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Nanotheranostics pp 229–244Cite as

Biosynthesized Metallic Nanoparticles as Emerging Cancer Theranostics Agents

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Abstract

Cancer is considered as a great health challenge liable for outstripped demises worldwide. Currently it is treated mainly by chemotherapy and radiotherapy. However, there is a perpetual demand for the development of novel therapeutic drugs to combat this devastating disease. In this regard nanomedicine can provide an alternative platform for its diagnosis and treatment but its conventional synthesis through physiochemical methods has several shortcomings like high cost, energy intensive, and toxicity concerns. Consequently, the green synthesis of biogenic metallic nanoparticles (MNPs) from plants provides an alternate paradigm which has been proved safer, eco-friendly, energy proficient, inexpensive, and less toxic in nature. Additionally, the green MNPs have multipurpose biomedical applications like drug delivery agents, anticancerous mediators, photothermal therapy, and bio-imaging. This chapter will provide ample information on the current status of green MNPs, its anticancerous mechanisms, and efficiency in cancer diagnosis. Other issues like polydispersity and toxicity are also highlighted. Keeping in view all of the challenges, the authors anticipate biogenic MNPs may contribute to shift the paradigm toward development of novel nanomedicine that can prove as biocompatible theranostic agents in near future.

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Authors and Affiliations

  1. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing, People’s Republic of China

    Muhammad Ovais

  2. University of Chinese Academy of Sciences, Beijing, People’s Republic of China

    Muhammad Ovais

  3. Department of Eastern Medicine and Surgery, Qarshi University, Lahore, Pakistan

    Ali Talha Khalil

  4. Department of Pharmacy, University of Malakand, Chakdara, Khyber Pakhtunkhwa, Pakistan

    Muhammad Ayaz

  5. Department of Life Sciences, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia

    Irshad Ahmad

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  1. Muhammad Ovais
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  2. Ali Talha Khalil
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  3. Muhammad Ayaz
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  4. Irshad Ahmad
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Correspondence to Muhammad Ovais .

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Editors and Affiliations

  1. Department of Biotechnology, Nanobiotechnology Laboratory, Amravati, Maharashtra, India, Department of Chemistry, Federal University of Piauí, Teresina, Piauí, Brazil

    Mahendra Rai

  2. Department of DMLS, University of Lahore, Islamabad, Pakistan

    Bushra Jamil

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Ovais, M., Khalil, A.T., Ayaz, M., Ahmad, I. (2019). Biosynthesized Metallic Nanoparticles as Emerging Cancer Theranostics Agents. In: Rai, M., Jamil, B. (eds) Nanotheranostics. Springer, Cham. https://doi.org/10.1007/978-3-030-29768-8_11

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