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Exploring the Benefits of Endophytic Fungi via Omics

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Book cover Advances in Endophytic Fungal Research

Part of the book series: Fungal Biology ((FUNGBIO))

Abstract

Endophytic fungi constitute a remarkably diverse, ubiquitous group of eukaryotes with the ability to synthesize secondary metabolites of clinical significance. Their presence has an advantageous effect on growth and health of host plants under duress. They have also been envisaged as a source of diverse medicinal compounds since the discovery of taxol, a prominent anti-cancer drug. In this chapter, we have discussed how resident endophytic fungi aids the host plant in tackling various forms of biotic and abiotic stresses. Their therapeutic potential, viz. cancer cytotoxicity, immunomodulatory, anti-parasitic and anti-pathogenic potential have also been reviewed here. This chapter also explores the plethora of literature available for genomics, metagenomics, transcriptomics, proteomics and metabolomics of endophytic fungi alongside their available web-resources. Applications of omics-based studies on these mutualistic biotrophs have been instrumental in discovery of many unanswered and novel aspects of their biosynthetic potential and overall biology. Data reservoir on fungal endophytes has been constantly growing over the past decades and this reservoir can pave the route of future exploration of these beneficial organisms in therapeutics, biology and evolution via emergent and evolving modes of analysis like machine learning and more.

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Authors and Affiliations

  1. Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Hasnahana Chetia, Debajyoti Kabiraj, Sunita Ojha, Manash Pratim Barkataki & Utpal Bora

  2. Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Biju Bharali, Dharitri Saikia, Tinka Singh, Ponnala Vimal Mosahari & Utpal Bora

  3. Department of Bioengineering and Technology, Gauhati University Institute of Science and Technology (GUIST), Gauhati University, Guwahati, Assam, India

    Pragya Sharma

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Chetia, H. et al. (2019). Exploring the Benefits of Endophytic Fungi via Omics. In: Singh, B. (eds) Advances in Endophytic Fungal Research. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-030-03589-1_4

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