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Oncoplastic and Reconstructive Breast Surgery pp 651–660Cite as

Fat Grafting in Breast Reconstruction

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Abstract

Lipofilling is an autologous technique used in breast reconstruction. It is also known as “fat transfer,” “lipotransfer,” “fat injection,” or “fat transplantation,” as well as many other terminologies. The procedure consists of two major steps which are liposuction and lipoinjection of the patient’s own fat tissue and other tissue elements, either with or without specific preparation processes before lipoinjection. It is considered as a minimally invasive procedure which can be effectively performed under local or general anesthesia.

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References

  1. Vallejo A, Urban C, Zucca-Matthes G, Rietjens M (2013) Is there enough evidence to use lipofilling in breast cancer reconstruction? Plast Reconstr Surg 132(4):447–454

    Article  Google Scholar 

  2. Coleman SR (2002) Hand rejuvenation with structural fat grafting. Plast Reconstr Surg 110(7):1731–1744 discussion 45–47

    Article  Google Scholar 

  3. Coleman SR (2006) Facial augmentation with structural fat grafting. Clin Plast Surg 33(4):567–577

    Article  Google Scholar 

  4. von Heimburg D, Pallua N (2001) Two-year histological outcome of facial lipofilling. Ann Plast Surg 46(6):644–646

    Article  Google Scholar 

  5. Andre P (2002) Facial lipoatrophy secondary to a new synthetic filler device (Profill) treated by lipofilling. J Cosmet Dermatol 1(2):59–61

    Article  Google Scholar 

  6. Bertossi D, Zancanaro C, Trevisiol L, Albanese M, Ferrari F, Nocini PF (2003) Lipofilling of the lips: ultrastructural evaluation by transmission electron microscopy of injected adipose tissue. Arch Facial Plast Surg 5(5):392–398

    Article  Google Scholar 

  7. Gutowski KA (2009) Current applications and safety of autologous fat grafts: a report of the ASPS fat graft task force. Plast Reconstr Surg 124(1):272–280

    Article  CAS  Google Scholar 

  8. Petit JY, Clough K, Sarfati I, Lohsiriwat V, de Lorenzi F, Rietjens M (2010) Lipofilling in breast cancer patients: from surgical technique to oncologic point of view. Plast Reconstr Surg 126(5):262e–263e

    Article  Google Scholar 

  9. Petit JY, Botteri E, Lohsiriwat V, Rietjens M, De Lorenzi F, Garusi C et al (2012) Locoregional recurrence risk after lipofilling in breast cancer patients. Ann Oncol 23(3):582–588

    Article  CAS  Google Scholar 

  10. Lohsiriwat V, Curigliano G, Rietjens M, Goldhirsch A, Petit JY (2011) Autologous fat transplantation in patients with breast cancer: “silencing” or “fueling” cancer recurrence? Breast 20(4):351–357

    Article  Google Scholar 

  11. Petit JY, Lohsiriwat V, Clough KB, Sarfati I, Ihrai T, Rietjens M et al (2011) The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study-milan-paris-lyon experience of 646 lipofilling procedures. Plast Reconstr Surg 128(2):341–346

    Article  CAS  Google Scholar 

  12. Rietjens M, De Lorenzi F, Rossetto F, Brenelli F, Manconi A, Martella S et al (2011) Safety of fat grafting in secondary breast reconstruction after cancer. J Plast Reconstr Aesthet Surg 64(4):477–483

    Article  CAS  Google Scholar 

  13. Eto H, Suga H, Matsumoto D, Inoue K, Aoi N, Kato H et al (2009) Characterization of structure and cellular components of aspirated and excised adipose tissue. Plast Reconstr Surg 124(4):1087–1097

    Article  CAS  Google Scholar 

  14. Suga H, Matsumoto D, Inoue K, Shigeura T, Eto H, Aoi N et al (2008) Numerical measurement of viable and nonviable adipocytes and other cellular components in aspirated fat tissue. Plast Reconstr Surg 122(1):103–114

    Article  CAS  Google Scholar 

  15. Coleman SR (1995) Long-term survival of fat transplants: controlled demonstrations. Aesthet Plast Surg 19(5):421–425

    Article  CAS  Google Scholar 

  16. Sommer B, Sattler G (2000) Current concepts of fat graft survival: histology of aspirated adipose tissue and review of the literature. Dermatol Surg 26(12):1159–1166

    Article  CAS  Google Scholar 

  17. Kaufman MR, Miller TA, Huang C, Roostaeian J, Wasson KL, Ashley RK et al (2007) Autologous fat transfer for facial recontouring: is there science behind the art? Plast Reconstr Surg 119(7):2287–2296

    Article  CAS  Google Scholar 

  18. Gonzalez AM, Lobocki C, Kelly CP, Jackson IT (2007) An alternative method for harvest and processing fat grafts: an in vitro study of cell viability and survival. Plast Reconstr Surg 120(1):285–294

    Article  CAS  Google Scholar 

  19. Erdim M, Tezel E, Numanoglu A, Sav A (2009) The effects of the size of liposuction cannula on adipocyte survival and the optimum temperature for fat graft storage: an experimental study. J Plast Reconstr Aesthet Surg 62(9):1210–1214

    Article  Google Scholar 

  20. Sasaki GH (2011) Water-assisted liposuction for body contouring and lipoharvesting: safety and efficacy in 41 consecutive patients. Aesthet Surg J 31(1):76–88

    Article  Google Scholar 

  21. Fraser JK, Zhu M, Wulur I, Alfonso Z (2008) Adipose-derived stem cells. Methods Mol Biol 449:59–67

    PubMed  Google Scholar 

  22. Karacalar A, Orak I, Kaplan S, Yildirim S (2004) No-touch technique for autologous fat harvesting. Aesthet Plast Surg 28(3):158–164

    Article  Google Scholar 

  23. Pulsfort AK, Wolter TP, Pallua N (2011) The effect of centrifugal forces on viability of adipocytes in centrifuged lipoaspirates. Ann Plast Surg 66(3):292–295

    Article  CAS  Google Scholar 

  24. Kim IH, Yang JD, Lee DG, Chung HY, Cho BC (2009) Evaluation of centrifugation technique and effect of epinephrine on fat cell viability in autologous fat injection. Aesthet Surg J 29(1):35–39

    Article  Google Scholar 

  25. Conde-Green A, Baptista LS, de Amorin NF, de Oliveira ED, da Silva KR, Pedrosa Cda S et al (2010) Effects of centrifugation on cell composition and viability of aspirated adipose tissue processed for transplantation. Aesthet Surg J 30(2):249–255

    Article  Google Scholar 

  26. Hong SJ, Lee JH, Hong SM, Park CH (2010) Enhancing the viability of fat grafts using new transfer medium containing insulin and beta-fibroblast growth factor in autologous fat transplantation. J Plast Reconstr Aesthet Surg 63(7):1202–1208

    Article  Google Scholar 

  27. Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K (2008) Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells. Aesthet Plast Surg 32(1):48–55 discussion 6–7

    Article  Google Scholar 

  28. Matsumoto D, Sato K, Gonda K, Takaki Y, Shigeura T, Sato T et al (2006) Cell-assisted lipotransfer: supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection. Tissue Eng 12(12):3375–3382

    Article  CAS  Google Scholar 

  29. Babovic S (2010) Complete breast reconstruction with autologous fat graft—a case report. J Plast Reconstr Aesthet Surg 63(7):e561–e563

    Article  Google Scholar 

  30. Biazus JV, Falcão CC, Parizotto AC, Stumpf CC, Cavalheiro JAC, Schuh F, Cericatto R, Zucatto ÂE, Melo MP (2015) Immediate reconstruction with autologous fat transfer following breast-conserving surgery. Breast J 21:268–275. https://doi.org/10.1111/tbj.12397

    Article  PubMed  Google Scholar 

  31. Alexander Del Vecchio D, Bucky LP (2011) Breast augmentation using pre-expansion and autologous fat transplantation—a clinical radiological study. Plast Reconstr Surg 127:2441–2450

    Article  Google Scholar 

  32. Del Vecchio D (2009) Breast reconstruction for breast asymmetry using recipient site pre-expansion and autologous fat grafting: a case report. Ann Plast Surg 62(5):523–527

    Article  Google Scholar 

  33. Khouri R, Del Vecchio D (2009) Breast reconstruction and augmentation using pre-expansion and autologous fat transplantation. Clin Plast Surg 36(2):269–280 viii

    Article  Google Scholar 

  34. Hamdi M, Andrades P, Thiessen F, Stillaert F, Roche N, Van Landuyt K et al (2010) Is a second free flap still an option in a failed free flap breast reconstruction? Plast Reconstr Surg 126(2):375–384

    Article  CAS  Google Scholar 

  35. Zocchi ML, Zuliani F (2008) Bicompartmental breast lipostructuring. Aesthet Plast Surg 32(2):313–328

    Article  CAS  Google Scholar 

  36. Brenelli F, Rietjens M, De Lorenzi F, Pinto-Neto A, Rossetto F, Martella S, Rodrigues JRP, Barbalho D (2014) Oncological safety of autologous fat grafting after breast conservative treatment: a prospective evaluation. Breast J 20:159–165. https://doi.org/10.1111/tbj.12225

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Division of Plastic and Reconstructive Surgery, European Instituteof Oncology, Milan, Lombardia, Italy

    Mario Rietjens

  2. Plastic and Reconstructive Department, European Institute of Oncology—IEO, Milan, Italy

    Visnu Lohsiriwat

  3. Department of Surgery, Siriraj Hospital, Mahidol University Medical School, Bangkok, Thailand

    Cicero Urban

  4. Breast Unit, Our Lady of Grace Hospital and Positivo University Medical School, Curitiba, Brazil

    Andrea Manconi

Authors
  1. Mario Rietjens
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  2. Visnu Lohsiriwat
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  3. Cicero Urban
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  4. Andrea Manconi
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Corresponding author

Correspondence to Mario Rietjens .

Editor information

Editors and Affiliations

  1. Our Lady of Grace Hospital, Positivo University, Curitiba, Brazil

    Cicero Urban

  2. Plastic and Reconstructive Division, European Institute of Oncology, Milan, Italy

    Mario Rietjens

  3. Memorial Sloan Kettering Cancer Center, New York, USA

    Mahmoud El-Tamer

  4. Memorial Sloan Kettering Cancer Center, New York, USA

    Virgilio S. Sacchini

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Rietjens, M., Lohsiriwat, V., Urban, C., Manconi, A. (2019). Fat Grafting in Breast Reconstruction. In: Urban, C., Rietjens, M., El-Tamer, M., Sacchini, V.S. (eds) Oncoplastic and Reconstructive Breast Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-62927-8_54

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  • DOI: https://doi.org/10.1007/978-3-319-62927-8_54

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62925-4

  • Online ISBN: 978-3-319-62927-8

  • eBook Packages: MedicineMedicine (R0)

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