Abstract
Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) is the most common autoinflammatory disorder in children in many parts of the world
PFAPA should be considered in patients with a history of regular, most commonly 3–5-days long fever episodes with associated oropharyngeal symptoms
Children with PFAPA are well between episodes and show normal growth and development
PFAPA is a benign disorder that typically resolves spontaneously within 3 to 5 years after onset
Treatment is primarily symptomatic. Episodes occurring at a time inconvenient for the family can be aborted by a single dose of corticosteroids
Tonsillectomy is a treatment option in selected cases
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Rydenman, K., Berg, S., Wekell, P. (2019). Recurrent Fever and Sore Throat. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_104
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DOI: https://doi.org/10.1007/978-3-030-21262-9_104
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