Concomitant Diseases of Mammary Glands and Other Organs

Abstract

Breast diseases are combined with the pathology of other organs in 77% of cases. The primary multiplicity of tumors is now defined as the independent occurrence and development of two or more neoplasms in the body of one patient. In this case, not only different organs of different systems but also paired organs (mammary glands, lungs, etc.) can be affected. Multicentric lesions of one organ can occur as well. Combination of two tumors predominates in the structure of polyneoplasias. The cases of triple localization occur in 5–8% of cases. The risk of developing tumors in patients already having neoplasms is approximately 1.3 times higher than in those who did not previously have neoplasms. The risk of breast cancer depends on the intensity of the proliferation of the lobular and/or ductal epithelium and increases by 3–5 times at preexisting benign breast diseases, especially in combination with diseases of reproductive organs. Metastatic lesions in mammary glands can occur in cases of primary tumors of various localizations. These cases are rare and are often associated with poor prognosis.