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Non-Hodgkin's Lymphoma in Childhood and Adolescence pp 131–149Cite as

Prognostic Factors in Childhood and Adolescent Non-Hodgkin Lymphoma

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Abstract

Pediatric non-Hodgkin lymphoma (pNHL) is a heterogeneous group of diseases in their morphologic characteristics, clinical behavior, biological features, and response to therapy. Understanding the complexity of pNHL and predicting which subset of patients will not respond to primary treatment or will suffer a relapse are crucial. In this chapter, we will discuss clinical and biological factors that have been found to be of prognostic significance in pNHL. The discussion will be limited to anaplastic large cell lymphoma, T-cell lymphoblastic lymphoma, and aggressive mature B-cell lymphomas, the most common subtypes of NHL affecting children and adolescents.

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Acknowledgments

The authors would like to thank Elisa Carraro and Erin Morris, RN, for their careful assistance in the development of this chapter.

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Authors and Affiliations

  1. Pediatric Hematology and Oncology Unit, Department of Women’s and Children’s Health, University of Padova, Padova, Italy

    Marta Pillon

  2. Division of Hematology/Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA

    Ana C. Xavier

  3. Department of Pediatrics, New York Medical College, Valhalla, NY, USA

    Mitchell S. Cairo

  4. Department of Medicine, New York Medical College, Valhalla, NY, USA

    Mitchell S. Cairo

  5. Department of Pathology, New York Medical College, Valhalla, NY, USA

    Mitchell S. Cairo

  6. Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, USA

    Mitchell S. Cairo

  7. Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA

    Mitchell S. Cairo

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  1. Marta Pillon
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  2. Ana C. Xavier
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  3. Mitchell S. Cairo
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Correspondence to Mitchell S. Cairo .

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Editors and Affiliations

  1. University of Toronto, The Hospital for Sick Children, Toronto, ON, Canada

    Oussama Abla

  2. Medical University of Vienna, St. Anna Children’s Hospital, Vienna, Wein, Austria

    Andishe Attarbaschi

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Pillon, M., Xavier, A.C., Cairo, M.S. (2019). Prognostic Factors in Childhood and Adolescent Non-Hodgkin Lymphoma. In: Abla, O., Attarbaschi, A. (eds) Non-Hodgkin's Lymphoma in Childhood and Adolescence. Springer, Cham. https://doi.org/10.1007/978-3-030-11769-6_11

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