Skip to main content

Depression, Diabetes-Related Distress, and Anxiety in Pediatric Diabetes

  • Chapter
  • First Online:
Behavioral Diabetes

Abstract

In the context of pediatric diabetes, depression and anxiety are associated with the direct medical management of diabetes and with social and family functioning. Data indicate that youth who experience depression and/or anxiety also suffer from an increased risk for negative health outcomes, and these risks are related to the psychological distress and perceived burden of daily diabetes management. Family factors such as poor cohesion, parental criticism, and family psychiatric history may be associated with increased symptoms of depression and anxiety. Family-based interventions that integrate education about diabetes in addition to traditional therapy strategies are effective for ameliorating depression and anxiety. Regular screening during outpatient diabetes clinics for depression and anxiety can help to identify youth with diabetes in need of psychological services. Consideration of the family and social environments in which children live is important to optimizing care. The literature for youth with type 2 diabetes is more limited than for youth with type 1, and further work to understand the etiology of symptoms and appropriate interventions is necessary.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Al Hayek, A. A., Robert, A. A., Braham, R. B., Issa, B. A., & Al Sabaan, F. S. (2015). Predictive risk factors for fear of hypoglycemia and anxiety-related emotional disorders among adolescents with type 1 diabetes. Medical Principles and Practice, 24(3), 222–230.

    Article  PubMed  PubMed Central  Google Scholar 

  • Almandil, N. B., Liu, Y., Murray, M. L., Besag, F. M., Aitchison, K. J., & Wong, I. C. (2013). Weight gain and other metabolic adverse effects associated with atypical antipsychotic treatment of children and adolescents: A systematic review and meta-analysis. Pediatric Drugs, 15(2), 139–150.

    Article  PubMed  Google Scholar 

  • American Diabetes Association. (2017). 12. Children and adolescents. Diabetes Care, 40(Supplement 1), S105–S113.

    Article  Google Scholar 

  • Anderson, B. J., Auslander, W. F., Jung, K. C., Miller, J. P., & Santiago, J. V. (1990). Assessing family sharing of diabetes responsibilities. Journal of Pediatric Psychology, 15(4), 477–492.

    Article  PubMed  Google Scholar 

  • Anderson, B. J., & Coyne, J. C. (1991). “Miscarried helping” in the families of children and adolescents with chronic diseases. In Advances in child health psychology (pp. 167–177). Gainesville, FL: University of Florida Press.

    Google Scholar 

  • Anderson, E. R., & Mayes, L. C. (2010). Race/ethnicity and internalizing disorders in youth: A review. Clinical Psychology Review, 30(3), 338–348.

    Article  PubMed  Google Scholar 

  • Arnett, J. J., Žukauskienė, R., & Sugimura, K. (2014). The new life stage of emerging adulthood at ages 18–29 years: Implications for mental health. The Lancet Psychiatry, 1(7), 569–576.

    Article  PubMed  Google Scholar 

  • Baeza, I., Vigo, L., de la Serna, E., Calvo-Escalona, R., Merchán-Naranjo, J., Rodríguez-Latorre, P., … Castro-Fornieles, J. (2017). The effects of antipsychotics on weight gain, weight-related hormones and homocysteine in children and adolescents: A 1-year follow-up study. European Child & Adolescent Psychiatry, 26(1), 35–46.

    Article  Google Scholar 

  • Bernstein, C. M., Stockwell, M. S., Gallagher, M. P., Rosenthal, S. L., & Soren, K. (2013). Mental health issues in adolescents and young adults with type 1 diabetes prevalence and impact on glycemic control. Clinical Pediatrics, 52(1), 10–15.

    Article  PubMed  Google Scholar 

  • Boland, E. A., Grey, M., Mezger, J. A., & Tamborlane, W. V. (1999). A summer vacation from diabetes: Evidence from a clinical trial. The Diabetes Educator, 25(1), 31–40.

    Article  PubMed  Google Scholar 

  • Boogerd, E. A., Damhuis, A., van Alfen-van der Velden, J. A., Steeghs, M. C., Noordam, C., Verhaak, C. M., & Vermaes, I. P. (2015). Assessment of psychosocial problems in children with type 1 diabetes and their families: The added value of using standardised questionnaires in addition to clinical estimations of nurses and paediatricians. Journal of Clinical Nursing, 24(15–16), 2143–2151.

    Article  PubMed  Google Scholar 

  • Briery, B. G., & Rabian, B. (1999). Psychosocial changes associated with participation in a pediatric summer camp. Journal of Pediatric Psychology, 24(2), 183–190.

    Article  PubMed  Google Scholar 

  • Broadhurst, P. L. (1959). The interaction of task difficulty and motivation: The Yerkes-Dodson Law revived. Acta Psychologica, 16, 321–338.

    Article  Google Scholar 

  • Brown, L. C., Majumdar, S. R., Newman, S. C., & Johnson, J. A. (2005). History of depression increases risk of type 2 diabetes in younger adults. Diabetes Care, 28(5), 1063–1067.

    Article  PubMed  Google Scholar 

  • Butner, J., Berg, C. A., Osborn, P., Butler, J. M., Godri, C., Fortenberry, K. T., & Wysocki, D. J. (2009). Parent–adolescent discrepancies in adolescents’ competence and the balance of adolescent autonomy and adolescent and parent well-being in the context of type 1 diabetes. Developmental Psychology, 45(3), 835.

    Article  PubMed  PubMed Central  Google Scholar 

  • Butwicka, A., Frisén, L., Almqvist, C., Zethelius, B., & Lichtenstein, P. (2015). Risks of psychiatric disorders and suicide attempts in children and adolescents with type 1 diabetes: A population-based cohort study. Diabetes Care, 38(3), 453–459.

    Article  PubMed  PubMed Central  Google Scholar 

  • Butwicka, A., Zalepa, A., Fendler, W., Szadkowska, A., & Mlynarski, W. (2013). Maternal depressive symptoms predict acute hospitalization among children with type 1 diabetes. Pediatric Diabetes, 14(4), 288–294.

    Article  PubMed  Google Scholar 

  • Calles, J. L. (2007). Depression in children and adolescents. Primary Care: Clinics in Office Practice, 34(2), 243–258.

    Article  PubMed  Google Scholar 

  • Cameron, L. D., Young, M. J., & Wiebe, D. J. (2007). Maternal trait anxiety and diabetes control in adolescents with type 1 diabetes. Journal of Pediatric Psychology, 32(7), 733–744.

    Article  PubMed  Google Scholar 

  • Cooper, W. O., Hickson, G. B., Fuchs, C., Arbogast, P. G., & Ray, W. A. (2004). New users of antipsychotic medications among children enrolled in TennCare. Archives of Pediatrics & Adolescent Medicine, 158(8), 753–759.

    Article  Google Scholar 

  • Copeland, K. C., Zeitler, P., Geffner, M., Guandalini, C., Higgins, J., Hirst, K., & Pyle, L. (2011). Characteristics of adolescents and youth with recent-onset type 2 diabetes: The TODAY cohort at baseline. The Journal of Clinical Endocrinology & Metabolism, 96(1), 159–167.

    Article  Google Scholar 

  • Corathers, S. D., Kichler, J., Jones, N. H. Y., Houchen, A., Jolly, M., Morwessel, N., & Hood, K. K. (2013). Improving depression screening for adolescents with type 1 diabetes. Pediatrics, 132(5), e1395–e1402.

    Article  PubMed  Google Scholar 

  • Cunningham, N. R., Vesco, A. T., Dolan, L. M., & Hood, K. K. (2011). From caregiver psychological distress to adolescent glycemic control: The mediating role of perceived burden around diabetes management. Journal of Pediatric Psychology, 36(2), 196–205. https://doi.org/10.1093/jpepsy/jsq071

    Article  PubMed  Google Scholar 

  • de Wit, M., & Snoek, F. J. (2011). Depressive symptoms and unmet psychological needs of Dutch youth with type 1 diabetes: Results of a web-survey. Pediatric Diabetes, 12(3pt1), 172–176.

    Article  PubMed  Google Scholar 

  • dos Santos, M. A. B., Ceretta, L. B., Réus, G. Z., Abelaira, H. M., Jornada, L. K., Schwalm, M. T., & Quevedo, J. (2014). Anxiety disorders are associated with quality of life impairment in patients with insulin-dependent type 2 diabetes: A case-control study. Revista Brasileira de Psiquiatria, 36(4), 298–304.

    Article  PubMed  Google Scholar 

  • Dabelea, D., DeGroat, J., Sorrelman, C., Glass, M., Percy, C. A., Avery, C., & Testaverde, L. (2009). Diabetes in Navajo youth. Diabetes Care, 32(Supplement 2), S141–S147.

    Article  PubMed  PubMed Central  Google Scholar 

  • De Groot, M., Anderson, R., Freedland, K., Clouse, R., & Lustman, P. J. (2001). Association of diabetes complications and depression in type 1 and type 2 diabetes: A meta-analysis. Diabetes, 49(5), A63.

    Google Scholar 

  • Delamater, A. M., de Wit, M., McDarby, V., Malik, J., & Acerini, C. L. (2014). Psychological care of children and adolescents with type 1 diabetes. Pediatric Diabetes, 15(S20), 232–244.

    Article  PubMed  Google Scholar 

  • Delamater, A. M., de Wit, M., McDarby, V., Malik, J., Hilliard, M. E., Northam, E., & Acerini, C. L. (2018). ISPAD clinical practice consensus guidelines: Psychological care of children and adolescents with type 1 diabetes. Pediatric Diabetes, 19(Supplement 27), 237–249. https://doi.org/10.1111/pedi.12736

    Article  PubMed  Google Scholar 

  • Duke, D. C., Geffken, G. R., Lewin, A. B., Williams, L. B., Storch, E. A., & Silverstein, J. H. (2008). Glycemic control in youth with type 1 diabetes: Family predictors and mediators. Journal of Pediatric Psychology, 33(7), 719–727.

    Article  PubMed  Google Scholar 

  • Faulkner, M. S., & Chang, L. I. (2007). Family influence on self-care, quality of life, and metabolic control in school-age children and adolescents with type 1 diabetes. Journal of Pediatric Nursing, 22(1), 59–68.

    Article  PubMed  Google Scholar 

  • Fisher, L., Gonzalez, J. S., & Polonsky, W. H. (2014). The confusing tale of depression and distress in patients with diabetes: A call for greater clarity and precision. Diabetic Medicine, 31(7), 764–772.

    Article  PubMed  PubMed Central  Google Scholar 

  • Fisher, L., Hessler, D. M., Polonsky, W. H., Masharani, U., Peters, A. L., Blumer, I., & Strycker, L. A. (2016). Prevalence of depression in type 1 diabetes and the problem of over-diagnosis. Diabetic Medicine, 33, 1590.

    Article  PubMed  Google Scholar 

  • Fisher, L., Mullan, J. T., Arean, P., Glasgow, R. E., Hessler, D., & Masharani, U. (2010). Diabetes distress but not clinical depression or depressive symptoms is associated with glycemic control in both cross-sectional and longitudinal analyses. Diabetes Care, 33(1), 23–28.

    Article  PubMed  Google Scholar 

  • Fisher, L., Skaff, M. M., Mullan, J. T., Arean, P., Glasgow, R., & Masharani, U. (2008). A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with type 2 diabetes. Diabetic Medicine, 25(9), 1096–1101.

    Article  PubMed  PubMed Central  Google Scholar 

  • Galling, B., Roldán, A., Nielsen, R. E., Nielsen, J., Gerhard, T., Carbon, M., & Kahl, K. G. (2016). Type 2 diabetes mellitus in youth exposed to antipsychotics: A systematic review and meta-analysis. JAMA Psychiatry, 73(3), 247–259.

    Article  PubMed  Google Scholar 

  • Garrison, M. M., Katon, W. J., & Richardson, L. P. (2005). The impact of psychiatric comorbidities on readmissions for diabetes in youth. Diabetes Care, 28(9), 2150–2154.

    Article  PubMed  Google Scholar 

  • Gonder-Frederick, L., Nyer, M., Shepard, J. A., Vajda, K., & Clarke, W. (2011). Assessing fear of hypoglycemia in children with type 1 diabetes and their parents. Diabetes Management, 1(6), 627–639.

    Article  PubMed  Google Scholar 

  • Gonder-Frederick, L. A., Fisher, C. D., Ritterband, L. M., Cox, D. J., Hou, L., DasGupta, A. A., & Clarke, W. L. (2006). Predictors of fear of hypoglycemia in adolescents with type 1 diabetes and their parents. Pediatric Diabetes, 7(4), 215–222.

    Article  PubMed  Google Scholar 

  • Grey, M., Boland, E. A., Davidson, M., Li, J., & Tamborlane, W. V. (2000). Coping skills training for youth with diabetes mellitus has long-lasting effects on metabolic control and quality of life. The Journal of Pediatrics, 137(1), 107–113.

    Article  PubMed  Google Scholar 

  • Grey, M., Cameron, M. E., Lipman, T. H., & Thurber, F. W. (1995). Psychosocial status of children with diabetes in the first 2 years after diagnosis. Diabetes Care, 18(10), 1330–1336.

    Article  PubMed  Google Scholar 

  • Grey, M., Whittemore, R., Jaser, S., Ambrosino, J., Lindemann, E., Liberti, L., & Dziura, J. (2009). Effects of coping skills training in school-age children with type 1 diabetes. Research in Nursing & Health, 32(4), 405–418.

    Article  Google Scholar 

  • Grey, M., Whittemore, R., Jeon, S., Murphy, K., Faulkner, M. S., Delamater, A., & TeenCope Study Group. (2013). Internet psycho-education programs improve outcomes in youth with type 1 diabetes. Diabetes Care, 36(9), 2475–2482.

    Article  PubMed  PubMed Central  Google Scholar 

  • Grey, M., Whittemore, R., & Tamborlane, W. (2002). Depression in type 1 diabetes in children: Natural history and correlates. Journal of Psychosomatic Research, 53(4), 907–911.

    Article  PubMed  Google Scholar 

  • Gross, R., Olfson, M., Gameroff, M. J., Carasquillo, O., Shea, S., Feder, A., & Weissman, M. M. (2005). Depression and glycemic control in Hispanic primary care patients with diabetes. Journal of General Internal Medicine, 20(5), 460–466.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hagger, V., Hendrieckx, C., Sturt, J., Skinner, T. C., & Speight, J. (2016). Diabetes distress among adolescents with type 1 diabetes: A systematic review. Current Diabetes Reports, 16(1), 9.

    Article  PubMed  Google Scholar 

  • Hains, A. A., Davies, W. H., Parton, E., & Silverman, A. H. (2001). Brief report: A cognitive behavioral intervention for distressed adolescents with type I diabetes. Journal of Pediatric Psychology, 26(1), 61–66.

    Article  PubMed  Google Scholar 

  • Hannon, T. S., Rofey, D. L., Lee, S., & Arslanian, S. A. (2013). Depressive symptoms and metabolic markers of risk for type 2 diabetes in obese adolescents. Pediatric Diabetes, 14(7), 497–503.

    Article  PubMed  Google Scholar 

  • Harris, M. A., Freeman, K. A., & Duke, D. C. (2015). Seeing is believing: using Skype to improve diabetes outcomes in youth. Diabetes Care, 38(8), 1427–1434.

    Google Scholar 

  • Hassan, K., Loar, R., Anderson, B. J., & Heptulla, R. A. (2006). The role of socioeconomic status, depression, quality of life, and glycemic control in type 1 diabetes mellitus. The Journal of Pediatrics, 149(4), 526–531.

    Article  PubMed  Google Scholar 

  • Helgeson, V. S., Siminerio, L., Escobar, O., & Becker, D. (2009). Predictors of metabolic control among adolescents with diabetes: A 4-year longitudinal study. Journal of Pediatric Psychology, 34(3), 254–270.

    Article  PubMed  Google Scholar 

  • Herzer, M., & Hood, K. K. (2009). Anxiety symptoms in adolescents with type 1 diabetes: association with blood glucose monitoring and glycemic control. Journal of Pediatric Psychology, 35(4), 415–425. https://doi.org/10.1093/jpepsy/jsp063

    Article  PubMed  PubMed Central  Google Scholar 

  • Herzer, M., Vesco, A., Ingerski, L. M., Dolan, L. M., & Hood, K. K. (2011). Explaining the family conflict-glycemic control link through psychological variables in adolescents with type 1 diabetes. Journal of Behavioral Medicine, 34(4), 268–274.

    Article  PubMed  Google Scholar 

  • Hilliard, M. E., Herzer, M., Dolan, L. M., & Hood, K. K. (2011). Psychological screening in adolescents with type 1 diabetes predicts outcomes one year later. Diabetes Research and Clinical Practice, 94(1), 39–44.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hilliard, M. E., Wu, Y. P., Rausch, J., Dolan, L. M., & Hood, K. K. (2013). Predictors of deteriorations in diabetes management and control in adolescents with type 1 diabetes. Journal of Adolescent Health, 52(1), 28-34.

    Google Scholar 

  • Hislop, A. L., Fegan, P. G., Schlaeppi, M. J., Duck, M., & Yeap, B. B. (2008). Prevalence and associations of psychological distress in young adults with type 1 diabetes. Diabetic Medicine, 25(1), 91–96.

    Article  PubMed  Google Scholar 

  • Hood, K. K., Beavers, D. P., Yi-Frazier, J., Bell, R., Dabelea, D., Mckeown, R. E., & Lawrence, J. M. (2014). Psychosocial burden and glycemic control during the first 6 years of diabetes: Results from the SEARCH for diabetes in youth study. Journal of Adolescent Health, 55(4), 498–504.

    Article  Google Scholar 

  • Hood, K. K., Huestis, S., Maher, A., Butler, D., Volkening, L., & Laffel, L. M. (2006). Depressive symptoms in children and adolescents with type 1 diabetes. Diabetes Care, 29(6), 1389–1389.

    Article  PubMed  Google Scholar 

  • Hood, K. K., Rausch, J. R., & Dolan, L. M. (2011). Depressive symptoms predict change in glycemic control in adolescents with type 1 diabetes: Rates, magnitude, and moderators of change. Pediatric Diabetes, 12(8), 718–723.

    Article  PubMed  Google Scholar 

  • Jaser, S. S., & Grey, M. (2010). A pilot study of observed parenting and adjustment in adolescents with type 1 diabetes and their mothers. Journal of Pediatric Psychology, 35(7), 738–747.

    Article  PubMed  Google Scholar 

  • Jaser, S. S., Holl, M. G., Jefferson, V., & Grey, M. (2009). Correlates of depressive symptoms in urban youth at risk for type 2 diabetes mellitus. Journal of School Health, 79(6), 286–292.

    Article  Google Scholar 

  • Jaser, S. S., Whittemore, R., Ambrosino, J. M., Lindemann, E., & Grey, M. (2008). Mediators of depressive symptoms in children with type 1 diabetes and their mothers. Journal of Pediatric Psychology, 33(5), 509–519.

    Article  PubMed  Google Scholar 

  • Jaycox, L. H., Stein, B. D., Paddock, S., Miles, J. N., Chandra, A., Meredith, L. S., & Burnam, M. A. (2009). Impact of teen depression on academic, social, and physical functioning. Pediatrics, 124(4), e596–e605.

    Article  PubMed  Google Scholar 

  • Johnson, B., Eiser, C., Young, V., Brierley, S., & Heller, S. (2013). Prevalence of depression among young people with type 1 diabetes: A systematic review. Diabetic Medicine, 30(2), 199–208.

    Article  PubMed  Google Scholar 

  • Katz, L. L., Anderson, B. J., McKay, S. V., Izquierdo, R., Casey, T. L., Higgins, L. A., … Nadeau, K. J. (2016). Correlates of medication adherence in the TODAY cohort of youth with type 2 diabetes. Diabetes Care, 39(11), 1956–1962.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kumra, S., Oberstar, J. V., Sikich, L., Findling, R. L., McClellan, J. M., Vinogradov, S., & Schulz, S. C. (2008). Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia. Schizophrenia Bulletin, 34(1), 60–71.

    Article  PubMed  Google Scholar 

  • Lawrence, J. M., Standiford, D. A., Loots, B., Klingensmith, G. J., Williams, D. E., Ruggiero, A., & McKeown, R. E. (2006). Prevalence and correlates of depressed mood among youth with diabetes: The SEARCH for diabetes in youth study. Pediatrics, 117(4), 1348–1358.

    Article  PubMed  Google Scholar 

  • Li, C., Barker, L., Ford, E. S., Zhang, X., Strine, T. W., & Mokdad, A. H. (2008). Diabetes and anxiety in US adults: Findings from the 2006 behavioral risk factor surveillance system. Diabetic Medicine, 25(7), 878–881. https://doi.org/10.1111/j.1464-5491.2008.02477.x

    Article  PubMed  Google Scholar 

  • Lustman, P. J., Anderson, R. J., Freedland, K. E., De Groot, M., Carney, R. M., & Clouse, R. E. (2000). Depression and poor glycemic control: A meta-analytic review of the literature. Diabetes Care, 23(7), 934–942.

    Article  PubMed  Google Scholar 

  • Markowitz, S. M., Gonzalez, J. S., Wilkinson, J. L., & Safren, S. A. (2011). A review of treating depression in diabetes: Emerging findings. Psychosomatics, 52(1), 1–18.

    Article  PubMed  PubMed Central  Google Scholar 

  • Marrast, L., Himmelstein, D. U., & Woolhandler, S. (2016). Racial and ethnic disparities in mental health care for children and young adults: A national study. International Journal of Health Services, 46(4), 810–824.

    Article  PubMed  Google Scholar 

  • McGrady, M. E., & Hood, K. K. (2013). Cognitive–behavioral therapy for adolescents with type 1 diabetes and subclinical depressive symptoms. Diabetes Management, 3(3), 207–215.

    Article  Google Scholar 

  • McGrady, M. E., Laffel, L., Drotar, D., Repaske, D., & Hood, K. K. (2009). Depressive symptoms and glycemic control in adolescents with type 1 diabetes. Diabetes Care, 32(5), 804–806.

    Article  PubMed  PubMed Central  Google Scholar 

  • Miller, V. A., & Drotar, D. (2003). Discrepancies between mother and adolescent perceptions of diabetes-related decision-making autonomy and their relationship to diabetes-related conflict and adherence to treatment. Journal of Pediatric Psychology, 28(4), 265–274.

    Article  PubMed  Google Scholar 

  • Monaghan, M., Horn, I. B., Alvarez, V., Cogen, F. R., & Streisand, R. (2012). Authoritative parenting, parenting stress, and self-care in pre-adolescents with type 1 diabetes. Journal of Clinical Psychology in Medical Settings, 19(3), 255–261.

    Article  PubMed  PubMed Central  Google Scholar 

  • Musselman, D. L., Betan, E., Larsen, H., & Phillips, L. S. (2003). Relationship of depression to diabetes types 1 and 2: Epidemiology, biology, and treatment. Biological Psychiatry, 54(3), 317–329.

    Article  PubMed  Google Scholar 

  • Naar-King, S., Idalski, A., Ellis, D., Frey, M., Templin, T., Cunningham, P. B., & Cakan, N. (2006). Gender differences in adherence and metabolic control in urban youth with poorly controlled type 1 diabetes: The mediating role of mental health symptoms. Journal of Pediatric Psychology, 31(8), 793–802.

    Article  PubMed  Google Scholar 

  • Nadeau, K., & Dabelea, D. (2008). Epidemiology of type 2 diabetes in children and adolescents. Endocrine Research, 33(1–2), 35–58.

    Article  PubMed  Google Scholar 

  • Naicker, K., Johnson, J. A., Skogen, J. C., Manuel, D., Øverland, S., Silvertsen, B., & Colman, I. (2017). Type 2 Diabetes and Comorbid Symptoms of depression and anxiety: Longitudinal associations with mortality risk. Diabetes Care. https://doi.org/10.2337/dc16-2018

    Article  PubMed  Google Scholar 

  • Patton, S. R., Dolan, L. M., & Powers, S. W. (2006). Mealtime interactions relate to dietary adherence and glycemic control in young children with type 1 diabetes. Diabetes Care, 29(5), 1002–1006.

    Article  PubMed  Google Scholar 

  • Pereira, M. G., Berg-Cross, L., Almeida, P., & Machado, J. C. (2008). Impact of family environment and support on adherence, metabolic control, and quality of life in adolescents with diabetes. International Journal of Behavioral Medicine, 15(3), 187–193.

    Article  PubMed  Google Scholar 

  • Price, J. H., Khubchandani, J., McKinney, M., & Braun, R. (2013). Racial/ethnic disparities in chronic diseases of youths and access to health care in the United States. BioMed Research International, 2013, 1.

    Article  Google Scholar 

  • Reiss, F. (2013). Socioeconomic inequalities and mental health problems in children and adolescents: A systematic review. Social Science & Medicine, 90, 24–31.

    Article  Google Scholar 

  • Reynolds, K. A., & Helgeson, V. S. (2011). Children with diabetes compared to peers: Depressed? Distressed? Annals of Behavioral Medicine, 42(1), 29–41.

    Article  PubMed  Google Scholar 

  • Riley, A. R., Duke, D. C., Freeman, K. A., Hood, K. K., & Harris, M. A. (2015). Depressive symptoms in a trial behavioral family systems therapy for diabetes: A post hoc analysis of change. Diabetes Care, 38(8), 1435–1440.

    Article  PubMed  Google Scholar 

  • Rosselló, J. M., & Jiménez-Chafey, M. I. (2006). Cognitive-behavioral group therapy for depression in adolescents with diabetes: A pilot study. Interamerican Journal of Psychology, 40(2), 219–226.

    Google Scholar 

  • Rubin, R. R., Ma, Y., Marrero, D. G., Peyrot, M., Barrett-Connor, E. L., Kahn, S. E., … Knowler, W. C. (2008). Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program. Diabetes Care, 31(3), 420–426.

    Article  PubMed  Google Scholar 

  • Schwartz, D. D., Cline, V. D., Axelrad, M. E., & Anderson, B. J. (2011). Feasibility, acceptability, and predictive validity of a psychosocial screening program for children and youth newly diagnosed with type 1 diabetes. Diabetes Care, 34(2), 326–331.

    Article  PubMed  PubMed Central  Google Scholar 

  • Shomaker, L. B., Tanofsky-Kraff, M., Stern, E. A., Miller, R., Zocca, J. M., Field, S. E., & Yanovski, J. A. (2011). Longitudinal study of depressive symptoms and progression of insulin resistance in youth at risk for adult obesity. Diabetes Care, 34(11), 2458–2463.

    Article  PubMed  PubMed Central  Google Scholar 

  • Shomaker, L. B., Tanofsky-Kraff, M., Young-Hyman, D., Han, J. C., Yanoff, L. B., Brady, S. M., & Yanovski, J. A. (2010). Psychological symptoms and insulin sensitivity in adolescents. Pediatric Diabetes, 11(6), 417–423.

    Article  PubMed  Google Scholar 

  • Shomaker, L. B., Kelly, N. R., Pickworth, C. K., Cassidy, O. L., Radin, R. M., Shank, L. M., ... & Demidowich, A. P. (2016). A randomized controlled trial to prevent depression and ameliorate insulin resistance in adolescent girls at risk for type 2 diabetes. Annals of Behavioral Medicine, 50(5), 762–774.

    Google Scholar 

  • Shulman, S., & Connolly, J. (2013). The challenge of romantic relationships in emerging adulthood: Reconceptualization of the field. Emerging Adulthood, 1(1), 27–39.

    Article  Google Scholar 

  • Silverstein, J., Cheng, P., Ruedy, K. J., Kollman, C., Beck, R. W., Klingensmith, G. J., … Cengiz, E. (2015). Depressive symptoms in youth with type 1 or type 2 diabetes: Results of the pediatric diabetes consortium screening assessment of depression in diabetes study. Diabetes Care, 38(12), 2341–2343.

    Article  PubMed  Google Scholar 

  • Singh, E., Farruggia, S. P., & Peterson, E. R. (2013). Adolescents with diabetes: Support from healthcare teams and families. International Journal of Adolescent Medicine and Health, 25(1), 91–96.

    Article  PubMed  Google Scholar 

  • Skinner, T. C., John, M., & Hampson, S. E. (2000). Social support and personal models of diabetes as predictors of self-care and well-being: A longitudinal study of adolescents with diabetes. Journal of Pediatric Psychology, 25(4), 257–267.

    Article  PubMed  Google Scholar 

  • Sood, E. D., Pendley, J. S., Delamater, A. M., Rohan, J. M., Pulgaron, E. R., & Drotar, D. (2012). Mother–father informant discrepancies regarding diabetes management: Associations with diabetes-specific family conflict and glycemic control. Health Psychology, 31(5), 571.

    Article  PubMed  PubMed Central  Google Scholar 

  • Strickland, B. B., Jones, J. R., Ghandour, R. M., Kogan, M. D., & Newacheck, P. W. (2011). The medical home: health care access and impact for children and youth in the United States. Pediatrics. https://doi.org/10.1542/peds.2009-3555

    Article  PubMed  Google Scholar 

  • Suglia, S. F., Demmer, R. T., Wahi, R., Keyes, K. M., & Koenen, K. C. (2016). Depressive symptoms during adolescence and young adulthood and the development of type 2 diabetes mellitus. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwv149

    Article  PubMed  PubMed Central  Google Scholar 

  • Tabák, A. G., Akbaraly, T. N., Batty, G. D., & Kivimäki, M. (2014). Depression and type 2 diabetes: A causal association? The Lancet Diabetes & Endocrinology, 2(3), 236–245.

    Article  Google Scholar 

  • Twenge, J. M., & Nolen-Hoeksema, S. (2002). Age, gender, race, socioeconomic status, and birth cohort difference on the children’s depression inventory: A meta-analysis. Journal of Abnormal Psychology, 111(4), 578–588.

    Article  PubMed  Google Scholar 

  • Van der Feltz-Cornelis, C. M., Nuyen, J., Stoop, C., Chan, J., Jacobson, A. M., Katon, W., & Sartorius, N. (2010). Effect of interventions for major depressive disorder and significant depressive symptoms in patients with diabetes mellitus: A systematic review and meta-analysis. General Hospital Psychiatry, 32(4), 380–395.

    Article  PubMed  Google Scholar 

  • Vesco, A. T., Anderson, B. J., Laffel, L. M., Dolan, L. M., Ingerski, L. M., & Hood, K. K. (2010). Responsibility sharing between adolescents with type 1 diabetes and their caregivers: Importance of adolescent perceptions on diabetes management and control. Journal of Pediatric Psychology, 35(10), 1168–1177.

    Article  PubMed  PubMed Central  Google Scholar 

  • Weissberg-Benchell, J., & Antisdel-Lomaglio, J. (2011). Diabetes-specific emotional distress among adolescents: Feasibility, reliability, and validity of the problem areas in diabetes-teen version. Pediatric Diabetes, 12(4pt1), 341–344.

    Article  PubMed  Google Scholar 

  • Weissman, M. M., Bland, R. C., Canino, G. J., Faravelli, C., Greenwald, S., Hwu, H. G., & Lépine, J. P. (1996). Cross-national epidemiology of major depression and bipolar disorder. JAMA, 276(4), 293–299.

    Article  PubMed  Google Scholar 

  • Whittemore, R., Kanner, S., Singleton, S., Hamrin, V., Chiu, J., & Grey, M. (2002). Correlates of depressive symptoms in adolescents with type 1 diabetes. Pediatric Diabetes, 3(3), 135–143.

    Article  PubMed  Google Scholar 

  • Whitworth, S. R., Bruce, D. G., Starkstein, S. E., Davis, W. A., Davis, T. M. E., & Bucks, R. S. (2016). Lifetime depression and anxiety increase prevalent psychological symptoms and worsen glycemic control in type 2 diabetes: The Fremantle diabetes study phase II. Diabetes Research and Clinical Practice, 122, 190–197.

    Article  PubMed  Google Scholar 

  • Wiebe, D. J., Berg, C. A., Korbel, C., Palmer, D. L., Beveridge, R. M., Upchurch, R., & Donaldson, D. L. (2005). Children’s appraisals of maternal involvement in coping with diabetes: Enhancing our understanding of adherence, metabolic control, and quality of life across adolescence. Journal of Pediatric Psychology, 30(2), 167–178.

    Article  PubMed  Google Scholar 

  • Williams, L. B., Laffel, L. M. B., & Hood, K. K. (2009). Diabetes-specific family conflict and psychological distress in paediatric type 1 diabetes. Diabetic Medicine, 26(9), 908–914.

    Article  PubMed  PubMed Central  Google Scholar 

  • Wu, Y. P., Hilliard, M. E., Rausch, J., Dolan, L. M., & Hood, K. K. (2013). Family involvement with the diabetes regimen in young people: The role of adolescent depressive symptoms. Diabetic Medicine, 30(5), 596–602.

    Article  PubMed  PubMed Central  Google Scholar 

  • Wysocki, T., Harris, M. A., Buckloh, L. M., Mertlich, D., Lochrie, A. S., Mauras, N., & White, N. H. (2007). Randomized trial of behavioral family systems therapy for diabetes maintenance of effects on diabetes outcomes in adolescents. Diabetes Care, 30(3), 555–560.

    Article  PubMed  Google Scholar 

  • Wysocki, T., Harris, M. A., Buckloh, L. M., Mertlich, D., Lochrie, A. S., Taylor, A., & White, N. H. (2006). Effects of behavioral family systems therapy for diabetes on adolescents’ family relationships, treatment adherence, and metabolic control. Journal of Pediatric Psychology, 31(9), 928–938.

    Article  PubMed  Google Scholar 

  • Wysocki, T., Harris, M. A., Buckloh, L. M., Mertlich, D., Lochrie, A. S., Taylor, A., & White, N. H. (2008). Randomized, controlled trial of behavioral family systems therapy for diabetes: Maintenance and generalization of effects on parent-adolescent communication. Behavior Therapy, 39(1), 33–46.

    Article  PubMed  Google Scholar 

  • Wysocki, T., Nansel, T. R., Holmbeck, G. N., Chen, R., Laffel, L., Anderson, B. J., & Weissberg-Benchell, J. (2009). Collaborative involvement of primary and secondary caregivers: Associations with youths’ diabetes outcomes. Journal of Pediatric Psychology, 34(8), 869–881.

    Article  PubMed  Google Scholar 

  • Young-Hyman, D., de Groot, M., Hill-Briggs, F., Gonzalez, J. S., Hood, K., & Peyrot, M. (2016). Psychosocial care for people with diabetes: A position statement of the American Diabetes Association. Diabetes Care, 39(12), 2126–2140.

    Article  PubMed  PubMed Central  Google Scholar 

  • Zenlea, I. S., Mednick, L., Rein, J., Quinn, M., Wolfsdorf, J., & Rhodes, E. T. (2014). Routine behavioral and mental health screening in young children with type 1 diabetes mellitus. Pediatric Diabetes, 15(5), 384–388.

    Article  PubMed  Google Scholar 

  • Zuddas, A., Zanni, R., & Usala, T. (2011). Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: A review of the randomized controlled studies. European Neuropsychopharmacology, 21(8), 600–620.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jill Weissberg-Benchell .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Evans, M.A., Vesco, A.T., Weissberg-Benchell, J. (2020). Depression, Diabetes-Related Distress, and Anxiety in Pediatric Diabetes. In: Delamater, A., Marrero, D. (eds) Behavioral Diabetes. Springer, Cham. https://doi.org/10.1007/978-3-030-33286-0_5

Download citation

Publish with us

Policies and ethics