Abstract
The central nervous system (CNS) is an uncommon site for fungal infections. A rise of infections in the immunocompromised patient population, along with an increase in their life expectancy due to improved medical care, has led to an increase in the prevalence of CNS mycotic infections. An early diagnosis and prompt management, both medical and surgical, are essential for improving the clinical outcome.
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- BWI:
-
Burn wound infection
- CNS:
-
Central nervous system
- CVID:
-
Common variable immunodeficiency
- HIV:
-
Human immunodeficiency virus
- HSCT:
-
Haematopoietic stem cell transplant
- IV:
-
Intravenous
- MDR:
-
Multidrug-resistant
- SCID:
-
Severe combined immunodeficiency
References
Alexander J, Limaye AP, Ko CW, Bronner MP, Kowdley KV. Association of hepatic iron overload with invasive fungal infection in liver transplant recipients. Liver Transpl. 2006;12:1799–804.
Bozorgi V, Talebitaher M, Shalbaf N, Radmanesh N, Nasri F, Ansari-Ramandi MM. Epidemiological aspects and clinical outcome of patients with Rhinocerebral zygomycosis: a survey in a referral hospital in Iran. Pan Afr Med J. 2016;13(24):232.
Capoor MR, Sarabahi S, Tiwari VK, Narayanan RP. Fungal infections in burns: diagnosis and management. Indian J Plast Surg. 2010;43(Suppl):S37–42.
Chakrabarti A. Epidemiology of central nervous system mycoses. Neurol India. 2007;55:191–7.
Drake KW, Adam RD. Coccidioidal meningitis and brain abscesses: analysis of 71 cases at a referral center. Neurology. 2009;73:1780–6.
Gandhi BV, Bahadur MM, Dodeja H, Aggrwal V, Thamba A, Mali M. Systemic fungal infections in renal diseases. J Postgrad Med. 2005;51(Suppl 1):S30–6.
Leen CL, Brettle RP. Fungal infections in drug users. J Antimicrob Chemother. 1991;28(Suppl A):83–96.
Low C-Y, Rotstein C. Emerging fungal infections in immunocompromised patients. F1000 Med Rep. 2011;3:14.
Murthy JM. Fungal infections of the central nervous system: the clinical syndromes. Neurol India. 2007;55:221–5.
Naik V, Ahmed FU, Gupta A, Garg A, Sarkar C, Sharma B, Mahapatra AK. Intracranial fungal granulomas:a single institutional clinicopathologic study of 66 patients and review of the literature. World Neurosurg. 2015;83:1166–72.
O’Brien D, Stevens NT, Lim CH, O’Brien DF, Smyth E, Fitzpatrick F, Humphreys H. Candida infection of the central nervous system following neurosurgery: a 12-year review. Acta Neurochir (Wien). 2011;153:1347–50.
Osman NM, Gomaa AA, Sayed NM, Abd el Aziz AA. Microarray detection of fungal infection in pulmonary tuberculosis. Egypt J Chest Dis Tuberc. 2013;62:151–7.
Scully EP, Baden LR, Katz JT. Fungal brain infections. Curr Opin Neurol. 2008;21:347–52.
Sethi PK, Khanna L, Batra A, Anand I, Sethi NK, Torgovnick J, Arsura E. Central nervous system fungal infections: observations from a large tertiary hospital in northern India. Clin Neurol Neurosurg. 2012;114:1232–7.
Shankar SK, Mahadevan A, Sundaram C, Sarkar C, Chacko G, Lanjewar DN, Santosh V, Yasha TC, Radhakrishnan VV. Pathobiology of fungal infections of the central nervous system with special reference to the Indian scenario. Neurol India. 2007;55:198–215.
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Gupta, S., Behari, S. (2019). Predisposing Factors. In: Turgut, M., Challa, S., Akhaddar, A. (eds) Fungal Infections of the Central Nervous System. Springer, Cham. https://doi.org/10.1007/978-3-030-06088-6_5
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DOI: https://doi.org/10.1007/978-3-030-06088-6_5
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