Oxidative Stress in Applied Basic Research and Clinical Practice


The current definition of oxidative stress (OS) is an abnormal level of reactive oxygen-nitrogen species leading to cellular injury, which can be prevented by antioxidant (AOX) intake providing a therapeutic advantage. When this delicate balance is perturbed, homeostasis is compromised and disease may develop. Extensive research has shown a strong correlation with these events. Springer has been a leader in publishing books related to oxidative stress since 1998. The goal of the Oxidative Stress in Basic Research and Clinical Practice series is to present data showing relationships between OS and biomarkers, as well as results from clinical trials illustrating the efficacy of AOX supplementation. Each volume covers a medical specialty, or major disease known to be associated with an imbalance between free radical production and AOX defense. The expectation of the series is to critically evaluate the potential of AOXs in therapeutic intervention using simple and sophisticated methodology that could be adapted to point-of-care testing for diagnosis, intervention strategies and prognosis. This approach of combining methodology, technology and epidemiology will benefit medical practitioners and may subsequently improve health care and reduce medical cost. Editors anticipate updating their respective volumes as frequently as warranted by emerging new studies.