Abstract
One of the most striking differences between coronaviruses and other enveloped RNA viruses is that they bud into intracellular membranes. Only bunyaviruses behave similarly (1). Coronavirions have been observed in the lumens of endoplasmic reticulum (ER) and Golgi apparatus from cells infected with various coronaviruses such as mouse hepatitis virus (MHV) (2–5), avian infectious bronchitis virus (IBV) (6) and porcine enteric Coronavirus (7) The assembled virions then appear in smooth-walled vesicles en route to the plasma membrane (PM) where they are probably released from the cell by exocytosis (4,8).
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Keywords
- Infectious Bronchitis Virus
- Endoplasmic Reticulum Membrane
- Microsomal Membrane
- Protease Digestion
- Mouse Hepatitis Virus
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© 1984 Plenum Press, New York
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Rottier, P., Brandenburg, D., Armstrong, J., van der Zeijst, B., Warren, G. (1984). In Vitro Assembly of the Murine Coronavirus Membrane Protein E1. In: Rottier, P.J.M., van der Zeijst, B.A.M., Spaan, W.J.M., Horzinek, M.C. (eds) Molecular Biology and Pathogenesis of Coronaviruses. Advances in Experimental Medicine and Biology, vol 173. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9373-7_5
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