Skip to main content

Local Recurrence After Surgery

  • Chapter
  • First Online:
Breast Diseases

Abstract

Local recurrence (LR) is the return of ipsilateral breast disease, while locorregional relapse is the resurgence of neoplasia in the breast and/or drainage chains after conservative surgery or mastectomy for the treatment of cancer. The psychological impact may be significant for women, since it means a new surgical approach, new alternatives of systemic treatment, causing a feeling of intractability of the disease and decrease of the possibility of cure. LR rates have been decreasing over time: earlier diagnosis, evolution of imaging and pathological analysis, and the addition of adjuvant treatment (especially systemic) are factors related to better locorregional control.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Recommended Readings

  1. Braunstein LZ, Taghian AG, Niemierko A, et al. Breast-cancer subtype, age, and lymph node status as predictors of local recurrence following breast-conserving therapy. Breast Cancer Res Treat. 2017;161(1):173. The risk of recurrence after conservative surgery is greater in non-luminal subtypes, young patients and number of compromised lymph nodes, which are similar to post-mastectomy risks.

    Article  PubMed  Google Scholar 

  2. Hattangadi-Gluth JA, Wo JY, Nguyen PL, et al. Basal subtype of invasive breast cancer is associated with a higher risk of true recurrence after conventional breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2012;82(3):1185–91. Patients with baseline histological subtype and HER2 presented higher rates of local recurrence after surgical treatment. Chemotherapy and target therapy act concurrently to decrease local recurrence.

    Article  PubMed  Google Scholar 

  3. Huang E, Buchholz TA, Meric F, et al. Classifying local disease recurrences after breast conservation therapy based on location and histology: new primary tumors have more favorable outcomes than true local disease recurrences. Cancer. 2002;95(10):2059. Patients with a new tumor have better survival rates when compared to patients with true recurrence; however, they present a higher chance of contralateral carcinoma. Patients with true recurrence have a greater chance of distant metastasis.

    Article  PubMed  Google Scholar 

  4. Maaskant-Braat AJ, Voogd AC, Roumen RM, et al. Repeat sentinel node biopsy in patients with locally recurrent breast cancer: a systematic review and meta-analysis of the literature. Breast Cancer Res Treat. 2013;138(1):13–20. A meta-analysis with 692 patients showed an identification rate of 84.5% in the present study. Among these, 47% of the lymph nodes were found in extra-axillary homolateral chains, mainly the contralateral axilla and the internal mammary chain.

    Article  PubMed  Google Scholar 

  5. Yi M, Buchholz TA, Meric-Bernstam F, Bedrosian I, et al. Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning. Ann Surg. 2011;253(3):572. Evaluation of 397 patients, differentiating true recurrence and second primary tumor, which present different clinical evolution.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Consortia

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

BBSG – Brazilian Breast Study Group. (2019). Local Recurrence After Surgery. In: Novita, G., Frasson, A., Millen, E., Zerwes, F., Cavalcante, F. (eds) Breast Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-13636-9_54

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-13636-9_54

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-13635-2

  • Online ISBN: 978-3-030-13636-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics