Abstract
Current deep neural network based approaches to computed tomography (CT) metal artifact reduction (MAR) are supervised methods which rely heavily on synthesized data for training. However, as synthesized data may not perfectly simulate the underlying physical mechanisms of CT imaging, the supervised methods often generalize poorly to clinical applications. To address this problem, we propose, to the best of our knowledge, the first unsupervised learning approach to MAR. Specifically, we introduce a novel artifact disentanglement network that enables different forms of generations and regularizations between the artifact-affected and artifact-free image domains to support unsupervised learning. Extensive experiments show that our method significantly outperforms the existing unsupervised models for image-to-image translation problems, and achieves comparable performance to existing supervised models on a synthesized dataset. When applied to clinical datasets, our method achieves considerable improvements over the supervised models. The source code of this paper is publicly available at https://github.com/liaohaofu/adn.
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Gjesteby, L., et al.: Metal artifact reduction in CT: where are we after four decades? IEEE Access 4, 5826–5849 (2016)
Gjesteby, L., et al.: Deep neural network for CT metal artifact reduction with a perceptual loss function. In: Proceedings of the Fifth International Conference on Image Formation in X-Ray Computed Tomography (2018)
Goodfellow, I., et al.: Generative adversarial nets. In: Advances in Neural Information Processing Systems (2014)
Huang, X., Wang, J., Tang, F., Zhong, T., Zhang, Y.: Metal artifact reduction on cervical CT images by deep residual learning. Biomed. Eng. Online 17(1), 175 (2018)
Huang, X., Liu, M.-Y., Belongie, S., Kautz, J.: Multimodal unsupervised image-to-image translation. In: Ferrari, V., Hebert, M., Sminchisescu, C., Weiss, Y. (eds.) ECCV 2018. LNCS, vol. 11207, pp. 179–196. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01219-9_11
Lee, H.-Y., Tseng, H.-Y., Huang, J.-B., Singh, M., Yang, M.-H.: Diverse image-to-image translation via disentangled representations. In: Ferrari, V., Hebert, M., Sminchisescu, C., Weiss, Y. (eds.) ECCV 2018. LNCS, vol. 11205, pp. 36–52. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01246-5_3
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Ulyanov, D., Vedaldi, A., Lempitsky, V.S.: Deep image prior. In: The IEEE Conference on Computer Vision and Pattern Recognition (CVPR), June 2018
Wang, J., Zhao, Y., Noble, J.H., Dawant, B.M.: Conditional generative adversarial networks for metal artifact reduction in CT images of the ear. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11070, pp. 3–11. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00928-1_1
Yan, K., Wang, X., Lu, L., Summers, R.M.: DeepLesion: automated mining of large-scale lesion annotations and universal lesion detection with deep learning. J. Med. Imaging (2018)
Zhang, Y., Yu, H.: Convolutional neural network based metal artifact reduction in X-ray computed tomography. IEEE Trans. Med. Imaging 37(6), 1370–1381 (2018)
Zhu, J.Y., Park, T., Isola, P., Efros, A.A.: Unpaired image-to-image translation using cycle-consistent adversarial networks. In: The IEEE Conference on Computer Vision and Pattern Recognition (CVPR) (2017)
Zhu, J., Park, T., Isola, P., Efros, A.A.: Unpaired image-to-image translation using cycle-consistent adversarial networks. CoRR abs/1703.10593 (2017)
Acknowledgement
This work was supported in part by NSF award #1722847 and the Morris K. Udall Center of Excellence in Parkinson’s Disease Research by NIH.
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Liao, H., Lin, WA., Yuan, J., Zhou, S.K., Luo, J. (2019). Artifact Disentanglement Network for Unsupervised Metal Artifact Reduction. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11769. Springer, Cham. https://doi.org/10.1007/978-3-030-32226-7_23
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DOI: https://doi.org/10.1007/978-3-030-32226-7_23
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