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Animal Biotechnology 2 pp 1–20Cite as

Cloning of Livestock by Somatic Cell Nuclear Transfer

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Abstract

Since the cloning of “Dolly” by somatic cell nuclear transfer in 1996, numerous articles have been published concerning the application of this technology to a large variety of mammalian species including all the major livestock species. While live births have been obtained for many species, the efficiency of cellular reprogramming essential for success has not been significantly improved. This chapter will attempt to address the inputs utilized for this procedure and the major manipulation steps with the objective of identifying the major factors which might affect this efficiency of reprogramming and some of the studies addressing these factors. Finally, the challenging task of setting optimum endpoints for experiments involving domestic species will be discussed.

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Authors and Affiliations

  1. School of Animal Sciences, Louisiana State University, Agricultural Center, Baton Rouge, LA, 70803, USA

    Kenneth R. Bondioli

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  1. Kenneth R. Bondioli
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Correspondence to Kenneth R. Bondioli .

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Editors and Affiliations

  1. Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut (FLI), Mariensee, Germany

    Heiner Niemann

  2. Faculty of Veterinary Medicine, Justus-Liebig-University Giessen, Giessen, Germany

    Christine Wrenzycki

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Bondioli, K.R. (2018). Cloning of Livestock by Somatic Cell Nuclear Transfer. In: Niemann, H., Wrenzycki, C. (eds) Animal Biotechnology 2. Springer, Cham. https://doi.org/10.1007/978-3-319-92348-2_1

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