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Neurodevelopmental Outcomes

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Congenital Hyperinsulinism

Part of the book series: Contemporary Endocrinology ((COE))

Abstract

Infants and children with hyperinsulinism are at high risk of brain damage. Multiple studies have demonstrated the increased prevalence of both neurodevelopmental abnormalities (26–48%) and seizures (13–29%) in the hyperinsulinism population. Individuals are at risk of poor neurodevelopmental outcomes regardless of the duration of the hyperinsulinism or treatment modality. All children with hyperinsulinism require screening for developmental issues and swift intervention if abnormalities are identified.

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Authors and Affiliations

  1. Division of Endocrinology and Diabetes, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Katherine Lord & Diva D. De León-Crutchlow

Authors
  1. Katherine Lord
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  2. Diva D. De León-Crutchlow
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Corresponding author

Correspondence to Diva D. De León-Crutchlow .

Editor information

Editors and Affiliations

  1. Division of Endocrinology and Diabetes, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Diva D. De León-Crutchlow

  2. Division of Endocrinology and Diabetes, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Charles A. Stanley

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Lord, K., De León-Crutchlow, D.D. (2019). Neurodevelopmental Outcomes. In: De León-Crutchlow, D., Stanley, C. (eds) Congenital Hyperinsulinism. Contemporary Endocrinology. Humana Press, Cham. https://doi.org/10.1007/978-3-030-02961-6_14

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  • DOI: https://doi.org/10.1007/978-3-030-02961-6_14

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-030-02960-9

  • Online ISBN: 978-3-030-02961-6

  • eBook Packages: MedicineMedicine (R0)

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