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Biomarkers in Inflammatory Bowel Diseases pp 155–167Cite as

UC Surveillance

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Abstract

Patients with inflammatory bowel disease (IBD) have a significant risk of developing colorectal cancer (CRC). Regular colonoscopic surveillance and dysplasia detection remains the mainstay of CRC risk management. The efficacy of colonoscopic surveillance in preventing CRC remains poor with a considerable number of surveillance patients presenting with interval or advanced CRC. This chapter will focus on clinical and molecular risk factors associated with CRC development. A particular consideration will be given to challenges in detecting and managing dysplasia, with reference to our latest understanding of how CRC evolves from a molecular perspective that could ultimately pave the way for biomarker discovery.

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Authors and Affiliations

  1. St. George Hospital, Sydney, NSW, Australia

    Chang-Ho Ryan Choi

  2. Inflammatory Bowel Disease Unit, St. Marks’ Hospital, Harrow, UK

    Ibrahim Al-Bakir

  3. Cancer and Evolution Laboratory, Barts Cancer Institute, Queen Mary University of London, London, UK

    Ibrahim Al-Bakir

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  1. Chang-Ho Ryan Choi
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Editors and Affiliations

  1. St Vincent’s Hospital, The University of Melbourne, Melbourne, VIC, Australia

    Nik Sheng Ding

  2. Austin Health, The University of Melbourne, Melbourne, VIC, Australia

    Peter De Cruz

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Choi, CH.R., Al-Bakir, I. (2019). UC Surveillance. In: Sheng Ding, N., De Cruz, P. (eds) Biomarkers in Inflammatory Bowel Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-11446-6_13

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