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Changes in the Brain pp 189–209Cite as

Cancer Survivorship

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Abstract

Brain tumors can be primary, arising from neuroepithelial cells or secondary to metastatic disease, and can arise anywhere from the cerebral hemispheres above the tentorium to the posterior fossa. These tumors may cause destruction or displacement of normal brain tissue resulting in neurological compromise. Oncologic management of brain tumors includes surgical resection, radiation therapy and chemotherapy. Survival factors such as age, extent of systemic disease, neurological status at time of diagnosis, and number and sites of metastases are considered when determining optimal treatment. When combined with oncologic management, rehabilitation can serve to relieve symptoms, improve quality of life, enhance functional independence, and prevent further complications in patients with brain tumors.

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References

  • Armstrong, C. L., Corn, B. W., Ruffer, J. E., Pruitt, A. A., Mollman, J. E., & Phillips, P. C. (2000). Radiotherapeutic effects on brain function: Double dissociation of memory systems. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 13(2), 101–111.

    CAS  PubMed  Google Scholar 

  • Armstrong, T. S., & Gilbert, M. R. (2007). Net clinical benefit: Functional endpoints in brain tumor clinical trials. Current Oncology Reports, 9(1), 60–65.

    Article  PubMed  Google Scholar 

  • Braddom, R. L. (Ed.). (2007). Physical medicine and rehabilitation (3rd ed.). Philadelphia: Saunders Elsevier.

    Google Scholar 

  • Christie, L. A., Acharya, M. M., Parihar, V. K., Nguyen, A., Martirosian, V., & Limoli, C. L. (2012). Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy. Clinical Cancer Research, 18(7), 1954–1965. doi:10.1158/1078-0432.CCR-11-2000.

    Article  CAS  PubMed  Google Scholar 

  • Correa, D. D., DeAngelis, L. M., Shi, W., Thaler, H., Glass, A., & Abrey, L. E. (2004). Cognitive functions in survivors of primary central nervous system lymphoma. Neurology, 62(4), 548–555.

    Article  CAS  PubMed  Google Scholar 

  • Correa, D. D., Shi, W., Abrey, L. E., Deangelis, L. M., Omuro, A. M., Deutsch, M. B., et al. (2012). Cognitive functions in primary CNS lymphoma after single or combined modality regimens. Neuro-Oncology, 14(1), 101–108. doi:10.1093/neuonc/nor186.

    Article  CAS  PubMed  Google Scholar 

  • Cotran, R. S., Kumar, V., & Collins, T. (Eds.). (1999). Robbins pathologic basis of disease (6th ed.). Philadelphia: W.B. Saunders Company.

    Google Scholar 

  • Davis, M. P., Zimmermann, C., Feyer, P., & Ortner, P. (Eds.). (2011). Supportive oncology. Philadelphia: Elsevier.

    Google Scholar 

  • DeAngelis, L. M., Delattre, J. Y., & Posner, J. B. (1989). Radiation-induced dementia in patients cured of brain metastases. Neurology, 39(6), 789–796.

    Article  CAS  PubMed  Google Scholar 

  • DeLisa, J. A. (2001). A history of cancer rehabilitation. Cancer, 92(4 Suppl), 970–974.

    Article  CAS  PubMed  Google Scholar 

  • Dietz, J. H. (Ed.). (1981). Rehabilitation oncology. New York: John Wiley and Sons Inc.

    Google Scholar 

  • Gilbert, M., Armstrong, T., & Meyers, C. (2000). Issues in assessing and interpreting quality of life in patients with malignant glioma. Seminar in Oncology, 27(3 Suppl 6), 20–26.

    CAS  Google Scholar 

  • Giordana, M. T., & Clara, E. (2006). Functional rehabilitation and brain tumour patients. A review of outcome. Neurological Science, 27(4), 240–244. doi:10.1007/s10072-006-0677-9.

    Article  CAS  Google Scholar 

  • Heilman, K. M., Watson, R. T., & Valenstein, E. (1993). Neglect and related disorders. Clinical Neuropsychology, 3, 279–336.

    Google Scholar 

  • Huang, M. E., Cifu, D. X., & Keyser-Marcus, L. (1998). Functional outcome after brain tumor and acute stroke: A comparative analysis. Archives of Physical Medicine and Rehabilitation, 79(11), 1386–1390.

    Article  CAS  PubMed  Google Scholar 

  • Janda, M., Steginga, S., Dunn, J., Langbecker, D., Walker, D., & Eakin, E. (2008). Unmet supportive care needs and interest in services among patients with a brain tumour and their carers. Patient Education and Counseling, 71(2), 251–258.

    Article  PubMed  Google Scholar 

  • Kirshblum, S., O’Dell, M. W., Ho, C., & Barr, K. (2001). Rehabilitation of persons with central nervous system tumors. Cancer, 92(4 Suppl), 1029–1038.

    Article  CAS  PubMed  Google Scholar 

  • Koretz, B. K., & Moore, A. A. (2001). Assessment of the geriatric patient: A practical approach. Journal of Clinical Outcomes Management, 8(7), 35–40.

    Google Scholar 

  • Lee, E. Q., Arrillaga-Romany, I. C., & Wen, P. Y. (2012). Neurologic complications of cancer drug therapies. Continuum (Minneap Minn), 18(2), 355–365. doi:10.1212/01.CON.0000413663.42798.64.

    Google Scholar 

  • Lu-Emerson, C., & Eichler, A. F. (2012). Brain metastases. Continuum (Minneap Minn), 18(2), 295–311. doi:10.1212/01.CON.0000413659.12304.a6.

    Google Scholar 

  • Meyers, C. A., Weitzner, M. A., Valentine, A. D., & Levin, V. A. (1998). Methylphenidate therapy improves cognition, mood, and function of brain tumor patients. Journal of Clinical Oncology, 16(7), 2522–2527.

    CAS  PubMed  Google Scholar 

  • Mukand, J. A., Blackinton, D. D., Crincoli, M. G., Lee, J. J., & Santos, B. B. (2001). Incidence of neurologic deficits and rehabilitation of patients with brain tumors. American Journal of Physical Medicine and Rehabilitation, 80(5), 346–350.

    Article  CAS  PubMed  Google Scholar 

  • Newton, H. B. (2012). Neurological complications of chemotherapy to the central nervous system. Handbook of Clinical Neurology, 105, 903–916. doi:10.1016/B978-0-444-53502-3.00031-8.

    Article  PubMed  Google Scholar 

  • O’Neill, B. P., Buckner, J. C., Coffey, R. J., Dinapoli, R. P., & Shaw, E. G. (1994). Brain metastatic lesions. Mayo Clinic Proceedings, 69(11), 1062–1068.

    Article  PubMed  Google Scholar 

  • Ownsworth, T., Hawkes, A., Steginga, S., Walker, D., & Shum, D. (2008). A biopsychosocial perspective on adjustment and quality of life following brain tumor: A systematic evaluation of the literature. Disability and Rehabilitation, 29, 1–18.

    Google Scholar 

  • Patchell, R. A. (1996). The treatment of brain metastases. Cancer Investigation, 14(2), 169–177.

    Article  CAS  PubMed  Google Scholar 

  • Raffa, R. B. (2011). A proposed mechanism for chemotherapy-related cognitive impairment (“chemo-fog”). Journal of Clinical Pharmacy and Therapeutics, 36(3), 257–259. doi:10.1111/j.1365-2710.2010.01188.x.

    Article  CAS  PubMed  Google Scholar 

  • Rogers, L. R. (2012). Neurologic complications of radiation. Continuum (Minneap Minn), 18(2), 343–354. doi:10.1212/01.CON.0000413662.35174.a8.

    Google Scholar 

  • Stubblefield, M. D., & O’Dell, M. W. (Eds.). (2009). Cancer rehabilitation. New York: Demos Medical.

    Google Scholar 

  • Syrjala, K. L., Stover, A. C., Yi, J. C., Artherholt, S. B., & Abrams, J. R. (2010). Measuring social activities and social function in long-term cancer survivors who received hematopoietic stem cell transplantation. Psychooncology, 19(5), 462–471.

    Article  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Memorial Sloan Kettering Cancer Center, 515 Madison Avenue, 5th Floor, New York, NY, 10022, USA

    Lisa M. Ruppert M.D.

  2. Memorial Sloan Kettering Cancer Center, 515 Madison Avenue, 4th Floor, New York, NY, 10022, USA

    Gabrielle Miskovitz OTR/L

  3. Kessler Institute for Rehabilitation, 1199 Pleasant Valley Way, West Orange, NJ, 07052, USA

    Michael D. Stubblefield M.D.

Authors
  1. Lisa M. Ruppert M.D.
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  2. Gabrielle Miskovitz OTR/L
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  3. Michael D. Stubblefield M.D.
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Corresponding author

Correspondence to Lisa M. Ruppert M.D. .

Editor information

Editors and Affiliations

  1. Kessler Foundation, East Hanover, New Jersey, USA

    Nancy D. Chiaravalloti

  2. Department of Occupational Therapy, Steinhardt School of Culture, Education, and Human Development, New York University, New York, New York, USA

    Yael Goverover

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Ruppert, L.M., Miskovitz, G., Stubblefield, M.D. (2017). Cancer Survivorship. In: Chiaravalloti, N., Goverover, Y. (eds) Changes in the Brain. Springer, New York, NY. https://doi.org/10.1007/978-0-387-98188-8_9

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  • DOI: https://doi.org/10.1007/978-0-387-98188-8_9

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-98187-1

  • Online ISBN: 978-0-387-98188-8

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