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Image Reconstruction in a Manifold of Image Patches: Application to Whole-Fetus Ultrasound Imaging

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Machine Learning for Medical Image Reconstruction (MLMIR 2019)

Abstract

We propose an image reconstruction framework to combine a large number of overlapping image patches into a fused reconstruction of the object of interest, that is robust to inconsistencies between patches (e.g. motion artefacts) without explicitly modelling them. This is achieved through two mechanisms: first, manifold embedding, where patches are distributed on a manifold with similar patches (where similarity is defined only in the region where they overlap) closer to each other. As a result, inconsistent patches are set far apart in the manifold. Second, fusion, where a sample in the manifold is mapped back to image space, combining features from all patches in the region of the sample.

For the manifold embedding mechanism, a new method based on a Convolutional Variational Autoencoder (\(\beta \)-VAE) is proposed, and compared to classical manifold embedding techniques: linear (Multi Dimensional Scaling) and non-linear (Laplacian Eigenmaps). Experiments using synthetic data and on real fetal ultrasound images yield fused images of the whole fetus where, in average, \(\beta \)-VAE outperforms all the other methods in terms of preservation of patch information and overall image quality.

This work was supported by the Wellcome Trust IEH Award [102431]. The authors acknowledge financial support from the Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy’s & St Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trust.

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Gomez, A. et al. (2019). Image Reconstruction in a Manifold of Image Patches: Application to Whole-Fetus Ultrasound Imaging. In: Knoll, F., Maier, A., Rueckert, D., Ye, J. (eds) Machine Learning for Medical Image Reconstruction. MLMIR 2019. Lecture Notes in Computer Science(), vol 11905. Springer, Cham. https://doi.org/10.1007/978-3-030-33843-5_21

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  • DOI: https://doi.org/10.1007/978-3-030-33843-5_21

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