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Actinomycetes: Its Realm in Nanotechnology

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Microbial Nanobionics

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

Abstract

The development of the eco-friendly procedures for the synthesis of nanoparticles has been thoroughly investigated in the field of nanotechnology. Biological synthesis of metal nanoparticles has been well achieved by different microorganisms including actinomycetes. They are a fascinating group of Gram-positive fungi-like bacteria with diverse biological activities and are considered as eco-friendly nano-factories for nanoparticle synthesis. Organism isolation from various sources and synthesis of nanoparticles follow characterization through different analytical methods for their stability, significant biocidal activity and anticancer properties. Regardless of the actinomycete potent activity, the quantity of metal nanoparticle synthesized never meets industrial needs. Thus by spading in in vitro studies, it may bridge towards the large-scale production of metal nanoparticle through bioprocess optimization and biological overexpression. This chapter focuses on the biological synthesis of metal nanoparticles and their application in medicine. In addition, the toxicity of these biogenic metal nanoparticles to human beings and environment is also included.

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References

  • Ahmad A, Senapati S, Khan MI, Kumar R, Ramani R, Srinivas V, Sastry M (2003a) Extracellular biosynthesis of monodisperse gold nano-particles by a novel extremophilic actinomycete Thermomonospora sp. Langmuir 19:3550–3553

    Article  CAS  Google Scholar 

  • Ahmad A, Senapati S, Khan MI, Kumar R, Ramani R, Srinivas V, Sastry M (2003b) Intracellular synthesis of gold nanoparticles by a novel alkalotolerant actinomycete, Rhodococcus species. Nanotechnology 14:824

    Article  CAS  Google Scholar 

  • Alani F, Moo-Young M, Anderson W (2012) Biosynthesis of silver nanoparticles by a new strain of Streptomyces sp. compared with Aspergillus fumigatus. World J Microbiol Biotechnol 28(3):1081–1086

    Article  CAS  PubMed  Google Scholar 

  • Anisa M, Daar AS, Singer PA (2003) Mind the gap’: science and ethics in nanotechnology. Nanotechnology 14(3):R9

    Article  Google Scholar 

  • Aziz N, Fatma T, Varma A, Prasad R (2014) Biogenic synthesis of silver nanoparticles using Scenedesmus abundans and evaluation of their antibacterial activity. J Nanopart: 689419. https://doi.org/10.1155/2014/689419

    Article  CAS  Google Scholar 

  • Aziz N, Faraz M, Pandey R, Sakir M, Fatma T, Varma A, Barman I, Prasad R (2015) Facile algae-derived route to biogenic silver nanoparticles: synthesis, antibacterial and photocatalytic properties. Langmuir 31:11605–11612. https://doi.org/10.1021/acs.langmuir.5b03081

    Article  CAS  PubMed  Google Scholar 

  • Aziz N, Pandey R, Barman I, Prasad R (2016) Leveraging the attributes of Mucor hiemalis-derived silver nanoparticles for a synergistic broad-spectrum antimicrobial platform. Front Microbiol 7:1984. https://doi.org/10.3389/fmicb.2016.01984

    Article  PubMed  PubMed Central  Google Scholar 

  • Aziz N, Faraz M, Sherwani MA, Fatma T, Prasad R (2019) Illuminating the anticancerous efficacy of a new fungal chassis for silver nanoparticle synthesis. Front Chem 7:65. https://doi.org/10.3389/fchem.2019.00065

  • Azizi S, Namvar F, Mahdavi M, Ahmad MB, Mohamad R (2013) Biosynthesis of silver nanoparticles using brown marine macroalga, Sargassum muticum aqueous extract. Mater 6:5942–5950

    Article  CAS  Google Scholar 

  • Balagurunathan R, Radhakrishnan M, Rajendran RB, Velmurugan D (2011) Biosynthesis of gold nanoparticles by actinomycete Streptomyces viridogens strain HM10. Indian J Biochem Biophys 48:331–335

    CAS  PubMed  Google Scholar 

  • Chauhan R, Kumar A, Abraham J (2013) A biological approach to the synthesis of silver nanoparticles with Streptomyces sp. JAR1 and its antimicrobial activity. Sci Pharm 81:607–621

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Das VL, Thomas R, Varghese RT, Soniya EV, Mathew J, Radhakrishnan EK (2014) Extracellular synthesis of silver nanoparticles by the Bacillus strain CS 11 isolated from industrialized area. 3Biotech 4:121–126

    Google Scholar 

  • Deepa S, Kanimozhi K, Panneerselvam A (2013) Antimicrobial activity of extracellularly synthesized silver nanoparticles from marine derived actinomycetes. Int J Curr Microbiol Appl Sci 2(9):223–230

    Google Scholar 

  • Durán N, Marcato PD, Alves OL, De Souza GIH, Esposito E (2005) Mechanistic aspects of biosynthesis of silver nanoparticles by several Fusarium oxysporum strains. J Nanobiotechnol 3:8

    Article  Google Scholar 

  • El-Rafie HM, El-Rafie MH, Zahran MK (2013) Green synthesis of silver nanoparticles using polysaccharides extracted from marine macro algae. Carbohydr Polym 96(2):403–410

    Article  CAS  PubMed  Google Scholar 

  • Gaikwad S, Birla S, Ingle A, Gade A, Marcato P, Rai M, Duran N (2013) Screening of different Fusarium species to select potential species for the synthesis of silver nanoparticles. J Braz Chem Soc 24(2):1974–1982

    CAS  Google Scholar 

  • Ghorbani HR (2013) Biosynthesis of silver nanoparticles using Salmonella typhimurium. J Nanostruct Chem 3:29

    Article  Google Scholar 

  • Honary S, Gharaei-Fathabad E, Barabadi H, Naghibi F (2013) Fungus-mediated synthesis of gold nanoparticles: a novel biological approach to nanoparticle synthesis. J Nanosci Nanotechnol 13(2):1427–1430

    Article  CAS  PubMed  Google Scholar 

  • Kalabegishvili T, Kirkesali E, Ginturi E, Rcheulishvili A, Murusidze I, Pataraya D, Gurielidze M, Bagdavadze N, Kuchava N, Gvarjaladze D, Lomidze L (2013) Synthesis of gold nanoparticles by new strains of thermophilic actinomycetes. Nano Stud 7:255–260

    Google Scholar 

  • Kapil P, Choudhary P, Samant L, Mukherjee S, Vaidya S, Chowdhary A (2015) Biosynthesis of nanoparticles: a review. Int J Pharm Sci Rev Res 30(1):219–226

    Google Scholar 

  • Karthik L, Kumar G, Vishnu Kirthi A, Rahuman AA, Bhaskara Rao KV (2014) Streptomyces sp. LK3 mediated synthesis of silver nanoparticles and its biomedical application. Bioprocess Biosyst Eng 37:261–267

    Article  CAS  PubMed  Google Scholar 

  • Khalil MMH, Ismail EH, El-Baghdady KZ, Mohamed D (2013) Green synthesis of silver nanoparticles using olive leaf extract and its antibacterial activity. Arab J Chem. https://doi.org/10.1016/j.arabjc.2013.04.007s

  • Manivasagan P, Venkatesan J, Senthilkumar K, Sivakumar K, Kim S (2013) Biosynthesis, antimicrobial and cytotoxic effect of silver nanoparticles using a novel Nocardiopsis sp. MBRC-1. Bio Med Res Int: 287638, 9 pages

    Google Scholar 

  • Mohan YM, Lee K, Premkumar T, Geckeler KE (2007) Hydrogel net-works as nanoreactors: a novel approach to silver nanoparticles for antibacterial applications. Polymer 48:158–164

    Article  CAS  Google Scholar 

  • Narasimha G, Janardhan A, Alzohairy M, Khadri H, Mallikarjuna K (2013) Extracellular synthesis, characterization and antibacterial activity of silver nanoparticles by actinomycetes isolative. Int J Nano Dimens 4:77–83

    Google Scholar 

  • Otari SV, Patil RM, Nadaf NH, Ghosh SJ, Pawar SH (2012) Green biosynthesis of silver nanoparticles from an actinobacteria Rhodococcus sp. Mater Lett 72:92–94

    Article  CAS  Google Scholar 

  • Oza G, Pandey S, Gupta A, Kesarkar R, Sharon M (2012) Biosynthetic reduction of gold ions to gold nanoparticles by Nocardia farcinica. J Microbiol Biotechnol Res 4:511–515

    Google Scholar 

  • Pal S, Tak YK, Song JM (2007) Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium Escherichia coli. Appl Environ Microbiol 27:1712–1720

    Article  CAS  Google Scholar 

  • Panacek A, Kvitek L, Prucek R, Kolar M, Vecerova R, Pizurova N, Sharma VK, Nevecna T (2006) Silver colloid nanoparticles: synthesis, characterization, and their antibacterial activity. J Phys Chem 110:16248–16253

    Article  CAS  Google Scholar 

  • Pandey S, Oza G, Mewada A, Sharon M (2012) Green synthesis of highly stable gold nanoparticles using Momordica charantia as nano fabricator. Arch App Sci Res 4(2):1135–1141

    CAS  Google Scholar 

  • Pattekari P, Z heng Z, Zhang X, Levchenko T, Torchilinb V, Lvov Y (2011) Top-down and bottom-up approaches in production of aqueous nanocolloids of low solubility drug paclitaxel. Phys Chem Chem Phys 13:9014–9019

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Prabhu S, Poulose EK (2012) Silver nanoparticles: mechanism of anti-microbial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 2:32

    Article  Google Scholar 

  • Prakasham RS, Buddana SK, Yannam SK, Guntuku GS (2012) Characterization of silver nanoparticles synthesized by using marine isolate Streptomyces albidoflavus. J Microbiol Biotechnol 22:614–621

    Article  CAS  PubMed  Google Scholar 

  • Prasad R (2014) Synthesis of silver nanoparticles in photosynthetic plants. J Nanopart: 963961. https://doi.org/10.1155/2014/963961

    Article  CAS  Google Scholar 

  • Prasad R, Swamy VS (2013) Antibacterial activity of silver nanoparticles synthesized by bark extract of Syzygium cumini. Journal of Nanoparticles. https://doi.org/10.1155/2013/431218

    Article  CAS  Google Scholar 

  • Prasad R, Pandey R, Barman I (2016) Engineering tailored nanoparticles with microbes: quo vadis. WIREs Nanomed Nanobiotechnol 8:316–330. https://doi.org/10.1002/wnan.1363

    Article  Google Scholar 

  • Prasad R, Jha A, Prasad K (2018a) Exploring the Realms of Nature for Nanosynthesis. Springer International Publishing (ISBN 978-3-319-99570-0). https://www.springer.com/978-3-319-99570-0

  • Prasad R, Kumar V, Kumar M, Shanquan W (2018b) Fungal Nanobionics: Principles and Applications. Springer Singapore (ISBN 978-981-10-8666-3). https://www.springer.com/gb/book/9789811086656

  • Rajamanickam U, Mylsamy P, Viswanathan S, Muthusamy P (2012) Biosynthesis of zinc nanoparticles using actinomycetes for antibacterial food packaging. In: International Conference on Nutrition and Food Sciences IPCBEE vol 39 IACSIT

    Google Scholar 

  • Rajasree SRR, Suman TY (2012) Extracellular biosynthesis of gold nanoparticles using a gram negative bacterium Pseudomonas fluorescens. Asian Pac J Trop Dis 2:S796–S799

    Article  CAS  Google Scholar 

  • Raut RW, Haroon ASM, Malghe US, Nikam BT, Kashid SB (2013) Rapid biosynthesis of platinum and palladium metal nanoparticles using root extract of Asparagus racemosus Linn. Adv Mater Lett 4(8):650–654

    Article  CAS  Google Scholar 

  • Sadhasivam S, Shanmugam P, Yun K (2010) Biosynthesis of silver nanoparticles by Streptomyces hygroscopicus and antimicrobial activity against medically important pathogenic microorganisms. Colloids Surf B: Biointerfaces 81:358–362

    Article  CAS  PubMed  Google Scholar 

  • Sanjenbam P, Gopal JV, Kannabiran K (2014) Anticandidal activity of silver nanoparticles synthesized using Streptomyces sp. VITPK1. J De Mycologie Médicale. Available from: https://doi.org/10.1016/j.mycmed.2014.03.004

    Article  CAS  PubMed  Google Scholar 

  • Sastry M, Ahmed A, Khan MI, Kumar R (2003) Biosynthesis of metal nanoparticles using fungi and actinomycetes. Curr Nanosci 85(2):162–170

    CAS  Google Scholar 

  • Selvakumar P, Viveka S, Prakash S, Jasminebeaula S, Uloganathan R (2012) Antimicrobial activity of extracellularly synthesized silver nanoparticles from marine derived Streptomyces rochei. Int J Pharm Biol Sci 3:188–197

    CAS  Google Scholar 

  • Shang L, Nienhaus K, Nienhaus GU (2014) Engineered nanoparticles interacting with cells: size matters. J Nano Biotechnol 12:5

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Shah R, Oza G, Pandey S, Sharon M (2012) Biogenic fabrication of gold nanoparticles using Halomonas Salina. J Microbiol Biotechnol Res 2(4):485–492

    CAS  Google Scholar 

  • Sharma VK, Yngard RA, Lin Y (2009) Silver nanoparticles: green synthesis and their antimicrobial activities. Adv Colloid Interf Sci 145:83–96

    Article  CAS  Google Scholar 

  • Shirley AD, Dayanand A, Sreedhar B, Dastager SG (2010) Antimicrobial activity of silver nanoparticles synthesized from novel Streptomyces species. Dig J Nanomater Biostruc 5:447–451

    Google Scholar 

  • Sintubin L, De Windt W, Dick J, Mast J, van der Ha D, Verstraete W, Boon N (2009) Lactic acid bacteria as reducing and capping agent for the fast and efficient production of silver nanoparticles. Appl Microbiol Biotechnol 84:741–761

    Article  CAS  PubMed  Google Scholar 

  • Sivalingham P, Antony JJ, Siva D, Achiraman S, Anbarasu K (2012) Mangrove Streptomyces sp. BDUKAS10 as nanofactory for fabrication of bactericidal silver nanoparticles. Colloids Surf B: Biointerfaces 98:12–17

    Article  CAS  Google Scholar 

  • Subashini J, Kannabiran K (2013) Antimicrobial activity of Streptomyces sp. VITBT7 and its synthesized silver nanoparticles against medically important fungal and bacterial pathogens. Der Pharm Lett 5:192–200

    CAS  Google Scholar 

  • Sukanya MK, Saju KA, Praseetha PK, Sakthivel G (2013) Potential of biologically reduced silver nanoparticles from Actinomycete cultures. J Nanosci:1–8

    Google Scholar 

  • Sundarmoorthi E, Devarasu S, Vengadesh Prabhu K (2011) Antimicrobial and wound healing activity of silver nanoparticles synthesized from Streptomyces aureofaciens. Int J Pharm Res Dev 12:69–75

    Google Scholar 

  • Sunitha A, Rimal IRS, Geo S, Sornalekshmi S, Rose A, Praseetha PK (2013) Evaluation of antimicrobial activity of biosynthesized iron and silver nanoparticles using the fungi Fusarium oxysporum and Actinomycetes sp. on human pathogens. Nano Biomed Eng 5:39–45

    Google Scholar 

  • Sunitha A, Geo S, Sukanya S, Praseetha PK, Dhanya RP (2014) Biosynthesis of silver nanoparticles from actinomycetes for therapeutic applications. Int J Nano Dimens 5:155–162

    Google Scholar 

  • Thakker JN, Dalwadi P, Dhandhukia PC (2013) Biosynthesis of gold nanoparticles using Fusarium oxysporum f.sp. cubense JT1, a plant pathogenic fungus. ISRN Biotechnol, 5 pages. https://doi.org/10.5402/2013/515091

    Google Scholar 

  • Tsibakhashvili NY, Kirkesali EI, Pataraya DT, Gurielidze MA, Kalabegishvili TL, Gvarjaladze DN, Tsertsvadze GI, Frontasyeva MV, Zinicovscaia II, Wakstein MS, Khakhanov SN, Shvindina NV, Shklover VY (2011) Microbial synthesis of silver nanoparticles by Streptomyces glaucus and Spirulina platensis. Adv Sci Lett 4:3408–3417

    Article  CAS  Google Scholar 

  • Usha R, Prabu E, Palaniswamy M, Venil CK, Rajendran R (2010) Synthesis of metal oxide nanoparticles by Streptomyces sp for development of antimicrobial textiles. Glob J Biotechnol Biochem 5:153–160

    CAS  Google Scholar 

  • Vala AK (2014) Exploration on green synthesis of gold nanoparticles by a marine-derived fungus Aspergillus sydowii. Environ Prog Sustain Energy. https://doi.org/10.1002/ep.11949

    Article  CAS  Google Scholar 

  • Vidya C, Hiremath S, Chandraprabha MN, Antonyraj MAL, Gopala IV, Jain A, Bansal K (2013) Green synthesis of ZnO nanoparticles by Calotropis Gigantea. Int J Curr Eng Technol 1:118–120

    Google Scholar 

  • Vidyasagar GM, Shankaravva B, Begum R, Imrose, Raibagkar RL (2012) Antimicrobial activity of silver nanoparticles synthesized by Streptomyces species JF714876. Int J Pharm Sci Nanotechnol 5:1638–1642

    Google Scholar 

  • Waghmare SS, Deshmukh AM, Kulkarni W, Oswaldo LA (2011) Biosynthesis and characterization of manganese and zinc nanoparticles. Univ J Environ Res Technol 1:64–69

    CAS  Google Scholar 

  • Waghmare SS, Deshmukh AM, Sadowski Z (2014) Biosynthesis, optimization, purification and characterization of gold nanoparticles. Afr J Microbiol Res 8:138–146

    Article  CAS  Google Scholar 

  • Zonooz NF, Salouti M (2011) Extracellular biosynthesis of silver nanoparticles using cell filtrate of Streptomyces sp. ERI-3. Scientia Iranica 18(6):1631–1635

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. School of Biotechnology, National Institute of Technology Calicut, Kozhikode, Kerala, India

    T. Aswani, Sasi Reshmi & T. V. Suchithra

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  1. T. Aswani
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  2. Sasi Reshmi
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  3. T. V. Suchithra
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Correspondence to T. V. Suchithra .

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  1. Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India

    Ram Prasad

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Aswani, T., Reshmi, S., Suchithra, T.V. (2019). Actinomycetes: Its Realm in Nanotechnology. In: Prasad, R. (eds) Microbial Nanobionics. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-16383-9_5

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