The first group of oncogenes to have been discovered form parts of the genomes of acutely transforming retroviruses, which cause hematological or soft tissue cancers in their avian or mammalian hosts. They act in a dominant manner and confer altered growth properties and morphology on specific target cells in mesenchymal tissues or the hematopoetic system.
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© 2007 Springer
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(2007). Oncogenes. In: Molecular Biology of Human Cancers. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-3186-1_4
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DOI: https://doi.org/10.1007/978-1-4020-3186-1_4
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