Abstract
There are various possible explanations for adipose tissue hypertrophy in lymphedema. There is a physiological imbalance of blood flow and lymphatic drainage, resulting in the impaired clearance of lipids and their uptake by macrophages.1,2 There is increasing support, however, for the view that the fat cell is an endocrine organ and a cytokine-activated cell,3,4 and chronic inflammation plays a role here.5,6
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Brorson, H. (2011). Surgical Treatment of Postmastectomy Lymphedema – Liposuction. In: Lee, BB., Bergan, J., Rockson, S. (eds) Lymphedema. Springer, London. https://doi.org/10.1007/978-0-85729-567-5_50
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DOI: https://doi.org/10.1007/978-0-85729-567-5_50
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