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Hot Topics in TAVI: Paravalvular Leak, Thrombosis, PM Implantation, Stroke, Durability

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Advances in Treatments for Aortic Valve and Root Diseases

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Abstract

Transcatheter aortic valve implantation (TAVI) is a rapidly evolving technique providing robust treatment of severe aortic valve stenosis, at least in high and intermediate risk patient cohorts [1]. However, different important limitations, having a potential impact on patient outcome, still need to be resolved. Indeed, with several first-generation balloon-expandable or self-expanding TAVI prostheses, residual paravalvular aortic regurgitation (PVL) after TAVI has been identified as a significant independent major predictor of acute and long-term mortality. Moreover, conduction disorders requiring pacemaker implantation and also concerns about early (leaflet thrombosis/decreased leaflet motion) and late valve durability, need to be resolved before applying TAVI to lower-risk patient cohorts [2].

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Authors and Affiliations

  1. Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), IRCSS UPMC ITALY, Palermo, PA, 90127, Italy

    Caterina Gandolfo

  2. Maria Eleonora Hospital, GVM, Palermo, Italy

    Amerigo Stabile Ph.D.

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  1. Caterina Gandolfo
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  2. Amerigo Stabile Ph.D.
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Correspondence to Caterina Gandolfo .

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Editors and Affiliations

  1. Department of Cardiothoracic and Vascular Surgery, GVM Care and Research, MEH, University of Palermo, Palermo, Italy

    Khalil Fattouch

  2. Department of Cardiology, University of Liège, Liège, Belgium

    Patrizio Lancellotti

  3. Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA

    Mani A. Vannan

  4. Cardiovascular Surgery Department, GVM Care & Research, Anthea Hospital, Bari, Italy

    Giuseppe Speziale

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Gandolfo, C., Stabile, A. (2018). Hot Topics in TAVI: Paravalvular Leak, Thrombosis, PM Implantation, Stroke, Durability. In: Fattouch, K., Lancellotti, P., Vannan, M., Speziale, G. (eds) Advances in Treatments for Aortic Valve and Root Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-66483-5_24

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