Abstract
In order to study the mechanical behavior of the vertebrate eye cornea under intraocular pressure, digital volume correlation (DVC) has been carried out on a series of volume images generated through swept source optical coherence tomography (SSOCT). Phantom and porcine cornea samples under posterior inflation conditions were considered. The effect of noise and reconstruction uncertainties were evaluated through correlation of two repeated reconstructed volumes without loading. The strain resolutions of the DVC were obtained after calculating their mean and standard deviation values. Then, several reconstructed volumes were recorded one after the other, introducing a rigid body translation of 10 μm between successive volume images and the mean and standard deviation of strain were also identified. The volume deformation process of both phantom and porcine cornea samples under inflation test from 2 to 2.25 kPa were then visualized and the distribution patterns of displacement and strain fields analyzed with a view to stiffness identification.
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References
Pepose JS, Feigenbaum SK, Qazi MA, Sanderson JP, Roberts CJ (2007) Changes in corneal biomechanics and intraocular pressure following LASIK using static, dynamic, and noncontact tonometry. Am J Ophthalmol 143:39–47
Kaluzy BJ, Kaluzny JJ, Szkulmowska A, Gorczynska I, Szkulmowski M, Bajraszewski T et al (2006) Spectral optical coherence tomography a novel technique for cornea imaging. Cornea 25:960–965
Fujimoto JG (2003) Optical coherence tomography for ultrahigh resolution in vivo imaging. Nat Biotechnol 23:1361–1367
Boyce BL, Grazier JM, Jones RE, Nguyen TD (2008) Full-field deformation of bovine cornea under constrained inflation conditions. Biomaterials 29:3896–3904
Elsheikh A, Alhasso D, Rama P (2008) Assessment of the epithelium’s contribution to corneal biomechanics. Exp Eye Res 86:445–451
Pierron F, Grédiac M (2012) The virtual fields method. Springer, New-York, p 536. ISBN 978-1-4614-1823-8
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© 2013 The Society for Experimental Mechanics, Inc.
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Fu, J., Haghighi-Abayneh, M., Pierron, F., Ruiz, P.D. (2013). Assessment of Corneal Deformation Using Optical Coherence Tomography and Digital Volume Correlation. In: Prorok, B., et al. Mechanics of Biological Systems and Materials, Volume 5. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4427-5_22
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DOI: https://doi.org/10.1007/978-1-4614-4427-5_22
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