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Cutaneous Squamous Cell Carcinoma

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Evidence-Based Procedural Dermatology

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Abstract

Cutaneous squamous cell carcinoma (cSCC) may be treated surgically, with destructive modalities, or through the use of topical agents. The risk of cSCC metastasis has been shown to increase with tumor size and depth, ear location, and immunosuppression. For cSCC lesions with higher-risk features, excision with postoperative margin assessment and Mohs micrographic surgery (MMS) are considered most effective, with MMS best utilized in locations with minimal excess tissue and/or near vital anatomic structures. While cryosurgery and electrodesiccation and curettage may be used for low-risk cSCC, current evidence supports the use of photodynamic therapy and topical agents for low-risk cSCC in situ only.

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Authors and Affiliations

  1. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Nina R. Blank

  2. Department of Dermatology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Kishwer Nehal & Erica Lee

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  1. Nina R. Blank
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  2. Kishwer Nehal
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  1. Department of Dermatology, Northwestern University, Chicago, IL, USA

    Murad Alam

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Blank, N.R., Nehal, K., Lee, E. (2019). Cutaneous Squamous Cell Carcinoma. In: Alam, M. (eds) Evidence-Based Procedural Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-02023-1_43

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