Abstract
According to the theory proposed by Sperry (1), (2) patterning of synaptic connections is handled by growth mechanism directly, independently of function and with very high “selectivity”.According to the “selectivity theory” the establishment and maintenance of synaptic connections depends on highly specific cytochemical affinities (“similarities”?). This mechanism can be regulated in at least three different ways: a) differentiation (genetically directed) b) induction by means of contact c) other effects, like “embryonal gradient”.
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Giacobini, E. (1971). Biochemistry of the Developing Autonomic Neuron. In: Paoletti, R., Davison, A.N. (eds) Chemistry and Brain Development. Advances in Experimental Medicine and Biology, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7236-3_12
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DOI: https://doi.org/10.1007/978-1-4684-7236-3_12
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