontan operation. Am J Cardiol. 2005;95(1):150–2.
Budts W, Börjesson M, Chessa M, van Buuren F, Trindade PT, Corrado D, et al. Physical activity in adolescents and adults with congenital heart defects: individualized exercise prescription. Eur Heart J. 2013;34(47):3669–74.
Scherr J, Wolfarth B, Christle JW, Pressler A, Wagenpfeil S, Halle M. Associations between Borg’s rating of perceived exertion and physiological measures of exercise intensity. Eur J Appl Physiol. 2013;113(1):147–55.
Tomassoni TL, Galioto P, Vaccaro P, Vaccaro J. Effects of exercise training on exercise tolerance and cardiac output in children after repair of congenital heart disease. Sports Train Med Rehab. 1990;2:57–62.
Tomassoni TL. Role of exercise in the management of cardiovascular disease in children and youth. Med Sci Sports Exerc. 1996;28(4):406–13.
Rhodes J, Curran TJ, Camil L, Rabideau N, Fulton DR, Gauthier NS, et al. Impact of cardiac rehabilitation on the exercise function of children with serious congenital heart disease. Pediatrics. 2005;116(6):1339–45.
Bradley LM, Galioto FM Jr, Vaccaro P, Hansen DA, Vaccaro J. Effect of intense aerobic training on exercise performance in children after surgical repair of tetralogy of Fallot or complete transposition of the great arteries. Am J Cardiol. 1985;56(12):816–8.
Calzolari A, Turchetta A, Biondi G, Drago F, De Ranieri C, Gagliardi G, et al. Rehabilitation of children after total correction of tetralogy of Fallot. Int J Cardiol. 1990;28(2):151–8.
Galioto F, Romassoni T. Cardiac rehabilitation for children with heart disease. Med Exerc Nutr Health. 1992;1:272–80.
Galioto F, Tomassoni T. Exercise rehabilitation in congenital heart disease. Prog Pediatr Cardiol. 1993;2(3):50–4.
Guiraud T, Nigam A, Gremeaux V, Meyer P, Juneau M, Bosquet L. High-intensity interval training in cardiac rehabilitation. Sports Med. 2012;42(7):587–605.
Astorino TA, Allen RP, Roberson DW, Jurancich M. Effect of high-intensity interval training on cardiovascular function, VO2max, and muscular force. J Strength Condit Res. 2012;26(1):138–45.
Beauchamp MK, Nonoyama M, Goldstein RS, Hill K, Dolmage TE, Mathur S, et al. Interval versus continuous training in individuals with chronic obstructive pulmonary disease—a systematic review. Thorax. 2010;65(2):157–64.
Meyer K, Samek L, Schwaibold M, Westbrook S, Hajric R, Beneke R, et al. Interval training in patients with severe chronic heart failure: analysis and recommendations for exercise procedures. Med Sci Sports Exerc. 1997;29(3):306–12.
Wisloff U, Stoylen A, Loennechen JP, Bruvold M, Rognmo O, Haram PM, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007;115(24):3086–94.
Moholdt T, Aamot IL, Granoien I, Gjerde L, Myklebust G, Walderhaug L, et al. Long-term follow-up after cardiac rehabilitation: a randomized study of usual care exercise training versus aerobic interval training after myocardial infarction. Int J Cardiol. 2011;152(3):388–90.
Elliott AD, Rajopadhyaya K, Bentley DJ, Beltrame JF, Aromataris EC. Interval training versus continuous exercise in patients with coronary artery disease: a meta-analysis. Heart Lung Circ. 2015;24(2):149–57.
World Health Organization. Global recommendations on physical activity for health. Geneva: World Health Organization; 2010.
Kiilavuori K, Sovijärvi A, Näveri H, Ikonen T, Leinonen H. Effect of physical training on exercise capacity and gas exchange in patients with chronic heart failure. Chest. 1996;110(4):985–91.
Edelmann F, Gelbrich G, Düngen H-D, Fröhling S, Wachter R. Stahrenberg R, et al. In: Exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction results of the ex-DHF (exercise training in diastolic heart failure) pilot study; 2015.
Feiereisen P, Delagardelle C, Vaillant M, Lasar Y, Beissel J. Is strength training the more efficient training modality in chronic heart failure? Med Sci Sports Exerc. 2007;39(11):1910–7.
Marzolini S, Oh PI, Thomas SG, Goodman JM. Aerobic and resistance training in coronary disease: single versus multiple sets. Med Sci Sports Exerc. 2008;40(9):1557–64.
Levinger I, Bronks R, Cody DV, Linton I, Davie A. The effect of resistance training on left ventricular function and structure of patients with chronic heart failure. Int J Cardiol. 2005;105(2):159–63.
Fredriksen PM, Kahrs N, Blaasvaer S, Sigurdsen E, Gundersen O, Roeksund O, et al. Effect of physical training in children and adolescents with congenital heart disease. Cardiol Young. 2000;10(2):107–14.
Dua JS, Cooper AR, Fox KR, Stuart AG. Exercise training in adults with congenital heart disease: feasibility and benefits. Int J Cardiol. 2010;138(2):196–205.
Haskell WL, Lee I-M, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical activity and public health. Updated recommendation for adults from the American College of Sports Medicine and the American Heart Association Circulation. Med Sci Sports Exerc. 2007;39(8):1423–34.
Tudor-Locke C, Craig CL, Brown WJ, Clemes SA, De Cocker K, Giles-Corti B, et al. How many steps/day are enough? For adults. Int J Behav Nutr Phys Act. 2011;8:79.
Rognmo O, Moholdt T, Bakken H, Hole T, Molstad P, Myhr N, et al. Cardiovascular risk of high- versus moderate- intensity aerobic exercise in coronary heart disease patients. Circulation. 2012;126:1436–40.
Thorp AA, Owen N, Neuhaus M, Dunstan DW. Sedentary behaviors and subsequent health outcomes in adults: a systematic review of longitudinal studies, 1996–2011. Am J Prev Med. 2011;41(2):207–15.
Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA. 1995;273(5):402–7.
Therrien J, Fredriksen P, Walker M, Granton J, Reid GJ, Webb G. A pilot study of exercise training in adult patients with repaired tetralogy of Fallot. Can J Cardiol. 2003;19(6):685–9.
Duppen N, Kapusta L, de Rijke Y, Snoeren M, Kuipers I, Koopman L, et al. The effect of exercise training on cardiac remodelling in children and young adults with corrected tetralogy of Fallot or Fontan circulation: a randomized controlled trial. Int J Cardiol. 2015;179:97–104.
Westhoff-Bleck M, Schieffer B, Tegtbur U, Meyer GP, Hoy L, Schaefer A, et al. Aerobic training in adults after atrial switch procedure for transposition of the great arteries improves exercise capacity without impairing systemic right ventricular function. Int J Cardiol. 2013;170(1):24–9.
Sutherland N, Jones B, d’Udekem Y. Should we recommend exercise after the Fontan procedure? Heart Lung Circ. 2015;24(8):753–68.
Longmuir PE, Tyrrell PN, Corey M, Faulkner G, Russell JL, McCrindle BW. Home-based rehabilitation enhances daily physical activity and motor skill in children who have undergone the Fontan procedure. Pediatr Cardiol. 2013;34(5):1130–51.
Moore SM, Charvat JM, Gordon NH, Roberts BL, Pashkow F, Ribisl P, et al. Effects of a CHANGE intervention to increase exercise maintenance following cardiac events. Ann Behav Med. 2006;31(1):53–62.
Bock BC, Carmona-Barros RE, Esler JL, Tilkemeier PL. Program participation and physical activity maintenance after cardiac rehabilitation. Behav Modif. 2003;27(1):37–53.
Stone JA, Arena R, Hauer T, Martin BJ, Austford LD, Aggarwal S. Long-term retention of aerobic fitness improvements following participation in cardiac rehabilitation. Int J Cardiol. 2011;150(3):355–6.
Longmuir PE, Brothers JA, de Ferranti SD, Hayman LL, Van Hare GF, Matherne GP, et al. Promotion of physical activity for children and adults with congenital heart disease a scientific statement from the American Heart Association. Circulation. 2013;127(21):2147–59.
Sandberg C, Pomeroy J, Thilén U, Gradmark A, Wadell K, Johansson B. Habitual physical activity in adults with congenital heart disease compared to age and gender matched controls. Can J Cardiol. 2016;32(4):547–53.
Müller J, Hess J, Hager A. Daily physical activity in adults with congenital heart disease is positively correlated with exercise capacity but not with quality of life. Clin Res Cardiol. 2012;101(1):55–61.
Tudor-Locke C, Bassett DR Jr. How many steps/day are enough? Preliminary pedometer indices for public health. Sports Med. 2004;34(1):1–8.
Dua JS, Cooper AR, Fox KR. Physical activity levels in adults with congenital heart disease. Eur J Cardiovasc Prev Rehabil. 2007;14(2):287–93.
Dontje ML, van der Wal MH, Stolk RP, Brugemann J, Jaarsma T, Wijtvliet PE, et al. Daily physical activity in stable heart failure patients. J Cardiovasc Nurs. 2014;29(3):218–26.
Buys R, Budts W, Delecluse C, Vanhees L. Determinants of physical activity in young adults with tetralogy of Fallot. Cardiol Young. 2014;24(1):20–6.
Lawler PR, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation post-myocardial infarction: a systematic review and meta-analysis of randomized controlled trials. Am Heart J. 2011;162(4):571–84.e2.
Bassareo P, Saba L, Solla P, Barbanti C, Marras A, Mercuro G. Factors influencing adaptation and performance at physical exercise in complex congenital heart diseases after surgical repair. Biomed Res Int. 2014;2014:1.
Healy GN, Dunstan DW, Salmon J, Cerin E, Shaw JE, Zimmet PZ, et al. Breaks in sedentary time: beneficial associations with metabolic risk. Diabetes Care. 2008;31(4):661–6.
Tremblay MS, Warburton DE, Janssen I, Paterson DH, Latimer AE, Rhodes RE, et al. New Canadian physical activity guidelines. Appl Physiol Nutr Metab. 2011;36(1):36–46, 47–58.
Owen N, Healy GN, Matthews CE, Dunstan DW. Too much sitting: the population health science of sedentary behavior. Exerc Sport Sci Rev. 2010;38(3):105–13.
Manns PJ, Dunstan DW, Owen N, Healy GN. Addressing the nonexercise part of the activity continuum: a more realistic and achievable approach to activity programming for adults with mobility disability? Phys Ther. 2012;92(4):614–25.
Jakicic JM, Rickman AD, Lang W, Davis KK, Gibbs BB, Neiberg R, et al. Time-based physical activity interventions for weight loss: a randomized trial. Med Sci Sports Exerc. 2015;47(5):1061.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Willner, J., Haennel, R., Ramadi, A., Muhll, I.V., Mackie, A. (2019). Cardiac Rehabilitation in Adults with Congenital Heart Disease. In: da Cruz, E., Macrae, D., Webb, G. (eds) Intensive Care of the Adult with Congenital Heart Disease. Congenital Heart Disease in Adolescents and Adults. Springer, Cham. https://doi.org/10.1007/978-3-319-94171-4_25
Download citation
DOI: https://doi.org/10.1007/978-3-319-94171-4_25
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-94170-7
Online ISBN: 978-3-319-94171-4
eBook Packages: MedicineMedicine (R0)