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Pathological Analyses of Colorectal Cancer

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Book cover Emergency Surgical Management of Colorectal Cancer

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

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Abstract

About 15–30% of colorectal cancer present as obstruction or perforation in an emergency setting.

Several studies reported a more advanced stage as well as a more aggressive profile compared to the elective cases.

This review focuses on tumor pathology as a basis for different survival outcomes.

In particular the staging categories T, N, and M as well as the non-anatomic, morphological prognostic factors (tumor grade, lymphovascular invasion) and the TNM ancillary R (residual disease) are discussed.

Careful pathological examination is necessary to confirm the clinical presentation (advanced T category, obstruction, perforation) and to correctly assess nodal staging.

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Author information

Authors and Affiliations

  1. Service of Pathology, Geneva University Hospital and Medical School, Geneva, Switzerland

    Gregoire Arnoux & Giacomo Puppa

  2. Service of Abdominal Surgery and Liver Transplantation, Geneva University Hospital and Medical School, Geneva, Switzerland

    Giulio Cesare Vitali

Authors
  1. Gregoire Arnoux
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  2. Giulio Cesare Vitali
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  3. Giacomo Puppa
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Corresponding author

Correspondence to Giacomo Puppa .

Editor information

Editors and Affiliations

  1. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Nicola de'Angelis

  2. Cambridge Colorectal Unit, Cambridge Biomedical Campus, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke’s Hospital, Cambridge, UK

    Salomone Di Saverio

  3. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Francesco Brunetti

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Arnoux, G., Vitali, G.C., Puppa, G. (2019). Pathological Analyses of Colorectal Cancer. In: de'Angelis, N., Di Saverio, S., Brunetti, F. (eds) Emergency Surgical Management of Colorectal Cancer. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-06225-5_20

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  • DOI: https://doi.org/10.1007/978-3-030-06225-5_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06224-8

  • Online ISBN: 978-3-030-06225-5

  • eBook Packages: MedicineMedicine (R0)

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