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Structure, Function, and Genetics of Ribosomes pp 68–86Cite as

Structure of Ribosomes and Their Components by Advanced Techniques of Electron Microscopy and Computer Image Analysis

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Part of the book series: Springer Series in Molecular Biology ((SSMOL))

Abstract

High-resolution electron microscopy plays a leading role in the structural analysis of biological macromolecules and is the most direct method for obtaining detailed information on the morphology, topography of the components, and functional sites of ribosomes. Electron microscopy (EM) has been important also for the interpretation of data obtained by a variety of physico-chemical techniques (for references see Chambliss et al., 1980; Liljas, 1982; Wittmann, 1983) on ribosomal protein locations, relative protein-protein distances, and protein-RNA binding sites, data which are more valuable when mapped within a well-defined structural framework provided, at present, by EM.

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Authors
  1. M. Boublik
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  2. G. T. Oostergetel
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  3. J. S. Wall
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  4. J. F. Hainfeld
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  5. M. Radermacher
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  6. T. Wagenknecht
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  7. A. Verschoor
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  8. J. Frank
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Editor information

Editors and Affiliations

  1. Clayton Foundation Biochemical Institute Department of Chemistry, The University of Texas at Austin, 78712, Austin, Texas, USA

    Boyd Hardesty  & Gisela Kramer  & 

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© 1986 Springer-Verlag New York Inc.

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Boublik, M. et al. (1986). Structure of Ribosomes and Their Components by Advanced Techniques of Electron Microscopy and Computer Image Analysis. In: Hardesty, B., Kramer, G. (eds) Structure, Function, and Genetics of Ribosomes. Springer Series in Molecular Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4884-2_4

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  • DOI: https://doi.org/10.1007/978-1-4612-4884-2_4

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-9346-0

  • Online ISBN: 978-1-4612-4884-2

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