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Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders pp 207–233Cite as

Advances in Biomarker Studies in Autism Spectrum Disorders

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Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1118))

Abstract

Autism spectrum disorder (ASD) is a neurological and developmental condition that begins early in childhood and lasts throughout life. The epidemiology of ASD is continuously increasing all over the world with huge social and economical burdens. As the etiology of autism is not completely understood, there is still no medication available for the treatment of this disorder. However, some behavioral interventions are available to improve the core and associated symptoms of autism, particularly when initiated at an early stage. Thus, there is an increasing demand for finding biomarkers for ASD. Although diagnostic biomarkers have not yet been established, research efforts have been carried out in neuroimaging and biological analyses including genomics and gene testing, proteomics, metabolomics, transcriptomics, and studies of the immune system, inflammation, and microRNAs. Here, we will review the current progress in these fields and focus on new methods, developments, research strategies, and studies of blood-based biomarkers.

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Acknowledgments

The authors would like to acknowledge the National Natural Science Foundation of China (grant no. 31870825) and Shenzhen Bureau of Science, Technology and Information (nos. JCYJ20150402100258220, JCYJ20150529164656093, JCYJ20170412110026229) for funds to support this work.

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  1. Liming Shen, and Yuxi Zhao contributed equally to this work.

Authors and Affiliations

  1. College of Life Science and Oceanography, Shenzhen University, Shenzhen, People’s Republic of China

    Liming Shen, Yuxi Zhao, Huajie Zhang, Sijian Xia, Javed Iqbal, Xu Kun Liu & Fang Yao

  2. Maternal and Child Health Hospital of Baoan, Shenzhen, People’s Republic of China

    Chengyun Feng, Yan Gao & Qi Hong

  3. Department of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China

    Danqing Zhao

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  1. Liming Shen
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Correspondence to Liming Shen .

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    Paul C. Guest

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Shen, L. et al. (2019). Advances in Biomarker Studies in Autism Spectrum Disorders. In: Guest, P. (eds) Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders. Advances in Experimental Medicine and Biology(), vol 1118. Springer, Cham. https://doi.org/10.1007/978-3-030-05542-4_11

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