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Osteoarthritis

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Regenerative Strategies for the Treatment of Knee Joint Disabilities

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials ((SMTEB,volume 21))

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Abstract

Osteoarthritis (OA) is the most common form of arthritis and the most relevant musculoskeletal disorder worldwide. It is considered to be a joint degenerative disease with imbalanced homeostasis. It can potentially affect any joint in the body, but most often the knees, hip, hand and the lower back suffers from OA. Due to the strong functional association of the joint components OA affects all tissues, present in the joint to a certain degree. Because of its wide occurrence, and great impact on the society OA receives a lot of attention in clinical research, although the molecular background of OA remains incompletely understood. The complexity of the joint structure, and the limited knowledge we have on OA sets many obstacles to the development of effective therapies. As of current state there is no cure for OA.

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Authors and Affiliations

  1. 3B’s Research Group—Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, AvePark, Guimarães, Portugal

    Marta Ondrésik, Joaquim Miguel Oliveira & Rui Luís Reis

  2. ICVS/3B’s—PT Government Associate Laboratory, Braga, Guimarães, Portugal

    Marta Ondrésik, Joaquim Miguel Oliveira & Rui Luís Reis

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  1. Marta Ondrésik
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  2. Joaquim Miguel Oliveira
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  1. 3B’s Research Group—Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães, Portugal

    Joaquim Miguel Oliveira

  2. ICVS/3B’s—PT Government Associate, Laboratory, University of Minho, Guimarães, Portugal

    Rui Luís Reis

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Ondrésik, M., Oliveira, J.M., Reis, R.L. (2017). Osteoarthritis. In: Oliveira, J., Reis, R. (eds) Regenerative Strategies for the Treatment of Knee Joint Disabilities. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 21. Springer, Cham. https://doi.org/10.1007/978-3-319-44785-8_4

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