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Mechanisms of Nitric Oxide Reactions Mediated by Biologically Relevant Metal Centers

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Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine II

Part of the book series: Structure and Bonding ((STRUCTURE,volume 154))

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Notes

  1. 1.

    The flash photolysis kinetics studies generally employ a pump-probe approach. Typically, the pump pulse is delivered from a laser. The time frame of the experiment will depend in part upon the length of the laser pulse, which in some systems can be as short as a few fs. The probe can be a continuous or pulsed source at wavelengths ranging from the ultraviolet into the infrared depending upon the detection system, the time constant of which is typically matched to that of the pump system.

  2. 2.

    The quantum yield Φ is a quantitative measure of the photoreaction efficiency and can be defined as the number of moles of the photoproduct formed (either transiently or permanently) per Einstein of light absorbed by the system.

Abbreviations

AN:

Acetonitrile

aq:

Aqueous

Cbl:

Cobalamin

cGMP:

Cyclic guanylyl monophosphate

CysSH:

Cysteine

CytII :

Ferrous cytochrome c

DAC:

Bis(9-Anthracylmethyl)cyclam

DFT:

Density functional theory

dmp:

2,9-Dimethyl-1,10-phenanthroline

DNIC:

Dinitrosyl iron complexes

dpp:

2,9-Diphenyl-1,10-phenanthroline

EDTA4– :

Ethylenediamintetraacetate

EPR:

Electron paramagnetic resonance

F8Por:

Tetrakis(2,6-difluorophenyl)-porphyrinato

GSH:

Glutathione

GSNO:

S-Nitrosoglutathione

GTP:

Guanylyl triphosphate

Hb:

Hemoglobin

Mb:

Myoglobin

metMb:

Metmyoglobin

MLCT:

Metal-to-ligand charge transfer

MNIC:

Mononitrosyl iron complexes

NiR:

Nitrite reductase

NOS:

Nitric oxide synthase

Por:

Porphyrinato

PPIX:

Protoporphyrin IX

RBS:

Roussin’s black salt

RRE:

Roussin’s red esters

RRS:

Roussin’s red salt

sGC:

Soluble guanylyl cyclase

THF:

Tetrahydrofuran

TMPS:

Tetra(sulfonato-mesityl)porphyrinato

TPP:

Tetraphenylporphyrinato

TPPS:

Tetra(4-sulfonatophenyl)porphyrin

tren:

Bis-(2-aminoethyl)amine

UV:

Ultraviolet

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Acknowledgements

Reactivity studies of nitrogen oxides in the UCSB laboratory of PCF have long been supported by the Division of Chemistry of the US National Science Foundation (Current grant CHE-1058794). JCMP thanks Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) for fellowship support.

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Correspondence to Peter C. Ford .

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Ford, P.C., Pereira, J.C.M., Miranda, K.M. (2013). Mechanisms of Nitric Oxide Reactions Mediated by Biologically Relevant Metal Centers. In: Mingos, D. (eds) Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine II. Structure and Bonding, vol 154. Springer, Berlin, Heidelberg. https://doi.org/10.1007/430_2013_117

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