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Infections of the Ears, Nose, Throat, and Sinuses pp 67–78Cite as

Mastoiditis

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Abstract

Mastoiditis encompasses a spectrum of infectious processes within the mastoid air cells that may develop as a complication of otitis media. Acute or chronic mastoiditis may result in the destruction of the bony septae and cortex of the mastoid as well as the extension of the infection into adjacent structures. Potential complications of mastoiditis include soft tissue abscess, petrositis, facial paralysis, labyrinthitis, meningitis, sinus thrombosis, and brain abscess. Fortunately, the incidence of mastoiditis and its complications has decreased over the past 75 years since the introduction of antibiotics. This chapter reviews the epidemiology, microbiology, diagnosis, complications, and treatment of mastoiditis.

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References>

  1. Pichichero ME, Media O. Pediatr Clin North Am. 2013;60:391–407.

    Article  PubMed  Google Scholar 

  2. Van Zuijlen D, Schilder A, Van Balen F, Hoes A. No TitleNational differences in incidence of acute mastoiditis: relationship to prescribing patterns of antibiotics for acute otitis media? Pediatr Infect Dis J. 2001;20:140–4.

    Article  PubMed  Google Scholar 

  3. Pritchett CV, Thorne MC. Incidence of pediatric acute mastoiditis: 1997-2006. Arch Otolaryngol Head Neck Surg. 2012;138:451–5.

    Article  PubMed  Google Scholar 

  4. Nunez DA. Risks of developing an otogenic intracranial abscess. J Laryngol Otol. 1990;104:468–72.

    Article  CAS  PubMed  Google Scholar 

  5. Browning G, Gatehouse S. The prevalence of middle ear disease in the adult British poulation. Clin Otolaryngol Allied Sci. 1992;17:317–21.

    Article  CAS  PubMed  Google Scholar 

  6. Palma S, Bovo R, Benatti A, Aimoni C, Rosignoli M, Libanore M, et al. Mastoiditis in adults: a 19-year retrospective study. Eur Arch Otorhinolaryngol. 2014;271(5):925–31.

    Article  CAS  PubMed  Google Scholar 

  7. Whitney C, Farley M, Hadler J, Harrison L. Decline in invasive pneumococcal disease after the introduction of protein–polysaccharide conjugate vaccine. N Engl J Med. 2003;348:1737–46.

    Article  PubMed  Google Scholar 

  8. Kaplan SL, Mason EOJ, Wald ER, Schutze GE, Bradley JS, Tan TQ, et al. Decrease of invasive pneumococcal infections in children among 8 children’s hospitals in the United States after the introduction of the 7-valent pneumococcal conjugate vaccine. Pediatrics. 2004;113(3 Pt 1):443–9.

    Article  PubMed  Google Scholar 

  9. Kangsanarak J, Fooanant S, Ruckphaopunt K, Navacharoen N, Teotrakul S. Extracranial and intracranial complications of suppurative otitis media. Report of 102 cases. J Laryngol Otol. 1993;107:999–1004.

    Article  CAS  PubMed  Google Scholar 

  10. Froom J, Culpepper L, Green LA, de Melker RA, Grob P, Heeren T, et al. A cross-national study of acute otitis media: risk factors, severity, and treatment at initial visit. Report from the International Primary Care Network (IPCN) and the Ambulatory Sentinel Practice Network (ASPN). J Am Board Fam Pract. 2001;14:406–17.

    PubMed  CAS  Google Scholar 

  11. Spiegel JH, Lustig LR, Lee KC, Murr AH, Schindler RA. Contemporary presentation and management of a spectrum of mastoid abscesses. Laryngoscope. 1998;108:822–8.

    Article  PubMed  CAS  Google Scholar 

  12. Hoshino T, Takeuchi N, Fukasawa C, Hirose S, Okui H, Sato H, et al. Analysis of Streptococcus pneumoniae and Haemophilus influenzae isolated from middle ear fluid before and after the introduction of government subsidies for pneumococcal and H. influenzae type b vaccines in Japan. J Infect Chemother. 2017;23:85–9.

    Article  PubMed  Google Scholar 

  13. Dagan R, Pelton S, Bakaletz L, Cohen R. Prevention of early episodes of otitis media by pneumococcal vaccines might reduce progression to complex disease. Lancet Infect Dis. 2016;16(4):480–92.

    Article  PubMed  Google Scholar 

  14. Tawfik KO, Ishman SL, Altaye M, Meinzen-Derr J, Choo DI. Pediatric acute otitis media in the era of pneumococcal vaccination. Otolaryngol Head Neck Surg. 2017;156:938–45.

    Article  PubMed  Google Scholar 

  15. Choi SS, Lander L. Pediatric acute mastoiditis in the post-pneumococcal conjugate vaccine era. Laryngoscope. 2011;121:1072–80.

    Article  PubMed  Google Scholar 

  16. Kaplan SL, Center KJ, Barson WJ, et al. Multicenter surveillance of Streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate vaccine era. Clin Infect Dis. 2015;60:1339–45.

    Article  PubMed  Google Scholar 

  17. Koutouzis EI, Koutouzi FI, Chatzichristou P, et al. Pneumococcal mastoiditis in children before and after the introduction of conjugate pneumococcal vaccines. Pediatr Infect Dis. 2016;35:292–6.

    Article  Google Scholar 

  18. Ongkasuwan J, T a V, Hulten KG, Mason EO, Kaplan SL. Pneumococcal mastoiditis in children and the emergence of multidrug-resistant serotype 19A isolates. Pediatrics. 2008;122:34–9.

    Article  PubMed  Google Scholar 

  19. Luntz M, Brodsky A, Nusem S, Kronenberg J, Keren G, Migirov L, et al. Acute mastoiditis - the antibiotic era: a multicenter study. Int J Pediatr Otorhinolaryngol. 2001;57:1–9.

    Article  PubMed  CAS  Google Scholar 

  20. Pelton SI, Huot H, Finkelstein JA, Bishop CJ, Hsu KK, Kellenberg J, et al. Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2007;26:468–72.

    Article  PubMed  Google Scholar 

  21. Messina AF, Katz-Gaynor K, Barton T, Ahmad N, Ghaffar F, Rasko D, et al. Impact of the pneumococcal conjugate vaccine on serotype distribution and antimicrobial resistance of invasive Streptococcus pneumoniae isolates in Dallas, TX, children from 1999 through 2005. Pediatr Infect Dis J. 2007;26:461–7.

    Article  PubMed  Google Scholar 

  22. Pichichero ME, Casey JR. Emergence of a multiresistant serotype 19A pneumococcal strain not included in the 7-valent conjugate vaccine as an otopathogen in children. JAMA. 2007;298:1772–8.

    Article  PubMed  CAS  Google Scholar 

  23. Hicks LA, Harrison LH, Flannery B, Hadler JL, Schaffner W, Craig AS, et al. Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination for the Active Bacterial Core Surveillance Program of the Emerging Infections Program Network. J Infect Dis. 2007;196:1346–54.

    Article  PubMed  Google Scholar 

  24. Bakhos D, Trijolet J-P, Morinière S, Pondaven S, Al zahrani M, Lescanne E. Conservative management of acute mastoiditis in children. Arch Otolaryngol Neck Surg. 2011;137:346.

    Article  Google Scholar 

  25. Chole RA, Sudhoff HH. Chronic otitis media, mastoiditis, and petrositis. In:Cummings otolaryngology: head & neck surgery. 5th ed. Philadelphia, PA: Mosby, Inc.; 2010.

    Google Scholar 

  26. Zevallos JP, Vrabec JT, Williamson RA, Giannoni C, Larrier D, Sulek M, et al. Advanced pediatric mastoiditis with and without intracranial complications. Laryngoscope. 2009;119:1610–5.

    Article  PubMed  Google Scholar 

  27. Williams JR. Masked mastoditis. NY State N Med. 1966;66:1102–7.

    CAS  Google Scholar 

  28. Holt G, Gates G. Masked mastoiditis. Laryngoscope. 1983;93:1034–7.

    Article  PubMed  CAS  Google Scholar 

  29. Voudouris C, Psarommatis I, Nikas I, Kafouris D, Chrysouli K. Pediatric masked mastoiditis associated with multiple intracranial complications. Case Rep Otolaryngol. 2015;2015:1–4.

    Article  Google Scholar 

  30. Dawes J. Complications of infection of the middle ear. In: Ballantyne K, Grove J, editors. Scott-Brown’s disease of the ear, nose, and throat. 4th ed; 1979. p. 305–84.

    Google Scholar 

  31. Taylor MF, Berkowitz RG. Indications for mastoidectomy in acute mastoiditis in children. Ann Otol Rhinol Laryngol. 2004;113:69–72.

    Article  PubMed  Google Scholar 

  32. Bauer PW, Brown KR, Jones DT. Mastoid subperiosteal abscess management in children. Int J Pediatr Otorhinolaryngol. 2002;63:185–8.

    Article  PubMed  Google Scholar 

  33. Marioni G, de Filippis C, Tregnaghi A, Marchese-Ragona R, Staffieri A. Bezold’s abscess in children: case report and review of the literature. Int J Pediatr Otorhinolaryngol. 2001;61:173–7.

    Article  CAS  PubMed  Google Scholar 

  34. Gadre AK, Chole RA. The changing face of petrous apicitis-a 40-year experience. Laryngoscope. 2018;128:195–201. Available from: http://doi.wiley.com/10.1002/lary.26571.

    Article  PubMed  Google Scholar 

  35. Isaacson B. Cholesterol granuloma and other petrous apex lesions. Otolaryngol Clin North Am. 2015;48(2):361–73.

    Article  PubMed  Google Scholar 

  36. Schuknecht H. Pathology of the ear. Philadelphia, PA: Lea and Febiger; 1993.

    Google Scholar 

  37. Maranhao AS d A, Godofredo VR, Penido N d O. Suppurative labyrinthitis associated with otitis media: 26 years’ experience. Braz J Otorhinolaryngol. 2016;82:82–7.

    Article  PubMed  Google Scholar 

  38. Nomiya S, Kariya S, Nomiya R, Morita N, Nishizaki K, Paparella MM, et al. Facial nerve canal dehiscence in chronic otitis media without cholesteatoma. Eur Arch Oto Rhino Laryngol. 2014;271:455–8.

    Article  Google Scholar 

  39. Makeham TP, Croxson GR, Coulson S. Infective causes of facial nerve paralysis. Otol Neurotol. 2007;28:100–3.

    Article  PubMed  Google Scholar 

  40. Go C, Bernstein JM, De Jong AL, Sulek M, Friedman EM. Intracranial complications of acute mastoiditis. Int J Pediatr Otorhinolaryngol. 2000;52:143–8.

    Article  PubMed  CAS  Google Scholar 

  41. Leskinen K, Jero J. Acute complications of otitis media in adults. Clin Otolaryngol. 2005;30(6):511.

    Article  PubMed  CAS  Google Scholar 

  42. Penido NO, Borin A, Iha LCN, Suguri VM, Onishi E, Fukuda Y, et al. Intracranial complications of otitis media: 15 years of experience in 33 patients. Otolaryngol Head Neck Surg. 2005;132:37–42.

    Article  Google Scholar 

  43. van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med. 2004;351:1849–59.

    Article  PubMed  Google Scholar 

  44. Dubey SP, Larawin V, Molumi CP. Intracranial spread of chronic middle ear suppuration. Am J Otolaryngol Head Neck Med Surg. 2010;31:73–7.

    Google Scholar 

  45. Slattery H, House J. Complications of otitis media. In: Lalwani A, Grundfast K, editors. Pediatric otology and neurotology. New York, NY: Lippincott-Raven; 1998.

    Google Scholar 

  46. Brouwer MC, Heckenberg SGB, de Gans J, Spanjaard L, Reitsma JB, van de Beek D. Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology. 2010;75:1533–9.

    Article  PubMed  CAS  Google Scholar 

  47. Rajasingham CR, Bonsu BK, Chapman JI, Cohen DM, Barson WJ. Serious neurologic sequelae in cases of meningitis arising from infection by conjugate vaccine-related and nonvaccine-related serogroups of Streptococcus pneumoniae. Pediatr Infect Dis J. 2008;27:771–5.

    Article  PubMed  Google Scholar 

  48. Watt JP, Levine OS, Santosham M. Global reduction of Hib disease: what are the next steps? Proceedings of the meeting Scottsdale, Arizona, September 22–25, 2002. J Pediatr. 2003;143(6 Suppl):S163–87.

    Article  PubMed  Google Scholar 

  49. Olarte L, Barson WJ, Barson RM, et al. Impact of the 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in US children. Clin Infect Dis. 2015;61(5):767–75.

    Article  PubMed  Google Scholar 

  50. Greenberg JS, Manolidis S. High incidence of complications encountered in chronic otitis media surgery in a U.S. metropolitan public hospital. Otolaryngol Head Neck Surg. 2001;125:623–7.

    Article  PubMed  CAS  Google Scholar 

  51. Sennaroglu L, Sozeri B. Otogenic brain abscess: review of 41 cases. Otolaryngol Head Neck Surg. 2000;123:751–5.

    Article  PubMed  CAS  Google Scholar 

  52. Szyfter W, Kruk-Zagajewska A, Borucki Ł, Bartochowska A. Evolution in management of otogenic brain abscess. Otol Neurotol. 2012;33:393–5.

    Article  PubMed  Google Scholar 

  53. Hafidh MA, Keogh I, Walsh RMC, Walsh M, Rawluk D. Otogenic intracranial complications. A 7-year retrospective review. Am J Otolaryngol Head Neck Med Surg. 2006;27:390–5.

    Google Scholar 

  54. Tandon S, Beasley N, Swift a C. Changing trends in intracranial abscesses secondary to ear and sinus disease. J Laryngol Otol. 2009;123:283–8.

    Article  PubMed  CAS  Google Scholar 

  55. Singh B, Maharaj T. Radical mastoidectomy: its place in otitic intracranial complications. J Laryngol Otol. 1993;107:1113–8.

    PubMed  CAS  Google Scholar 

  56. Levy R, Shvero J, Hadar T. Stapedotomy technique and results: ten years’ experience and comparative study with stapedectomy. Laryngoscope. 1990;100:1097–9.

    Article  PubMed  CAS  Google Scholar 

  57. Wackym PA, Canalis RF, Feuerman T. Subdural empyema of otorhinological origin. J Laryngol Otol. 1990;104:118–22.

    Article  PubMed  CAS  Google Scholar 

  58. Bales CB, Sobol S, Wetmore R, Elden LM. Lateral sinus thrombosis as a complication of otitis media: 10-year experience at the children’s hospital of Philadelphia. Pediatrics. 2009;123:709–13.

    Article  PubMed  Google Scholar 

  59. Manolidis S, Kutz JW. Diagnosis and management of lateral sinus thrombosis. Otol Neurotol. 2005;26:1045–51.

    Article  PubMed  Google Scholar 

  60. Agarwal A, Lowry P, Isaacson G. Natural history of sigmoid sinus thrombosis. Ann Otol Rhinol Laryngol. 2003;112:191–4.

    Article  PubMed  Google Scholar 

  61. Neilan RE, Isaacson B, Kutz JW, Lee KH, Roland PS. Pediatric otogenic lateral sinus thrombosis recanalization. Int J Pediatr Otorhinolaryngol. 2011;75:850–3.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Otolaryngology-Head & Neck Surgery, Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA

    Kenny Lin & Lawrence R. Lustig

  2. Department of Radiology, Columbia University Medical Center, New York, NY, USA

    Gul Moonis

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  1. Kenny Lin
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  2. Gul Moonis
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  3. Lawrence R. Lustig
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Correspondence to Lawrence R. Lustig .

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Editors and Affiliations

  1. Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

    Marlene L. Durand

  2. Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA

    Daniel G. Deschler

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Lin, K., Moonis, G., Lustig, L.R. (2018). Mastoiditis. In: Durand, M., Deschler, D. (eds) Infections of the Ears, Nose, Throat, and Sinuses. Springer, Cham. https://doi.org/10.1007/978-3-319-74835-1_6

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  • DOI: https://doi.org/10.1007/978-3-319-74835-1_6

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