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The Scientific Rationale of Artificial Pacing

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Heart of the Matter

Part of the book series: Learning Materials in Biosciences ((LMB))

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Abstract

This chapter will comprehensively explore the evidence base and underlying scientific rationale for artificial pacemakers and implantable cardioverter defibrillators (ICDs). This will involve a discussion of the three main categories of artificial pacemakers and a broad overview of the pacing modes available, in addition to a comparison of single vs. dual chamber pacing. Then, the indications of ICDs in both the primary and secondary prevention of sudden cardiac death (SCD) will be examined, before we go on to explore the therapeutic potential of His bundle pacing and leadless pacemakers. In particular, this chapter will critically appraise several large studies, identifying the key factors to consider.

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Author information

Authors and Affiliations

  1. Brighton and Sussex Medical School, Brighton, UK

    Dominic Gyimah

  2. Imperial College London, London, UK

    Dominic Gyimah

  3. National Heart and Lung Institute, Imperial College London, London, UK

    Ahran D. Arnold & Zachary I. Whinnett

Authors
  1. Dominic Gyimah
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  2. Ahran D. Arnold
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  3. Zachary I. Whinnett
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Corresponding author

Correspondence to Ahran D. Arnold .

Editor information

Editors and Affiliations

  1. National Heart & Lung Institute, Imperial College London, London, UK

    Cesare Terracciano

  2. Imperial College London & St George’s Medical School, London, UK

    Samuel Guymer

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Gyimah, D., Arnold, A.D., Whinnett, Z.I. (2019). The Scientific Rationale of Artificial Pacing. In: Terracciano, C., Guymer, S. (eds) Heart of the Matter. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-24219-0_9

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