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Essential Thrombocythemia

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Consults in Obstetric Anesthesiology

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Abstract

Essential thrombocythemia (ET) is an acquired, Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) that is characterized by a sustained elevation in platelet count (greater than 450 G/l on two occasions). Parturients with ET are at risk of hemorrhagic and, more commonly, thromboembolic events. If anticoagulated, the timing of neuraxial block will need to occur within a safe window. Early delivery planning with a multidisciplinary care team is, therefore, prudent and may prevent the need for an alternative to neuraxial analgesia/anesthesia.

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References

  1. Valera M-C, Parant O, Vayssiere C, Arnal J-F, Payrastre B. Essential thrombocythemia and pregnancy. Eur J Obstet Gynecol Reprod Biol. 2011;158(2):141–7.

    Article  Google Scholar 

  2. Chow EY, Haley LP, Vickars LM. Essential thrombocythemia in pregnancy: platelet count and pregnancy outcome. Am J Hematol. 1992;41(4):249–51.

    Article  CAS  Google Scholar 

  3. Villani M, Colaizzo D, Tiscia GL, Chinni E, Bodenizza C, Cascavilla N, et al. Postpartum haemorrhage in a woman with essential thrombocythemia carrying calreticulin mutation. Blood Coagul Fibrinolysis. 2016;27(6):727–8.

    Article  Google Scholar 

  4. Randi ML, Bertozzi I, Rumi E, Elena C, Finazzi G, Vianelli N, et al. Pregnancy complications predict thrombotic events in young women with essential thrombocythemia. Am J Hematol. 2014;89(3):306–9.

    Article  Google Scholar 

  5. Harrison C. Pregnancy and its management in the Philadelphia negative myeloproliferative diseases. Br J Haematol. 2005;129(3):293–306.

    Article  CAS  Google Scholar 

  6. Onisai M, Voican I, Ciorascu M, Popov V, Bumbea H, Gaman M, et al. Early severe preeclampsia with marked platelet dysfunction in association with essential thrombocytemia. Blood Coagul Fibrinolysis. 2015;26(7):830–7.

    Article  Google Scholar 

  7. Alimam S, Bewley S, Chappell LC, Knight M, Seed P, Gray G, et al. Pregnancy outcomes in myeloproliferative neoplasms: UK prospective cohort study. Br J Haematol. 2016;175(1):31–6.

    Article  Google Scholar 

  8. Griesshammer M, Struve S, Barbui T. Management of Philadelphia negative chronic myeloproliferative disorders in pregnancy. Blood Rev. 2008;22:235–45.

    Article  Google Scholar 

  9. Finazzi G. How to manage essential thrombocythemia. Leukemia. 2011;26:875–82.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, New York Presbyterian Weill Cornell Medicine, New York, NY, USA

    Jaime Aaronson M.D.

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  1. Jaime Aaronson M.D.
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Correspondence to Jaime Aaronson M.D. .

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Editors and Affiliations

  1. Associate Professor, Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA

    Suzanne K. W. Mankowitz

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Aaronson, J. (2018). Essential Thrombocythemia. In: Mankowitz, S. (eds) Consults in Obstetric Anesthesiology. Springer, Cham. https://doi.org/10.1007/978-3-319-59680-8_53

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  • DOI: https://doi.org/10.1007/978-3-319-59680-8_53

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59679-2

  • Online ISBN: 978-3-319-59680-8

  • eBook Packages: MedicineMedicine (R0)

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