Abstract
Porcine transmissible gastroenteritis virus (TGEV) has been shown to agglutinate erythrocytes using a2,3-linked sialic acid on the cell surface as binding site. The hemagglutinating activity requires the pretreament of virus with neuraminidase. We obtained evidence that TGEV recognizes not only N-acetylneuraminic acid but also N-glycoloylneuraminic acid, a sialic acid present on many porcine cells.
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Keywords
- Sialic Acid
- Infectious Bronchitis Virus
- Hemagglutinating Activity
- Hemagglutination Assay
- Neuraminic Acid
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References
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Schultze B., Gross H.-J., Brossmer R., Klenk, H.-D. and Herrler G. Hemagglutinating encephalomyelitis virus attaches to N-acetyl-9-O-acetylneuraminic acid-containing receptors on erythrocytes: comparison with bovine coronavirus and influenza C virus. Virus Res. 1990; 16: 185–194.
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© 1995 Springer Science+Business Media New York
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Schultze, B., Enjuanes, L., Herrler, G. (1995). Analysis of the Sialic Acid-Binding Activity of Transmissible Gastroenteritis Virus. In: Talbot, P.J., Levy, G.A. (eds) Corona- and Related Viruses. Advances in Experimental Medicine and Biology, vol 380. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1899-0_59
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DOI: https://doi.org/10.1007/978-1-4615-1899-0_59
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